d in all patients (n = 40) and demonstrated lithiasis associated with primary biliary dilatation. Laboratory tests highlighted a cholestasis syndrome in 8 patients 20%. Hyperleukocytosis was found in 5% of patients (n = 2). The risk factors found are reported in Table 2.
Table 1. Clinical signs found.
Table 2. Risk factors.
Table 3. Seat of the lithiasis and associated lesion.
The surgical procedure: The site of choledochal lithiasis and associated lesions are reported in Table 3.
The surgical procedure consisting of a cholecystectomy associated with a longitudinal cholodocotomy with extraction of the computation and establishment of a kheroside drain in the common bile duct in 39 patients (97.5%) and a transcystic drain in a patient (2.5%). Verification of the permeability of the bile was performed. Cholangiography was performed 3 days postoperative in all patients and not objectified residual calculation, but it revealed a case of bile leakage 2.5% (n = 1). No patients received intraoperative cholangiography because of a lack of technical facilities in our structure. The Kher drain was removed postoperatively in 39 patients, or 99% of cases. The morbidity was marked by a case of biliary fistula is 2.5% (n = 1) and a case of abscess of the wall is 2.5% of cases. The mortality was 5% (=2), and the follow-up was simple in 90% of cases.
In Mali the actual frequency of cholelithiasis is not known. The frequency observed in the western series varies between 10% - 15% of the population among which 5% - 15% suffer from a lithiasis of the main gallstone (CBD)  . Surgery of the CBD represented in our study 2.8% of all surgery for gallstones, this frequency has been reported in men by studies carried out in Niger and Burkina   . The prevalence and incidence of cholelithiasis increase with age. The average age of 60 years of our series does not differ from those of the Ivorian and French series  . Cholelithiasis is deemed to 2 to 3 times common in women than in men both in Africa and in the West  . This higher frequency in women is explained by the role of female sex hormones, contraception and estrogen therapie  . The sex ratio was 0.4 in our series against 3 in the study of Keita  . The febrile painful jaundice is observed in 50% of cases and achieves the choledochal syndrome which combines in less than 24 hours to 48 hours in the order: pain of the right hypochondrium, fever and jaundice. This triad known as the Charcot triad is one of the key elements in the clinical diagnosis of choledochal lithiasis. It was observed in 33% of cases in the series reported by Tham  against 100% in our series, this difference is explained by the fact that in our series the patients consulted late or all the clinical signs were already present. Ultrasound hepatobiliary was the morphological examination performed in all the patients of our series is 100% of cases. In the series of Tham  its percentage of realization was also 100% and made it possible to highlight in 60% of cases the lithiasis against 100% in our series. The performance of ultrasound in the diagnosis of CBD lithiasis remains difficult to assess. Sensitivity figures reported in the literature range from 15 to 75%. The examination conditions and the type of calculation are determining elements. Some authors   have consistently asked the abdominal computed tomography (CT) in 71% - 76% of cases in our study CT was requested when the result of an ultrasound was not contributory. In most series, biological tests have shown a cholestasis syndrome that varies between 20% and 30%   . In our study, cholestasis syndrome was observed in 8 patients (20%) and leukocytosis observed in 2 cases (20%). Laparoscopy and sphincterotomy oscopique are the standard treatment of stones in the CBD in the West, these surgical approaches have many advantages over conventional surgery, they are not feasible in Mali for lack of technical facilities. This is why all the patients of our series were operated by laparotomy is 100% of cases, the median incision was the most used in our series, in the series reported by Keita  the right subcostal incision was the most performed, 80.7% of cases. The choice of the type of incision depends on the preference of the surgeon. Some authors believe that the right subcostal incision gives easy access to the bile ducts. The surgical procedure performed in our study was associated with cholecystectomy longitudinal cholodochotomie with stone extraction. External biliary drainage was performed in all patients either by a Kher drain 39 cases (97.5%) or a trans cystic drain 1 case (2.5%) against respectively 66% and 34% in the study conducted by N. Houes  . Cholangiography intraoperative was not performed in our patients by lack of technical support. However, if the technical conditions allow it, intraoperative cholangiography must be systematic to verify the patency of the bile duct and the existence of residual stones. It was performed in all patients in the study reported by N. Houes  or 100% of cases. An under-hepatic drain was placed in all of our patients 50 cases (100%) against 23% of cases reported by Traoré S. S.  . This drainage is intended to collect a possible bile leak or bleeding. A cholangiogram was performed in all our patients 3 days after the operation through the Kher drain or cystic drain. It did not objectify residual calculation but 1 case (2.5%) of biliary leak was found it did not require recovery. The Kher drain was removed at 8 days post operative. The overall morbidity was 10% in our series against 25% observed in the Keita series  . The morbidity observed in our series was marked by 1 case (2.5%) of biliary fistula and 1 case (2.5%) of wall abscess. The suites were simple in 90% of the cases.
The cholelithiasis is a potentially serious pathology, laparoscopy and interventional endoscopy replaced laparotomy in the West, however, laparotomy remains the first way in Mali. Morbidity can be reduced by the use of the endoscopic and laparoscopic approach.
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