Back
 OJCD  Vol.10 No.1 , March 2020
Bacteriological Profile of Pneumopathies in Chronic Renal Failure at the University Hospital Center of Point-G in Mali
Abstract: Introduction: Chronic renal failure (CKD) is defined as a glomerular filtration rate (GFR) of less than 60 ml/min/1.73m2 for more than 3 months [1]. Infectious complications are a major source of morbidity in patients with chronic renal failure. In Mali, we have no data on pneumopathies in this population, hence the interest of this study. The objective of this work was to determine the frequency of pneumopathies in patients with chronic renal failure, describe the clinical radio-types, identify the microorganisms involved, and assess the renal prognosis of pneumopathies. Materials and Methods: This was an 18-month prospective and descriptive study from January 1, 2018 to June 30, 2019 conducted in the nephrology and hemodialysis department of the University Hospital of Point G. Included were patients hospitalized during our study period with CKD associated with pneumopathy on a chest X-ray. Not included were all patients hospitalized outside the study period, all CKD cases without pneumonia, patients with incomplete records, and non-consenting patients. Results: We examined 1111 patients, 35 of whom presented an image on chest X-ray related to pneumopathy, a frequency of 3.15% of cases. Twenty-one men (60%) and 14 women (40%) with a sex ratio of 1.5. The mean age was 46.8 ± 13.9 years with extremes of 23 and 76 years. The types of pneumopathy on the chest X-ray were: alveolar pneumopathy: 23 cases (65.7%), pleuropneumopathy: 10 cases (28.6%) and cavitary pneumopathy: 2 cases (5.7%). Cytobacteriological sputum examination was positive in 65.7%; leukocytes (68.6% of cases). The germs found were: Klebsiella pneumoniae (25.7% of cases), Escherica coli (11.4%), Pseudomonas aeruginosa (5.7%), Staphylococcus aureus (5.7%), Citrobacter freundi (5.7%), Enterococus sp. (2.9%), Enterobacter cloacae (2.9%), Candida albicans (5.7%). The search for acid-alcohol-resistant bacilli (BAAR) in sputum was positive in 4 cases (11.4%). There was an association between the results of cytobacteriological examination of sputum and the results of BAAR testing of sputum (p = 0.046).
Cite this paper: Sy, S. , Samaké, M. , Yattara, H. , Coulibaly, M. , Diallo, B. , Fofana, A. , Diallo, D. , Kodio, A. , Sidibé, M. , Coulibaly, N. , Touré, A. , Sy, D. , Tangara, M. and Fongoro, S. (2020) Bacteriological Profile of Pneumopathies in Chronic Renal Failure at the University Hospital Center of Point-G in Mali. Open Journal of Clinical Diagnostics, 10, 18-28. doi: 10.4236/ojcd.2020.101002.
References

[1]   Hulot, J.-S. (2017) Chronic Renal Failure and Chronic Renal Diseases in University College of Teachers of Nephrology. 7th Edition, Edition Ellipses, Paris.

[2]   Rieu, Ph. and Touré, F. (2006) Infections and Immunosuppression during Uremia. Jean-Hamburger Nephrology News. Necker Hospital, 229-250.

[3]   Hoen, B., Kessler, M., Hestin, D., et al. (1995) Risk Factors for Bacterial Infections in Chronic Haemodialysis Adult Patients: A Multicentre Prospective Survey. Nephrology Dialysis Transplantation, 10, 377-381.

[4]   Kessler, M., Hoen, B., Mayeux, D., et al. (1993) Bacteremia in Patients on Chronic Hemodialysis. A Multicenter Prospective Survey. Nephron, 64, 95-100.
https://doi.org/10.1159/000187285

[5]   Allon, M., Depner, T.A., Radeva, M., et al. (2003) Impact of Dialysis Dose and Membrane on Infection Related Hospitalization and Death: Result of the HEMO Study. Journal of the American Society of Nephrology, 14, 1863-1870.
https://doi.org/10.1097/01.ASN.0000074237.78764.D1

[6]   Cohen, G., Haagweber, M. and Horl, W.H. (1997) Immune Dysfunction in Uremia. Kidney International, 52, S79-S82.

[7]   Maiga, S., Adambounou, A.-S. and Aziagbe, A.-K. (2017) Particularities of Bacterial Pneumopathies of the Elderly Subject in Hospital in Lomé (Togo). 10 p.

[8]   Maroua, B., et al. (2017) Explorations of Bacterial Infections in the Nephrology Department of Tlemcen University Hospital. 68 p.

[9]   Ouldittou, I., Serhane, H., Aitbatahar, S., Sajiai, H. and Amro, L. (2017) Service de pneumologie, Pcim laboratory, Ucam, Marrakech, Morocco. Bacteriological Profile of Pneumonia in Diabetic Subjects. 67 p.

[10]   Fekih Hassen, M., et al. (2014) Severe Community Lung Diseases in Intensive Care: Clinical, Bacteriological Characteristics and Prognostic Factors: A Tunisian Experience. Revue de Pneumologie Clinique, 71 p.

[11]   Ikram, D. (2012) Infections in Chronic Haemodialysis Patients (About 81 Cases). Thesis, Fez.

[12]   Dammin, G.J., Couch, N.P. and Murray, J.E. (1957) Prolonged Survival of Skin Homografts in Uremic Patients. Annals of the New York Academy of Sciences, 64, 967-976.
https://doi.org/10.1111/j.1749-6632.1957.tb52488.x

[13]   Fathia, Z., et al. (2017) Description and Place of Bacteriological Techniques in the Management of Pulmonary Infections Tunisia. 121 p.

[14]   Chemlal, A., Karimi, I., Benabdellah, N., Alaoui, F., Alaoui, S., Haddiya, I., et al. (2015) Urinary Infections in the Patient with Chronic Renal Failure in Nephrology: Bacteriological Profile and Prognosis. Nephrology & Therapeutic, 11, 399.
https://doi.org/10.1016/j.nephro.2015.07.401

[15]   Diallo, S., Sissoko, B.F., Toloba, Y., Hassane, F., Mbaye, O., Tamara, A., Keita, B. and Fongoro, S. (2007) Tuberculosis in Chronic Hemodialysis. Respiratory Disease Review, 24, 108.
https://doi.org/10.1016/S0761-8425(07)72721-3

[16]   El Amrani, M., Asserraji, M., Bahadi, A., El Kabbaj, D. and Benyahia, M. (2016) Tuberculosis on Hemodialysis. Tropical Medicine and Health, 26, 262-266.
https://doi.org/10.1684/mst.2016.0569

 
 
Top