JBiSE  Vol.4 No.9 , September 2011
Mathematical model for steady state current at ppo-modified micro-cylinder biosensors
ABSTRACT
A Mathemataical model for a modified micro- cylinder electrode in which polyphenol oxidase ( PPO) occurs for all values of the concentration of catechol and o-quinone is analysed. This model is based on system of reaction-diffusion Equations containing a non-linear term related to Michaelis Menten kinetics of the enzymatic reaction. Here a new analytical technique Homotopy Perturbation Method is used to solve the system of non-linear differential Equations that describe the diffusion coupled with a Michaelis-Menten kinetics law. Here we report an analytical expressions pretaining to the concentration of catechol and o-quinone and corresponding current in terms of dimensionless reaction-diffusion parameters in closed form. An excellent agreement with available limiting case is noticed.

Cite this paper
nullVenugopal, K. , Eswari, A. and Rajendran, L. (2011) Mathematical model for steady state current at ppo-modified micro-cylinder biosensors. Journal of Biomedical Science and Engineering, 4, 631-641. doi: 10.4236/jbise.2011.49079.
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