OJGen  Vol.1 No.3 , December 2011
Prenatal testing and termination of future pregnancies in Arab mothers of children with severe defects: impact of Moslem cleric or physician on the decision making
ABSTRACT
The authors investigated: 1) How many of 250 Israeli Arab mothers (50% in consanguineous marriages) of babies with severe congenital anomalies had undergone prenatal testing during pregnancy, and how many had refused termination of pregnancy (TOP) when recommended; 2) Why TOP had been refused; 3) Attitudes regarding prenatal testing and TOP in future pregnancies; and 4) Whether the women would have changed their decision had they been able to talk to a Moslem cleric or Moslem doctor in addition to the regular personnel. Eighty seven (35%) refused to even consider TOP, 55 (22%) agreed to undergo TOP, and 87 (35%) agreed provided the procedure would be performed before 120 days gestation. The remainder were undecided. Of 195 women, the addition of a Moslem religious cleric or physician to the Committee would influence 89 (46%) and 55 (28%), respectively, to change their opinion and agree to TOP, and 26 (13%) and 10 (5%), respectively, to change their opinion and agree to TOP prior to 120 days of gestation. The remainder either continued to refuse TOP or were undecided.

Cite this paper
nullJaber, L. , Halpern, G. and Samara, S. (2011) Prenatal testing and termination of future pregnancies in Arab mothers of children with severe defects: impact of Moslem cleric or physician on the decision making. Open Journal of Genetics, 1, 54-59. doi: 10.4236/ojgen.2011.13010.
References
[1]   Shepard, T.H. (1986) Human teratogenicity. Advances in Pediatrics, 33, 225-268.

[2]   Naderi, S. (1979) Congenital abnormalities in newborns of consanguineous and nonconsanguineous parents. Obstetrics and Gynecology, 53, 195-199.

[3]   Magnus, P., Berg, K. and Bjerkedal, T. (1985) Association of parental consanguinity with decreased birth weight and increased rate of early death and congenital malformations. Clinical Genetics, 28, 335-342. doi:10.1111/j.1399-0004.1985.tb00407.x

[4]   Shami, S.A., Schmitt, L.H. and Bittles, A.H. (1989) Consanguinity related prenatal and postnatal mortality of the populations of seven Pakistani Punjab cities. Journal of Medical Genetics, 26, 267-271. doi:10.1136/jmg.26.4.267

[5]   Bittles, A.H., Mason, W.M., Greene, J., et al. (1991) Reproductive behavior and health in consanguineous marriages. Science, 252, 789-794. doi:10.1126/science.2028254

[6]   Zlotogora, J. (1997) Autosomal recessive diseases among Palestinian Arabs. Journal of Medical Genetics, 34, 765- 766. doi:10.1136/jmg.34.9.765

[7]   Jaber, L., Halpern, G.J. and Shohat, M. (1998) The impact of consanguinity worldwide. Community Genetics, 1, 12-17. doi:10.1159/000016130

[8]   Jaber, L., Merlob, P., Bu, X., et al. (1992) Marked parental consanguinity as a cause for increased major malformations in an Israeli Arab community. American Journal of Medical Genetics, 44, 1-6. doi:10.1002/ajmg.1320440102

[9]   Jaber, L., Bailey-Wilson, J.E., Haj-Yehia, M., et al. (1994) Consanguineous matings in an Israeli-Arab community. Archives of Pediatrics and Adolescent Medicine, 148, 412-415.

[10]   Jaber, L., Halpern, G.J. and Shohat, T. (2000) Trends in the frequencies of consanguineous marriages in the Israeli Arab community. Clinical Genetics, 58, 106-110. doi:10.1034/j.1399-0004.2000.580203.x

[11]   Dixon, W.J. (1993) BMDP Statistical Software. University of California Press, Berkeley.

[12]   Hessini, L. (2007) Abortion and Islam: Policies and practice in the Middle East and North Africa. Reproductive Health Matters, 15, 75-84. doi:10.1016/S0968-8080(06)29279-6

[13]   Shaikh, S. (2003) Family planning, contraception and abortion in Islam: Undertaking Khilafah: Moral agency, justice and compassion. In: Maguire, D. Ed., Sacred Choices: The Case for Contraception and Abortion in World Religions, Oxford University Press, Oxford, 1-4.

[14]   Alkuraya, F.S. and Kilani, R.A. (2001) Attitude of Saudi families affected with hemoglobinopathies towards prenatal screening and abortion and the influence of religious ruling (Fatwa). Prenatal Diagnosis, 21, 448-451. doi:10.1002/pd.76

[15]   Jaber, L., Dolfin, T., Shohat, T., et al. (2000) Prenatal diagnosis for detecting congenital malformations: Acceptance among Israeli Arab women. Israel Medical Association Journal, 2, 346-350.

[16]   Zahed, L. and Bou-Dames, J. (1997) Acceptance of first- trimester prenatal diagnosis for the haemoglobinopathies in Lebanon. Prenatal Diagnosis, 17, 423-428. doi:10.1002/(SICI)1097-0223(199705)17:5<423::AID-PD68>3.0.CO;2-P

[17]   Zahed, L., Nabulsi, M., Bou-Ghanim, M., et al. (1999) Acceptance of prenatal diagnosis for genetic disorders in Lebanon. Prenatal Diagnosis, 19, 1109-1112. doi:10.1002/(SICI)1097-0223(199912)19:12<1109::AID-PD708>3.0.CO;2-V

[18]   Tsianakas, V. and Liamputtong, P. (2002) Prenatal testing: the perceptions and experiences of Muslim women in Australia. Journal of Reproductive and Infant Psychology, 20, 7-24. doi:10.1080/02646830220106767

[19]   Ahmed, S., Green, J.M. and Hewison, J. (2006) Attitudes towards prenatal diagnosis and termination of pregnancy for thalassaemia in pregnant Pakistani women in the North of England. Prenatal Diagnosis, 26, 248-257. doi:10.1002/pd.1391

[20]   Ahmed, S., Atkin, K., Hewison, J., et al. (2006) The influence of faith and religion and the role of religious and community leaders in prenatal decisions for sickle cell disorders and thalassaemia major. Prenatal Diagnosis, 26, 801-809. doi:10.1002/pd.1507

[21]   Zlotogora, J., Barges, S., Bisharat, B., et al. (2006) Genetic disorders among Palestinian Arabs. 4: Genetic clinics in the community. American Journal of Medical Genetics, 140, 1644-1646. doi:10.1002/ajmg.a.31342

[22]   Basel-Vanagaite, L., Taub, E., Halpern, G.J., et al. (2007) Genetic screening for autosomal recessive nonsyndromic mental retardation in an isolated population in Israel. European Journal of Human Genetics, 15, 250-253. doi:10.1038/sj.ejhg.5201750

 
 
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