JCT  Vol.2 No.4 , October 2011
Determination of Metastatic Axillary Lymph Node in Breast Cancer: Differentiation with Dynamic MRI Examination by Signal Intensity-Time Curves
ABSTRACT
Purpose: We aimed to evaluate the role of dynamic magnetic resonance imaging (MRI) in the detection of axillary lymph node metastasis based on the signal intensity-time curves. Materials and Methods: The data of 120 patients (benign patients, n = 91; malignant patients, n = 29) who underwent dynamic breast MRI were reviewed. The lymph nodes with the strongest criteria for malignancy (morphological-dynamic properties) were included in the analysis. Signal intensity-time curves were plotted by the software. Results: Of 29 patients with breast cancer, axillary lymph nodes were involved in 21 and not involved in the remaining 8. There was no significant difference between benign and malignant cases in terms of the distributions of Type Ia, Type Ib and Type IV curves (p = 0.12), whereas a significant difference was found between benign and malignant cases in terms of the distributions of Type II and III curves (p < 0.01). Benign lymph nodes dominantly displayed Type III curves (66.2%), whereas malignant ones dominantly displayed Type II curves (57.2%). Conclusion: On dynamic MRI studies, benign and metastatic lymph nodes display different signal intensity-time curves.

Cite this paper
nullD. Yildirim, B. Ekci, B. Gurses and A. Kaur, "Determination of Metastatic Axillary Lymph Node in Breast Cancer: Differentiation with Dynamic MRI Examination by Signal Intensity-Time Curves," Journal of Cancer Therapy, Vol. 2 No. 4, 2011, pp. 557-566. doi: 10.4236/jct.2011.24076.
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