IJOC  Vol.1 No.3 , September 2011
Two Flavones from Acanthospermum hispidum DC and Their Antibacterial Activity
ABSTRACT
Two new flavones, namely 5,7,2’,5’-tetrahydroxy-3,4’-dimethoxyflavone and 5’-acetoxy-5,7,2’-trihydroxy-3, 4’-dimethoxyflavone were successfuly isolated from the leaves of Acanthospermum hispidum DC and identified by UV-Vis, IR, 1H-NMR and EI-MS techniques. Both compounds exhibited antibacterial activity against Salmonella typii, Staphylococcus aureus, Klebsiella pneumoniae, Proteus mirabilis, Bacillus subtilis, Pseudomonas aeruginosa and Shigella dysenteriae with minimum inhibition concentration (MIC) ranging from 0.001 - 0.20 but was inactive against Escherichia coli, Corybacterium pyogenes and Proteus vulgaris.

Cite this paper
nullT. Edewor and A. Olajire, "Two Flavones from Acanthospermum hispidum DC and Their Antibacterial Activity," International Journal of Organic Chemistry, Vol. 1 No. 3, 2011, pp. 132-141. doi: 10.4236/ijoc.2011.13020.
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