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 OJMP  Vol.6 No.1 , January 2017
Illness Perception in Gestational Trophoblastic Disease Patients: How Mental Representations Affect Anxiety, Depression, and Infertility-Related Stress
Abstract: Gestational Trophoblastic Disease encompasses a group of pregnancy-related disorders that derive from the placenta. Taking Leventhal’s Common Sense Model as a starting point, this study aims to investigate how illness perception could influence patients’ psychological adaptation to these rare diseases. Thirty-seven women completed: the Illness Perception Questionnaire-Revised, the Beck Depression Inventory Short Form, the State-Trait Anxiety Inventory, and the Fertility Problem Inventory. Results show that the perception of severe illness consequences significantly predicts the level of anxiety patients reported at the time of questionnaire completion. Furthermore, mental representations of illness present a significant association with infertility-related stress. Specifically, the belief in the efficacy of the treatment results in fewer feelings of discomfort and isolation from family and social context due to infertility-related problems. Since patients’ illness perception was found to have a specific impact on both anxiety and infertility-related stress, this variable should be considered in the planning of a clinical intervention.
Cite this paper: Carnelli, L. , Di Mattei, V. , Mazzetti, M. , Bernardi, M. , Di Pierro, R. , Bergamini, A. , Pella, F. , Mangili, G. , Sarno, L. and Candiani, M. (2017) Illness Perception in Gestational Trophoblastic Disease Patients: How Mental Representations Affect Anxiety, Depression, and Infertility-Related Stress. Open Journal of Medical Psychology, 6, 1-15. doi: 10.4236/ojmp.2017.61001.
References

[1]   Mangili, G., Lorusso, D., Brown, J., Pfisterer, J., et al. (2014) Trophoblastic Disease Guidelines of Diagnosis and Management. A Joint Report from the International Society for the Study of Trophoblastic Disease, European Organisation for the Treatment of Trophoblastic Disease, and the Gynecologic Cancer InterGroup. International Journal of Gynecolgical Cancer, 9, 109-116.
https://doi.org/10.1097/IGC.0000000000000294

[2]   Parazzini, F., Ricci, E., Cipriani, S., Bulfoni, G., Mangili, G. and Chiaffarino, F. (2012) Temporal Trends in the Frequency of Hydatidiform Mole in Lombardy, Northern Italy, 1996-2008. International Journal of Gynecological Cancer, 22, 318-322.
https://doi.org/10.1097/IGC.0b013e31823b3504

[3]   Goldstein, D.P. and Berkowitz, R.S. (2012) Current Management of Gestational Trophoblastic Neoplasia. Hematology Oncology Clinics of North America, 26, 111-131.
https://doi.org/10.1016/j.hoc.2011.10.007

[4]   Lurain, J.R. (2010) Gestational Trophoblastic Disease I: Epidemiology, Pathology, Clinical Presentation and Diagnosis of Gestational Trophoblastic Disease, and Management of Hydatidiform Mole. American Journal of Obstetrics and Gynecology, 203, 531-539.
https://doi.org/10.1016/j.ajog.2010.06.073

[5]   Wenzel, L.B., Berkowitz, R.S., Robinson, S., Goldstein, D.P. and Bernstein, M.R. (1994) Psychological, Social and Sexual Effects of Gestational Trophoblastic Disease on Patients and Their Partners. Journal of Reproductive Medicine, 39, 163-167.

[6]   Horowitz, N.S. and Wenzel, L.B. (2009) Psychosocial Consequences of Gestational Trophoblastic Disease. In: Hancock, B.W., Seckl, M.J., Berkowitz, R.S. and Cole, L.A., Eds., Gestational Trophoblastic Disease, 3rd Edition, Wiley, Sheffield, 460-469.

[7]   Di Mattei, V.E., Carnelli, L., Ambrosi, A., Mangili, G., Candiani, M. and Sarno, L. (2014) Gestational Trophoblastic Disease: Psychological Aspects and Fertility Issues. The Journal of Reproductive Medicine, 59, 488-495.

[8]   Di Mattei, V.E., Carnelli, L., Bernardi, M., Pagani Bagliacca, E., Zucchi, P., Lavezzari, L. and Sarno, L. (2015) An Investigative Study into Psychological and Fertility Sequelae of Gestational Trophoblastic Disease: The Impact on Patients’ Perceived Fertility, Anxiety and Depression. PloS ONE, 10, e0128354.
https://doi.org/10.1371/journal.pone.0128354

[9]   Wenzel, L., Berkowitz, R.S., Habbal, R., Newlands, E., Hancock, B., Goldstein, D.P., Seckl, M., Bernstein, M., Strickland, S. and Higgins, J. (2004) Predictors of Quality of Life among Long-Term Survivors of Gestational Trophoblastic Disease. The Journal of Reproductive Medicine, 49, 589-594.

