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 JCDSA  Vol.6 No.4 , September 2016
Reviscometer Evaluation of the Skin Condition after Applying Retinol and Vitamin C Complex in Menopausal Women
Abstract: Background: Topical application of retinol connected with the improvement of various parameters of aging skin is often used in post- and menopausal women. Vitamin A - vitamin C complex treatments may influence skin surface lipids and boost the fibroblasts activity as well as increase their number, thus inducing the improvement of its elasticity. Objective: In the current paper, we demonstrate and evaluate the impact of retinol and vitamin C complex on the face and neck skin elasticity level in a group of women aged 50 - 69. Method: Reviscometer RVM 600 (Courage & Khazaka, Germany) was used to measure forehead, cheeks and neck skin elasticity in a group of 21 women. Each of the patients was subjected to four treatment sessions that included skin elasticity measurements before each of the three retinol peels at 3-week intervals and one 3-week after the completion of the therapy. Results: Significant increase in the cheeks and neck skin elasticity was observed in the study group. Conclusion: Treatments including retinol with vitamin C - vitamin A complex significantly influence the improvement of skin elasticity, thus reducing the signs of skin aging.
Cite this paper: Wójcik, A. , Bartnicka, E. and Rotsztejn, H. (2016) Reviscometer Evaluation of the Skin Condition after Applying Retinol and Vitamin C Complex in Menopausal Women. Journal of Cosmetics, Dermatological Sciences and Applications, 6, 148-155. doi: 10.4236/jcdsa.2016.64019.
References

[1]   Sherratt, M.J. (2009) Tissue Elasticity and the Ageing Elastic Fibre. Age, 31, 305-325.
http://dx.doi.org/10.1007/s11357-009-9103-6

[2]   Wójcik, A. and Rotsztejn, H. (2012) The Influence of Hormones on Skin Lipids in Women during Menopause. Rev Menopausal, 1, 41-44.

[3]   Rona, C., Vailati, F. and Berardesca, E. (2004) The Cosmetic Treatment of Wrinkles. Journal of Cosmetic Dermatology, 3, 26-34.
http://dx.doi.org/10.1111/j.1473-2130.2004.00054.x

[4]   Sorg, O., Antille, C., Kaya, G. and Saurat, J.H. (2006) Retinoids in Cosmeceuticals. Dermatologic Therapy, 19, 289-296.
http://dx.doi.org/10.1111/j.1529-8019.2006.00086.x

[5]   Varani, J., Warner, R.L., Gharaee-Kermani, M., et al. (2000) Vitamin A Antagonizes Decreased Cell Growth and Elevated Collagen-Degrading Matrix Metalloproteinases and Stimulates Collagen Accumulation in Naturally Aged Human Skin. Journal of Investigative Dermatology, 114, 480-486.
http://dx.doi.org/10.1046/j.1523-1747.2000.00902.x

[6]   Kafi, R., Kwak, H.S., Schumacher, W.E., et al. (2007) Improvement of Naturally Ages Skin with Vitamin A (Retinol). Archives of Dermatology, 143, 606-612.
http://dx.doi.org/10.1001/archderm.143.5.606

[7]   Rossetti, D., Kielmanowicz, M.G., Vigodman, S., Hu, Y.P., Chen, N., et al. (2011) A Novel Anti-Ageing Mechanism for Retinol: Induction of Dermal Elastin Synthesis and Elastin Fibre Formation. International Journal of Molecular Sciences, 33, 62-69.
http://dx.doi.org/10.1111/j.1468-2494.2010.00588.x

[8]   Sorg, O., Tran, C. and Saurat, J.H. (2001) Cutaneous Vitamins A and E in the Context of UV or Chemically Induced Oxidative Stress. Skin Pharmacology, 14, 363-372.
http://dx.doi.org/10.1159/000056370

[9]   Ligade, V.S., Sreedhar, D., Manthan, J. and Udupa, N. (2009) Cosmeceuticals: Are They Truly Worth the Cost? Indian Journal of Dermatology, Venereology and Leprology, 75, 8-9.
http://dx.doi.org/10.4103/0378-6323.45213

