Received 13 June 2016; accepted 19 August 2016; published 22 August 2016
A severe trauma patient is a patient with a violent trauma, whatever visible lesions  . Severe traumas are a public health problem. They are the main causes of death of patients under 40 years old in France  . The management of severe trauma is multidisciplinary, based upon an optimal assessment of the lesions.
Medical imaging, especially the whole body computed tomography plays an important role in assessing severe trauma lesion immediately stable or stabilized by appropriate resuscitation  . The pre-hospital clinical evaluation of trauma patients is well codified and based on Vittel criteria that define a severe trauma patient. These criteria, supposing to lead to the whole body scan are often used differently, leading to several behaviors    .
In presence of the large number of tests carried out with or without clinical signs and the expensive nature of the whole body scanner, we then conducted this study so as to appreciate the contribution of test in the management of severe trauma.
2. Patients and Methods
Our retrospective and analytical study lasted 14 months (from July 2013 to August 2014). It took place in the radiology department of Armentieres hospital centre in France. It involved the analysis of computed tomography reports and emergency department results of severe trauma patients immediately stable at the entrance or stabilized after receiving a whole body scan.
Were included, severe trauma patients with stable entering or stabilized who received a full body scanner. Were excluded from the study, severe trauma patients with stable entering or stabilized who received a full body scanner, but the emergency records were not usable because insufficiently informed.
Firstly, we have established a list of severe trauma patients from computerized records (PACS: Picture Archiving and Communication System) of the hospital’s radiology department with as search criteria “Body scanner”. Secondly we have recovered the summary sheets of the transfer to the emergency of these patients, that we have exploited. The presence of at least one of the criteria of Vittel (Table 1) was sufficient to consider the patient as a severe trauma justifying the achievement of a full body scanner.
Clinical examination was considered as negative in the absence of clinical signs or other symptoms related to traumatism. It was considered positive in the presence of a symptomatology or clinical signs related to trauma- tism.
The tests were performed using helical scanner of 64 slide brand General Electric CT 660 OPTIMA.
Table 1. List of criteria Vittel  .
Scanner data were recorded through the report of the radiologist. The CT scans that have shown a discrepancy with the clinic were reviewed by a senior radiologist to identify missed lesions during the first interpretation. Only the original traumatic lesions were identified.
The scanner was considered as positive when it is mentioned in the radiological report a traumatic appearance lesion at the considered level.
Data were processed with SPSS Version 20.0 and Excel 2013 software. The radio-clinical correlation was determined using the Kappa coefficient controlled by a confidence interval of 95%  . The Kappa coefficient was interpreted according to Landis and Koch data  , as indicated in Table 2.
During the survey period, 180 patients that is 58.33% of men (n = 105) and 41.67% women (n = 75) were searched. The average age of patients was 32.71 years old with some extremes of 3 and 98 years old.
The highway accident predominated in 90% of injuries (n = 162). The high kinetic was the main reason that motivated the realization of a whole body scanner.
The medical transport was the most requested and performed in 34.4% of cases by firefighters, followed by the Emergency and Resuscitation Mobile Service in 28.9% of cases.
Severe trauma status was observed in 155 patients that is 86.11% of the cases and had at least a Vittel criterion. This status was deemed subjective in 24 patients (13.33%).
One hundred and twelve patients (62.2%) had at least a clinical sign. The predominant clinical sign was pain, more frequent at the thoracic level in 28.9% of cases.
The computed tomography lesions searched by segments are reported in Table 3 and was dominated by rib fractures and pulmonary parenchymal contusions.
Table 2. Interpretation of kappa coefficient correlation.
Table 3. Division of scanographic lesions per segments scanned.
*ED: extra-dural, SD: subdural, IP: intra-parenchymal.
These computed tomography scan tests were performed within 1 or 2 hours with some extra-times of 15 minutes and 24 hours after the patient arrival in the emergency unit.
After the completion of the whole body scan, 144 (80%) injured patients were allowed to return home and 34 (18.9%) of them had received hospital treatment in a specialized service. Two patients (1.1%) were transferred to the Regional University Hospital Centre.
The average radiation dose received by patients was 3319.21 mGy.cm with some extremes of 2482 and 4920 mGy・cm.
