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 IJCM  Vol.10 No.2 , February 2019
Value of Thromboelastography in Judging Abnormal Coagulation Function in Patients with Early Hemorrhagic Shock
Abstract: Objective: To detect the changes of coagulation function in patients with early hemorrhagic shock by thromboelastography (TEG). Methods: TEG was performed in 50 patients with early hemorrhagic shock and surgical indications. The TEG parameters were compared with 50 healthy people. The coagulation and fibrinolysis in patients with early hemorrhagic shock were observed. Results: In terms of coagulation parameters, the R value decreased, the α angle increased, and the K value and MA value did not change significantly in patients with early hemorrhagic shock. Fibrinolytic aspects: EPL, LY30 observations have no significant changes compared to normal values. Conclusion: The plasma coagulation factor activity is increased in patients with early hemorrhagic shock; the fibrin level is increased; the blood is in a hypercoagulable state; and the fibrinolysis function is not changed. The timely detection of TEG can be used for coagulation function monitoring and blood transfusion therapy in patients with surgical hemorrhagic shock. It provides an important basis for preventing the formation of deep vein thrombosis.
Cite this paper: Yan, Y. and Li, J. (2019) Value of Thromboelastography in Judging Abnormal Coagulation Function in Patients with Early Hemorrhagic Shock. International Journal of Clinical Medicine, 10, 70-77. doi: 10.4236/ijcm.2019.102007.
References

[1]   MacLeod, J.B., Winkler, A.M., Mccoy, C.C., et al. (2014) Expertly Induced Coagulopathy (ETIC): Prevalence across the Injury Spectrum. Injury, 45, 910-915.
https://doi.org/10.1016/j.injury.2013.11.004

[2]   Hoffman, M. (2015) Coagulation in Liver Disease. Seminars in Thrombosis and Hemostasis, 41, 447-454.
https://doi.org/10.1055/s-0035-1550435

[3]   Wei, K.K., Liao, Z.N. and Zhang, H.M. (2018) Advances in the Application of Thromboelastography in Cerebrovascular Diseases. Journal of Clinical Neurology, 31, 71-72.

[4]   Fan, R.J., Liu, B., Li, D.J. and Pu, W.H. (2016) The Application Value of Thrombus Elasticity Diagram in Guiding Perioperative Clinical Blood Transfusion. Journal of Ningxia Medical University, 38, 1255.

[5]   Lyu, X., Qiao, W., Li, D., et al. (2017) Impact of Perioperative Blood Transfusion on Clinical Outcomes in Patients with Colorectal Liver Metastasis after Hepatectomy: A Meta-Analysis. Oncotarget, 8, 41740-41748.
https://doi.org/10.18632/oncotarget.16771

[6]   Lawson, P.J. and Moore, H.B. (2018) Microfluidics Contrasted to Thrombelastography: Perplexities in Defining Hypercoagulability. Journal of Surgical Research, 231, 54-61.

[7]   Bai, J., Zheng, Q.W., Fu, S.H., et al. (2013) Association between Thromboelastography System and Thromb Oembolic and Bleeding Events in Chinese Aged People. International Journal of Clinical and Experimental Medicine, 6, 310-319.

[8]   Cotton, B.A., Minei, K.M., Radwan, Z.A., Matijevic, N., et al. (2012) Admission Rapid Throm-Belastography Predicts Development of Pulmonary Embolism in Trauma Patients. Journal of Trauma and Acute Care Surgery, 72, 1470-1477.
https://doi.org/10.1097/TA.0b013e31824d56ad

[9]   Autar, R. (1996) Nursing Assessment of Clients at Risk of Deep Vein Thrombosis (DVT): The Autar DVT Scale. Journal of Advanced Nursing, 23, 763-770.
https://doi.org/10.1111/j.1365-2648.1996.tb00049.x

[10]   Toukh, M., Siemens, D.R., Black, A., et al. (2014) Thromboelastography Identifies Hypercoagulablilty and Predicts Thromboembolic Complications in Patients with Prostate Cancer. Thrombosis Research, 133, 88-95.
https://doi.org/10.1016/j.thromres.2013.10.007

[11]   Wang, J.J. and Zhou, J.Z. (2018) Study on the Effects of Different Fluid Resuscitation Strategies on Complications and Prognosis in Patients with Hemorrhagic Shock. Chinese General Practice, 16, 1446-1448.

[12]   Song, J.G., Jeong, S.M., Jun, I.G., et al. (2014) Five-Minute Parameter of Thromboelastometry Is Sufficient to Detect Thrombocytopenia and Hypofibrinogenaemia in Patients Undergoing Liver Transplantation. British Journal of Anaesthesia, 112, 290-297.
https://doi.org/10.1093/bja/aet325

[13]   Huang, R.H., et al. (2012) Application of Thromboelastography in the Monitoring of Coagulation Function in Splenectomy and Resection. Journal of Practical Medicine, 28, 3211-3212.

[14]   Song, P. (2017) The Application Value of Thromboelastography and Conventional Coagulation Test in Plasma Infusion in Patients with Severe Infections. Clinical Medicine, 32, 56-57.

[15]   Xu, J.L. (2018) The Application of Thromboelastography in Clinical Rational Use of Blood in Hospitalized Patients with Severe. Chinese and Foreign Medical, 31, 51-53.

[16]   Zhang, X.C., Zheng, X., Li, C.Y., et al. (2017) Diagnostic Value of Thromboelastogram for Predicting Perioperative Thrombosis in Hip and Knee Joint Replacement. Chinese Journal of Bone and Joint Surgery, 10, 386-389.

[17]   Testroote, M.J. and Wittens, C.H. (2013) Prevention of Venous Thromboembolism in Patients Undergoing Surgical Treatment of Varicose Veins. Phlebology, 28, 86-90.
https://doi.org/10.1177/0268355512475121

 
 
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