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 Health  Vol.10 No.8 , August 2018
Penile Cancer in Liberia: A Case Report and Review of the Literature
Abstract: Background: Penile cancer is uncommon in Liberia with no record of its occurrence so far in the literature. Its occurrence worldwide is significantly affected by cultural or religious practices like childhood circumcision. Smoking, poor penile hygiene and inflammatory processes in the presence of smegma increase the risk of its occurrence. Objective: To review the first case of penile cancer treated in Liberia. Materials and Method: Case report. Case Presentation/Report: Our index patient is a 65-year old man referred from a peripheral centre in acute urinary retention. He also presented with a year history of progressively expanding ulcerative penile lesion affecting the glans and penile shaft. Local examination of the genitalia revealed an ulcerated lesion extending from the glans up to the mid shaft of the penis. The penobulbar urethra was free of induration. The external urethral meatus was infiltrated by the lesion. The scrotum and testes were normal and digital rectal examination revealed a moderately enlarged benign prostate. Bilateral inguinal lymph node enlargement was elicited. A diagnosis of advanced penile cancer with benign prostatic hyperplasia was made. The patient had partial penectomy, reconstruction of new external urethral meatus and inguinal lymphadenectomy. The specimen was histologically confirmed to be Squamous cell Carcinoma of the penis; the resection margins and lymph nodes biopsied were found to be adequate and tumor free respectively. Patient’s post operative recovery was uneventful and he was discharged after a week. His follow up status after 6 months has remained satisfactory. Conclusion: Though rare, penile cancer does occur in Liberia and specialist staff with capacity for diagnosing and surgical intervention remains critical to patients’ outcome. Early intervention improves the chances of better outcome; counseling is critical to prevent treated patient lapsing into depression.
Cite this paper: Ikpi, E. , Konneh, S. , Yunusa, B. , Camara, A. , Clark, A. , Subah, S. , Alele, D. and Sroden, M. (2018) Penile Cancer in Liberia: A Case Report and Review of the Literature. Health, 10, 1132-1139. doi: 10.4236/health.2018.108086.
References

[1]   Christodoulidou, M., Sahdev, V., Houssein, S. and Muneer, A. (2015) Epidemiology of Penile Cancer. Current Problems in Cancer, 39, 126-136.
https://doi.org/10.1016/j.currproblcancer.2015.03.010

[2]   Barnholtzsloan, J.S., Maldonado, J.L., Pow-Sang, J., Giuliano, A.R. and Guiliano, A.R. (2007) Incidence Trends in Primary Malignant Penile Cancer. Urologic Oncology, 25, 361-367.
https://doi.org/10.1016/j.urolonc.2006.08.029

[3]   Spiess, P.E., Horenblas, S., Pagliaro, L.C., Biagioli, M.C., Crook, J., Clark, P.E., et al. (2013) Current Concepts in Penile Cancer. Journal of the National Comprehensive Cancer Network, 11, 617-624.
https://doi.org/10.6004/jnccn.2013.0076

[4]   Wilson, C.N. and Sathiyasusuman, A. (2015) Associated Risk Factors of STIs and Multiple Sexual Relationships among Youths in Malawi. PLoS ONE, 10, 134286.

[5]   Favorito, L.A., Nardi, A.C., Ronalsa, M., Zequi, S.C., Sampaio, F.J. and Glina, S. (2008) Epidemiologic Study on Penile Cancer in Brazil. International Brazilian Journal of Urology, 34, 587-591.
https://doi.org/10.1590/S1677-55382008000500007

[6]   Morrison, B.F. (2014) Risk Factors and Prevalence of Penile Cancer. West Indian Medical Journal, 63, 559-560.

[7]   Parkin, D.M., Ferlay, J., Hamdi-Cherif, M., Sitas, F., Thomas, J.O., Wabinga, H., et al. (2003) Cancer Incidence in Africa. International Agency for Research on Cancer, Lyon.

[8]   Parkin, D.M. (2002) Cancer Incidence in Five Continents. International Agency for Research on Cancer, Lyon.

[9]   Ajekigbe, A.T., Anunobi, C.C., Tijani, K.H., Banjo, A.A. and Nweke, I.G. (2011) Carcinoma of the Penis: Experience from the Lagos University Teaching Hospital Lagos, Nigeria. Nigerian Quarterly Journal of Hospital Medicine, 21, 25-28.

[10]   Abubakar, A., Sule, A. and Haruna, M.S. (2017) Pattern of Penile Cancerin Kano, Nigeria. Journal of Basic and Clinical Sciences,14, 15-17.

[11]   Guimaraes, G.C., Rocha, R.M., Zequi, S.C., Cunha, I.W. and Soares, F.A. (2011) Penile Cancer: Epidemiology and Treatment. Current Oncology Reports, 13, 231-239.
https://doi.org/10.1007/s11912-011-0163-2

[12]   Shabbir, M., Barod, R., Hegarty, P.K. and Minhas, S. (2013) Primary Prevention and Vaccination for Penile Cancer. Therapeutic Advances in Urology, 5, 161-169.
https://doi.org/10.1177/1756287212465456

[13]   Gerber, G. (1994) Carcinoma in Situ of the Penis. Journal of Urology, 151, 829-833.
https://doi.org/10.1016/S0022-5347(17)35099-1

[14]   Wiener, J.S. and Walther, P.J. (1995) The Association of Oncogenic Human Papillomaviruses with Urologicmalignancy. Surgical Oncology Clinics of North America, 4, 257-276.
https://doi.org/10.1016/S1055-3207(18)30452-6

[15]   Harish, K. and Ravi, R. (1995) The Role of Tobacco in Penile Carcinoma. British Journal of Urology, 75, 375-377.
https://doi.org/10.1111/j.1464-410X.1995.tb07352.x

[16]   Hect, S.S., Akerkar, S. and Carmnella, S.G. (1993) Metabolites of Tobacco Specific Nitrosamine 4(methylnitrosamino)-1-(3-pyridyl)-1-Butanone in Smokers Urine. Proceedings of the American Association for Cancer Research, 34, 909.

[17]   Pow-Sang, M.R., Benavente, V., Pow-Sang, J.E., Morante, C., Meza, L., Baker, M., et al. (2002) Cancer of the Penis. Cancer Control, 9, 305-314.
https://doi.org/10.1177/107327480200900405

[18]   Burgers, J.K., Badalament, R.A. and Drago, J.R. (1992) Penile Cancer. Clinical Presentation, Diagnosis, and Staging. Urologic Clinics of North America, 19, 247-256.

[19]   Derakhshani, P., Neubauer, S., Braun, M., Bargmann, H., Heidenreich, A. and Engelmann, U. (1999) Results of 10 Year Follow-Up in Patients with Squamous Cell Carcinoma of the Penis. Urologia Internationalis, 62, 238-244.
https://doi.org/10.1159/000030405

[20]   Cubilla, A.L., Reuter, V., Velazquez, E., Piris, A., Saito, S. and Young, R.H. (2001) Histologic Classification of Penile Carcinoma and Its Relation to Outcome in 61 Patients with Primary Resection. International Journal of Surgical Pathology, 9, 111-120.
https://doi.org/10.1177/106689690100900204

 
 
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