IJOC  Vol.1 No.3 , September 2011
Phase Transfer Catalysis of Henry and Darzens Reactions
ABSTRACT
We describe in this work the influence of the addition of phase transfer catalyst in heterogeneous medium liquid/liquid on the output of the reactions of Darzens and Henry. It proves that the reaction of Darzens is favoured in the presence of low base such as K2CO3 and Et3N. Phase transfer catalysis is an efficient activation method in Darzens and Henry reactions. Thus, the Ethylene Diammonium Diacetate (EDD) has a comparable catalytic activity has that of quaternary ammonium salts in the reaction of Darzens.

Cite this paper
nullL. Mhamdi, H. Bohli, Y. Moussaoui and R. Salem, "Phase Transfer Catalysis of Henry and Darzens Reactions," International Journal of Organic Chemistry, Vol. 1 No. 3, 2011, pp. 119-124. doi: 10.4236/ijoc.2011.13018.
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