GSC  Vol.1 No.3 , August 2011
Highly Regio-Selective Synthesis of β-Amino Alcohol by Reaction with Aniline and Propylene Carbonate in Self Solvent System over Large Pore Zeolite Catalyst
Abstract: The nucleophilic ring opening of epoxides with amines is a well known route for the synthesis of β-amino alcohols. The use of carbonates offers significant advantages over epoxides as they are far less hazardous materials, safe for handling, do not require high-pressure equipment and most notably the possibility of solvent less reactions. In this work, utilization of zeolite as host catalyst in the reaction media for synthesis of β-amino alcohols without using solvent is reported.
Cite this paper: nullA. Kinage, P. Upare, A. Shivarkar and S. Gupte, "Highly Regio-Selective Synthesis of β-Amino Alcohol by Reaction with Aniline and Propylene Carbonate in Self Solvent System over Large Pore Zeolite Catalyst," Green and Sustainable Chemistry, Vol. 1 No. 3, 2011, pp. 76-84. doi: 10.4236/gsc.2011.13013.

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