[10]   Hagger, M.S. and Orbell, S. (2003) A Meta-Analytic Review of the Common-Sense Model of Illness Representations. Psychology & Health, 18, 141-184.
https://doi.org/10.1080/088704403100081321

[11]   Jørgensen, I.L., Frederiksen, K., Boesen, E., Elsass, P. and Johansen, C. (2009) An Exploratory Study of Associations between Illness Perceptions and Adjustment and Changes after Psychosocial Rehabilitation in Survivors of Breast Cancer. Acta Oncologica, 48, 1119-1127.
https://doi.org/10.3109/02841860903033922

[12]   Leventhal, H., Meyer, D. and Nerenz, D.R. (1980) The Common Sense Representation of Illness Danger. In: Rachman, S., Ed., Contributions to Medical Psychology, Pergamon Press, New York, 17-30.

[13]   Leventhal, H., Nerenz, D.R. and Steele, D.J. (1984) Illness Representations and Coping with Health Threats. In: Baum, A., Taylor, S.E. and Singer, J.E. Eds., Handbook of Psychology and Health, Volume IV: Social Psychological Aspects of Health, Erlbaum, Hillsdale, NJ, 219-252.

[14]   Llewellyn, C.D., McGurk, M. and Weinman, J. (2007) Illness and Treatment Beliefs in Head and Neck Cancer: Is Leventhal’s Common Sense Model a Useful Framework for Determining Changes in Outcomes over Time? Journal of Psychosomatic Research, 63, 17-26.
https://doi.org/10.1016/j.jpsychores.2007.01.013

[15]   Hopman, P. and Rijken, M. (2014) Illness Perceptions of Cancer Patients: Relationships with Illness Characteristics and Coping. Psycho-Oncology, 24, 11-18.
https://doi.org/10.1002/pon.3591

[16]   Di Mattei, V.E., Carnelli, L., Mazzetti, M., Bernardi, M., Di Pierro, R., Bergamini, A., Mangili, G., Candiani, M. and Sarno, L. (2016) Mental Representation of Illness in Patients with Gestational Trophoblastic Disease: How Do Patients Perceive Their Condition? PLoS ONE, 11, e0153869.
https://doi.org/10.1371/journal.pone.0153869

[17]   Giardini, A., Majani, G., Pierobon, A., Gremigni, P. and Catapano, I. (2007) Contribution to the Italian Validation of the IPQ-R. Giornaleitaliano di Medicina del Lavoroed Ergonomia, 29, A64-A74.

[18]   Moss-Morris, R., Weinman, J., Petrie, K.J., Horne, R., Cameron, L.D. and Buick, D. (2002) The Revised Illness Perception Questionnaire (IPQ-R). Psychology & Health, 17, 1-16.
https://doi.org/10.1080/08870440290001494

[19]   Beck, A.T., Ward, C.H., Mendelson, M., Mock, J. and Erbaugh, J. (1961) An Inventory for Measuring Depression. Archives of General Psychiatry, 4, 561-571.
https://doi.org/10.1001/archpsyc.1961.01710120031004

[20]   Beck, A.T. and Steer, R.A. (1993) Beck Depression Inventory Manual. Psychological Corporation, San Antonio.

[21]   Scilligo, P.F. (1988) La scala di depressione di Beck. In: Scilligo, P. F., Ed., Scale psicologiche 1. Stili, Coppia, Depressione, Amore, Narcisismo, IFREP, Roma.

[22]   Furlanetto, L.M., Mendlowicz, M.V. and Bueno, J.R. (2005) The Validity of the Beck Depression Inventory-Short Form as a Screening and Diagnostic Instrument for Moderate and Severe Depression in Medical Inpatients. Journal of Affective Disorders, 86, 87-91.
https://doi.org/10.1016/j.jad.2004.12.011

[23]   Del Corno, F. and Lang, M. (2009) La diagnositestologica: Test neuropsicologici, test d’intelligenza, test di personalità, testing compterizzato. Francoangeli, Milano.

[24]   Pedrabissi, L. and Santinello, M. (1989) STAI State-Trait Anxiety Inventory Forma Y Manuale. Organizzazioni Speciali, Firenze.

[25]   Spielberger, C.D., Gorsuch, R.C. and Lushene, R.E. (1970) Manual for the State-Trait Anxiety Inventory. Consulting Psychologists Press, Palo Alto.