The radio-clinical correlation is shown in Table 4. In the fragmented analysis by level, the group corresponding to asymptomatic patients with a normal scanner was the most represented (56.7% to 90.6%). This proportion decreased to 34.4% when we grouped the different segments.
Patients with at least one clinical sign and a normal scanner were in majority, all level mixed (38.9%). This percentage decreased slightly at each stage or level with variable percentages of 6.7% to 33.9%.
The Table 5 describes the radio-clinical concordance/correlation according to the Kappa coefficient. The correlation between clinical sign and computed tomography lesions was poor all level mixed. It varied from “bad” and “average” according to the level. The best correlation was recorded at the pelvic level.
The goals of this study were globally achieved even though it has some limitations mainly related to its mono- centric nature and to a prior selection of patients transported in priority to the Regional University Hospital Centre.
Table 4. Clinical and scanographic correlation.
*: +/+: Positive clinical and scan at the considered level; +/−: Positive clinical examination and negative scan at the considered level; −/+: Negative clinical examination and positive scan at the considered level; −/− Negative clinical examination and scan at the considered level. **All segments mixed.
Table 5. Interpretation of the radio-clinical correlation according to Kappa coefficient.
We also note the biases inherent to retrospective studies, including inadequate intelligence data but mainly the mode of inclusion of severe trauma patients from the list of full body scanners made for emergencies in the base of the radiology department data. This method of inclusion sets aside the patients who underwent a full body scanner registered under another name in the computer base of Radiology.
The assessment of the benefit-risk balance of the whole body scanner protocol in terms of morbidity and mortality is limited by the lack of information on the fate of long-term patients.
However, this study has the merit of having allowed us to evaluate the relationship between clinical and scan globally through the kappa coefficient correlation, even if it is not the criterion choice to determine the interest of the systematic whole body scanner in our study’s population.
The average age of our study’s population was relatively young that is 32.71 years old (extremes 3 - 98 years old) with a male predominance (sex ratio: 1.4). At Marseille in France, CHAUMOITRE et al. got similar results, that is an average age of 34 year old in 2009  . BABAUD et al. in 2012 had noticed an average age of 35.06 years old (extremes 15 - 88 years old)  . This finding could be related to the hyperactivity of men in general and youth in particular. The average age of patients in this study is lower than that reported in the literature; this could be explained by the inclusion of the pediatric population that has been excluded from the other studies above cited.
The highway accidents represent 90% of severe trauma causes in our study. These results are superimposed to those obtained in 2010 by TURK et al. as well as OBERLIN et al. in 2013 with respectively 64% and 60% of highway accidents   . The highway accidents are dominated by car accidents that represented 70.6% in this study and following the same lines with the literature data namely 53% for OBERLIN et al. in Grenoble and 80% for SALIM et al. in Poitiers   . The high kinetic was the most frequent Vittel criterion that is 76.6% of the study population. This only reason demanded a whole body scanner, even in the absence of clinical signs.
Most severe trauma patients (81.6%) are taking to emergency unit by a medical transport, in order of frequency, by the firefighters (34.4%), the Emergency and Resuscitation Service (28.9%) and by the private ambulances (18.3%). The need for transportation by emergency medical units is directly related to the gravity/severity initially estimated by the accident mechanism and its potential lesion.
The issue of medical transport is to respect the concept of the “Golden Hour” to optimize the treatment in the first hour so as to stabilize the patient  . Despite this urgency, a significant number of patients in our series were transported to the emergency unit by an unsafe vehicle (6.1%). This could be explained by the relative severity of the trauma of these patients.
The high kinetic was the most common severity criterion, its evaluation is often subjective because it is sometimes a personal assessment of a medical team member, or of emergency unit who witnessed the damage of the vehicle or an assessment of the place of the fall. The questioning sometimes difficult, doesn’t always clarify the circumstances of the accident, mainly in absence of witnesses, in case of emotional shock or unconsciousness. In our study, 86.11% of patients had at least one Vittel criterion against 13.33% in which the assessment of severity criteria was subjective. Our results are significantly higher than those obtained by OBERLIN et al. in 2013 in Grenoble (France) who had found 51.5% of objective criteria against 40.5% subjective criteria in his study  .
