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 AS  Vol.9 No.5 , May 2018
MtsR, an Iron-Dependent Regulator in Streptococcus iniae
Abstract: Streptococcus iniae (S. iniae) is a major pathogen that is capable of resulting severe economic loss to cultured fish. Steadily iron availability from micro-environment is an important virulence factor for pathogens, and S. iniae encodes the iron-transporter MtsABC to accomplish heme utilization, but very little was known about the mechanisms involved in regulating and maintaining iron balance in S. iniae. In this study, the role of a putative iron-dependent transcriptional regulator MtsR was investigated, and the results showed that MtsR regulated the expression of iron-transport mtsABC to control iron homeostasis in S. iniae.
Cite this paper: Wang, J. , Wang, P. , Qin, Y. and Zou, L. (2018) MtsR, an Iron-Dependent Regulator in Streptococcus iniae. Agricultural Sciences, 9, 609-618. doi: 10.4236/as.2018.95042.
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