[26]   Den Oudsten, B.L., Van Heck, G.L., Van der Steeg, A.F., Roukema, J.A. and De Vries, J. (2009) Predictors of Depressive Symptoms 12 Months after Surgical Treatment of Early-Stage Breast Cancer. Psycho-Oncology, 18, 1230-1237.
https://doi.org/10.1002/pon.1518

[27]   McQuellon, R., Wells, M., Hoffman, S., Craven, B., Russell, G., Cruz, J., et al. (1998) Reducing Distress in Cancer Patients with an Orientation Program. Psycho-Oncology, 7, 207-217.
https://doi.org/10.1002/(SICI)1099-1611(199805/06)7:3<207::AID-PON304>3.0.CO;2-T

[28]   Ambrosino, A. and Zurlo, M.C. (2011) La valutazione di dimensioni dello stress, risorse adattive e disagio emozionale in coppie infertili. Doctoral Dissertation, Università degli Studi di Napoli Federico II, Napoli, Italy.
http://www.fedoa.unina.it/id/eprint/9022

[29]   Newton, C.R., Sherrard, M.A. and Glavac, I. (1999) The Fertility Problem Inventory: Measuring Perceived Infertility-Related Stress. Fertility and Sterility, 72, 54-62.
https://doi.org/10.1016/S0015-0282(99)00164-8

[30]   Peterson, B.D., Newton, C.R. and Feingold, T. (2007) Anxiety and Sexual Stress in Men and Women Undergoing Infertility Treatment. Fertility and Sterility, 88, 911-914.
https://doi.org/10.1016/j.fertnstert.2006.12.023

[31]   IBM Corp (2013) IBM SPSS Statistics for Windows (Version 22.0). IBM Corp, Armonk.

[32]   Wenzel, L.B., Berkowitz, R.S., Robinson, S., Bernstein, M.R. and Goldstein, D.P. (1992) The Psychological, Social and Sexual Consequences of Gestational Trophoblastic Disease. Gynecologic Oncology, 46, 74-81.
https://doi.org/10.1016/0090-8258(92)90200-3

[33]   Ferreira, E.G., Maestá, I., Michelin, O.C., de Paula, R.C., Consonni, M. and Rudge, M.V. (2009) Assessment of Quality of Life and Psychologic Aspects in Patients with Gestational Trophoblastic Disease. The Journal of Reproductive Medicine, 54, 239-244.

[34]   Walsh, J.C., Lynch, M., Murphy, A.W. and Daly, K. (2004) Factors Influencing the Decision to Seek Treatment for Symptoms of Acute Myocardial Infarction: An Evaluation of the Self-Regulatory Model of Illness Behaviour. Journal of Psychosomatic Research, 56, 67-73.
https://doi.org/10.1016/S0022-3999(03)00082-5

[35]   Millar, K., Purushotham, A., McLatchie, E., George, W.D. and Murray, G.D. (2005) A 1-Year Prospective Study of Individual Variation in Distress, and Illness Perceptions, after Treatment for Breast Cancer. Journal of Psychosomatic Research, 58, 335-342.
https://doi.org/10.1016/j.jpsychores.2004.10.005

[36]   Gould, R.V., Brown, S.L. and Bramwell, R. (2010) Psychological Adjustment to Gynaecological Cancer: Patients’ Illness Representations, Coping Strategies and Mood Disturbance. Psychology & Health, 25, 633-646.
https://doi.org/10.1080/08870440902811163

[37]   Dempster, M., McCorry, N.K., Brennan, E., Donnelly, M., Murray, L. and Johnston, B.T. (2012) Psychological Distress among Survivors of Esophageal Cancer: The Role of Illness Cognitions and Coping. Disease of the Esophagus, 25, 222-227.
https://doi.org/10.1111/j.1442-2050.2011.01233.x

[38]   Carlisle, A.C.S., John, A.M.H., Fife-Show, C. and Lloyd, M. (2005) The Self-Regulatory Model in Women with Rheumatoid Arthritis: Relationships between Illness Representations, Coping Strategies and Illness Outcome. British Journal of Health Psychology, 10, 571-587.
https://doi.org/10.1348/135910705X52309

[39]   Di Mattei, V.E., Bisceglie, A.R., Sigismondi, C., Mangili, G., Prunas, A. and Sarno, L. (2010) Analisi della domanda e dei bisogni psicologici in un reparto di ginecologia oncologica. Psicologia della Salute, 3, 131-144.

[40]   Paschali, A.A., Hadjulis, M., Papadimitriou, A. and Karademas, E.C. (2015) Patient and Physician Reports of the Information Provided about Illness and Treatment: What Matters for Patients’ Adaptation to Cancer during Treatment? Psycho-Oncology, 24, 901-909.
https://doi.org/10.1002/pon.3741

 
 
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