One hundred and twelve patients (62.2%) had at least one clinical sign. Our figures are lower than those obtained by OBERLIN et al. who found 85% of patients with symptoms over a population of 429 patients  . It is the same for TURCK et al. who recorded 75.6% of patients with symptoms over a population of 140 patients  . Thirty-one patients (17.2%) had a positive clinical examination at the cerebral level, 75 at the spine (41.7%), 27 at the thoracic (15%), 29 at the abdominal level (16.1%) and 17 at the pelvis level (9.4%). These results are in the same line with those of OBERLIN et al. in the brain, spinal and pelvic level respectively 17.9%, 44.5% and 16.8 of clinical signs over 429 patients  . The tendency reversed at thoracic and abdominal level with respectively 44.5% and 37.8% of clinical signs. This difference in tendency would probably relate to the lack of clinical examination, sedation, analgesics and or to the alcoholization of these patients.
Only 48 patients (26.7%) had a lesion in the computed tomography based on Vittel criteria. Our results are close to those obtained by BABAUD et al. in 2012, who found over 164 of whole body scan performed only 32.3% of abnormal computed tomography on the presence of Vittel criteria. According to BABAUD et al., the proportion of abnormal whole body scanner is significantly higher in the group of patients who received a targeted scan than those who received a justified whole body scanner only by the presence of Vittel criterion  . On the other hand, HELLER et al. in 2014 got, out of 481 whole body scanner oriented by anamnesis and clinic, only 1.5% of lesions with only minor traumas lesion  . Our figures are lower than those obtained by OBERLIN et al., who found in their multifaceted study 55.8% of computed tomography lesions in a population of 429 patients based on TRENAU classification who correct the parameters of Vittel criteria  . It is the same for TURCK et al. who recorded 65% of computed tomography lesions in 123 patients selected thanks to ISS score (Injury Severity Score)  . This static difference could be explained by the choice of scores or algorithm in the assessment of severity criteria in trauma patients during the pre-hospital sorting on the one hand and of the reputation of the Hospital centre study on the other hand. We notice that there is more abnormality in the scan using other criteria than those of Vittel as the ISS score. This score is limited to the most three serious injuries in three areas; it does not take into account the other less serious lesions or multiple lesions in the same areas. Vittel Criteria are responsible for an over sorting of serious trauma patients. They include patients with no serious element in the clinical examination. Out of 180 patients surveyed, only two had respiratory distress and 80% of them are directly discharged from the emergency department. This could also be explained by the proximity of the Regional University Hospital Centre (20 km, that is 20 min to our survey center) where patients in need of urgent and specific care are first taken to. The direct consequence of this practice is the low number of injuries recorded in our study and the return home of the majority of trauma patients (80%) after performing the whole body scanner. Nevertheless 18.9% of patients were hospitalized in a specialized unit for monitoring or for special care. However, TILLOU et al. as well as TURK et al. had recorded respectively 27% and 10% of patients who were returned home after being checked-up in emergencies ward   .
In the fragmented analysis by level, the group corresponding to asymptomatic patients with a normal scanner is the most represented (56.7% to 90.6%), which is not in favor of the whole body scanner. Contrariwise, this proportion decreases to 34.4% when we group together the various segments. In other words, this means 34.4% of the whole body scanner could not have been realized. Patients with at least one clinical sign and a normal scanner were the most represented all level mixed together (38.9%), but this proportion decreased slightly at each level with a varying percentage between 6%, 7% to 33.9%. This therefore, results that the performance of a targeted scanner would be more beneficial for these patients. The correlation between the clinical signs and the computed tomography lesions was poor all level mixed. OBERLIN et al. have found a poor global correlation.
At cerebral level, the correlation was poor (0.242), with 8 computed tomography lesions out of 23 symptomatic patients for this level. One asymptomatic patient had an injury type of oedema-hemorrhagic contusion. This lesion is small in our study. This observation is comparable to that of TURCK et al. who found 100% of a VPN compared to CT that we compare to the gold standard diagnosis  . According to STIELL et al., minor cranial traumas do not require scanner if their conscience to the Glasgow Coma Score is 15, if they do not vomit more than once if they have no signs of skull fracture. Thus, it is probably necessary to perform a brain CT to stable trauma patients whose clinical examination is totally negative, namely, no initial loss of consciousness, a Glasgow Coma Score at 15, no pupil abnormality, no headache, no trace of cranial impact  . Figure 1 shows an extra dural hematoma that was symptomatic.