[10]   Hausman, E. (1967) Cofactor Requirements for the Enzymatic Hydroxylation of Lysine in a Polypeptide Precursor of Collagen. Biochimica et Biophysica Acta, 133, 591-593.
http://dx.doi.org/10.1016/0005-2795(67)90566-1

[11]   Caygill, J.C. (1969) Prevention of Tropocollagen Aggregation by L-Ascorbicacid. Biochimica et Biophysica Acta, 181, 334-336.
http://dx.doi.org/10.1016/0005-2795(69)90260-8

[12]   Lobo, V., Patil, A., Phatak, A. and Chandra, N. (2010) Free Radicals, Antioxidants and Functional Foods: Impact on Human Health. Pharmacognosy Reviews, 4, 118-126.
http://dx.doi.org/10.4103/0973-7847.70902

[13]   Paye, M., Mac-Mar, S., Elkhayat, A., Tarrit, C., Mermet, P. and Humbert, P.H. (2013) Use of the Reviscometer for Measuring Cosmetics-Induced Skin Surface Effects. Skin Research and Technology, 13, 343-349.
http://dx.doi.org/10.1111/j.1600-0846.2007.00236.x

[14]   Murakami, M., Tanno, O. and Kurokawa, H. (2009) Evaluation of Skin Mechanical Properties by Determining of Resonant Frequency and Loss Resistance with Tactile Sensor. Skin Research and Technology, 1, 125-126.

[15]   Anderson, B.D. and Raykar, P.V. (1989) Solute Structure-Permeability Relationships in Human Stratum Corneum. Journal of Investigative Dermatology, 93, 280-286.
http://dx.doi.org/10.1111/1523-1747.ep12277592

[16]   Bell, T.V., Herley, C.B., Stetsko, D., et al. (1987) Expression of mRNA Homologous to Interleukin 1 in Human Epidermal Cells. Journal of Investigative Dermatology, 88, 375-379.
http://dx.doi.org/10.1111/1523-1747.ep12469041

[17]   Fisher, G.J., Wang, Z.Q., Datta, S.C., et al. (1997) Pathophysiology of Premature Skin Aging Induced by Ultraviolet Light. The New England Journal of Medicine, 337, 1419-1428.
http://dx.doi.org/10.1056/NEJM199711133372003

[18]   Kim, S.J. and Won, Y.H. (1998) The Effect of Glicolic Acid on Cultured Human Skin Fibroblasts: Cell Proliferative Effect and Increased Collage Syntehesis. The Journal of Dermatology, 25, 85-89.

[19]   Okano, Y., Abe, Y., Masaki, H., Santhanam, U., Ichihashi, M., Fanasaka, Y., et al. (2003) Biological Effects of Glycolic Acid on Dermal Matrix Metabolism Mediated by Dermal Fibroblasts and Epidermal Keratinocytes. Experimental Dermatology, 12, 57-63.
http://dx.doi.org/10.1034/j.1600-0625.12.s2.9.x

[20]   Nusgens, B.V., Humbert, P. and Rougier, A. (2001) Topically Applied Vitamin C Enhances the mRNA Level of Collagens I and III, Their Processing Enzymes and TIMP1 in the Human Dermis. Journal of Investigative Dermatology, 116, 853-859.
http://dx.doi.org/10.1046/j.0022-202x.2001.01362.x

[21]   Pinnell, S.R. (2003) Cutaneous Photodamage, Oxidative Stress, and Topical Antioxidant Protection. Journal of the American Academy of Dermatology, 48, 1-19.
http://dx.doi.org/10.1067/mjd.2003.16

[22]   Padayatty, S.J., Katz, A., Wang, Y., et al. (2003) Vitamin C as an Antioxidant: Evaluation of Its Role in Disease Prevention. Journal of the American College of Nutrition, 22, 18-35.
http://dx.doi.org/10.1080/07315724.2003.10719272

[23]   Seité, S., Bredoux, C., Compan, D., et al. (2005) Histological Evaluation of a Topically Applied Retinol-Vitamin C Combination. Skin Pharmacology and Physiology, 18, 81-87.
http://dx.doi.org/10.1159/000083708

 
 
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