Figure 1. Cerebral scan without iodinated contrast injection: Axial-parenchymal window cut showing a spontaneous hyper density right temporal extra axial, bi-convex lens corresponding to an extra-dural hematoma right temporal (a star) in front of a fracture line (put a bone window and show) (b, arrow), and a mass effect on the right lateral ventricle (a, double arrows).
The correlation is poor at the spine level (0.178) contrary to TURCK et al. or OBERLIN et al. results who had found mediocre correlation   . Some stable vertebral fractures are found and required some immobilization. The conventional radiographies in our study could have at least detected some of these lesions but their long and difficult performance does not seem compatible with the taking care of our patients. We then believe that the scanner of the thoracolumbar spine could be systematic. Figure 2 illustrates asymptomatic unstable cervical spinal fracture.
At Thoracic level the correlation is also poor (0.384) with maximum asymptomatic lesions namely pulmonary contusion, rib fractures and pneumothorax. These results are comparable to those obtained by TURCK et al. or OBERLIN et al.   . DEUNK et al. have demonstrated that there was no prognostic difference between severe trauma patients with occult pulmonary contusions and those who did not  . YADAV et al. as well have demonstrated in a meta-analysis in 2010, that there was no difference in mortality and the stay duration between the treated occult pneumothorax and those only monitored including mechanical ventilation  . Thus, the chest occult lesions could probably have gone unnoticed without a major prognostic.
At the abdomen, the clinical examination is unreliable, with a poor radio-clinical correlation. Even though we have recorded at the scanner only one lesion of splenic contusion, 8 our result is superimposed on the one of TURCK et al. or OBERLIN et al.   (Figure 3). The management of these lesions has been changed by the introduction of an increased monitoring.
The best correlation was found at the pelvic level. This could be explained by the fact that pelvic fractures show violent traumas. The diagnosis of pelvic fracture in a conscious patient (whole body scanner > 13) is easy and the negative clinical examination allows in these patients to limit unnecessary cliché made by the negative clinical examination because it is an expressive injuries due to the anatomy of the pelvic ring that has some weak areas  .
Figure 2. Cervical Scan without iodinated contrast injection: Axial bone window cut showing a right corporeo-laminar fracture of C3, unstable look (arrows).
Figure 3. Abdominal scan with injection of iodinated contrast agent (portal phase): axial parenchymal window cut showing a small home of splenic contusion (full arrow), with discrete subcapsular hematoma (open arrow) from the vascular pedicle distance.
The comparison of an oriented segmental strategy by clinical has a systematic whole body scanner strategy that has been made in several studies to severe trauma in general. TILLOU et al. found when systematically realizing the whole body scanner, 17% of unsuspected lesions by the traumatology team  . In the study of DEUNK et al., 242 patients out of 465 had at least one additional lesion discovered on the whole body scanner regarding a segmental strategy based on the clinical and standard cliché  . This finding is probably related to the lack of clinical examination, sedation, analgesics and or alcoholization of those patients that could influence the clinical examination. WEDEGARTNER et al. have shown that the oriented segmental scanner by clinical would permit an irradiation up to three times lower  .
The average dose received by patient is 3319.21 mGy.cm with a maximum irradiation of 4920.06 mGy・cm and a minimum of 2482.65 mGy・cm. BABAUD obtained some (dose-length product) values similar to that of our study that is a cumulative average (dose-length product) of 3283.31 mGy・cm. These values (figures) are up to the reference levels established by the Institute of Radiation Protection and Nuclear Safety (IRSN)  . In our study, 34.4% of asymptomatic patients have a negative scanner. This is a significant number of scanners that could have been avoided even if occult lesions were found (10%), based on a good questioning and a thorough clinical examination of the patient, the occult lesions recorded were of minor severity. Those patients had unnecessary radiation and sometimes beyond the recommended doses.
The systematic performance of the whole body scanner based on Vittel criteria in severe trauma patients causes an over sorting and a poor clinical and computed tomography correlation. The results of this study call to reflect on the use of these Vittel criteria that could be refined to reduce the number of normal examinations carried out. The additional use of clinical data could make that improvement.
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