ABSTRACT The present study was performed to clarify the influence of having a firm purpose in life (PIL) on psychological and physical stresses. Participants were 59 subjects (19 males and 40 fe- males) with a mean age of 30.9 years (standard deviation, 12.1; range, 18 - 68 years). We used a mental arithmetic (MA) test as a goaloriented stressor; the test was supposed to be finished before a time limit expired without using pencil and paper. We used a PIL test to assess the intensity of personal meaning in one’s life, an interest in mental arithmetic test (IMAT) to assess the intensity of interest in the MA test, and an anxiety inventory (AI) to assess the anxiety level of before and during the MA test. Heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP) and nose tip temperature (NTT) were recorded before and after MA. We used logistic regression modeling to estimate the odds ratio (OR) of independent variables of age, sex, PIL test score, AI score, HR, SBP, DBP, and NTT before the MA test. Multivariate-adjusted models showed that PIL test scores prior to the MA test significantly predicted the observed changes in AI score and HR. Other variables were not significant predictors. In conclusion, we found that a firm PIL decreased anxiety under psychological stress as measured with the MA test, even with objective evaluation by others. Having a firm PIL also lowered the response of the sympathetic nervous system to psych0logical stress.
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nullIshida, R. , Abe, T. and Okada, M. (2011) Firmness of purpose in life significantly influences emotional state and autonomic nervous activity. Health, 3, 507-511. doi: 10.4236/health.2011.38084.
 Smith, E.E., Nolen-Hoeksema, S., Fredrickson, B.K. and Loftus, G.R. (2003) Atkinson & Hilgard’s introduction to psychology. Thomson.
Atkinson, R.L., Atkinson, R.C., Smith, E.E., Ben, D.J. and Nolen-Hosksema, S. (1996) Hilgard’s introduction to psychology. Harcourt Brace College Publishers, Fort Worth.
Frankl, V.E. (1972) The meaning of meaninglessness: A challenge to psychotherapy. American Journal of Psychoanalysis, 32, 85-89. doi:10.1007/BF01872487
Bundra, A. (1977) Social learning theory. Prentice Hall, Upper Saddle River.
Ishida, R. and Okada, M. (2006) Effects of a firm pur- pose in life on anxiety and sympathetic nervous activity caused by emotional stress: Assessment by psycho-phy- siological method. Stress and Health, 22, 275-281.
Agbu, J.F. (2010) Type A behavior pattern: A new insight to gender challenges in higher education. Psychology, Health & Medicine, 15, 528-539.
Hemingway, H., Shipley, M., Brunner, E., Britton, A., Malik, A. and Marmot, M. (2005) Does autonomic function link social position to coronary risk? Circulation, 111, 3071-3077.
Atanackovic, D., Schulze, J., kr?ger, H., Brunner-Wei- nzierl, M.C. and Deter, H.C. (2003) Acute psychological stress induces a prolonged suppression of the production of reactive oxygen species by phagocytes. Journal of Neuroimmunology, 142, 159-165.
Crumbaugh, J.C. and Maholic, L.T. (1964) An experimental study in existentialism: The psychometric approach to Frankl’s concept of noogenic neurosis. Journal of Clinical Psychology, 20, 200-207.
Sato, F. and Tanaka, H. (1974) An experimental study on the existential aspect of life: Part I. Tohoku Psychologica Folia. 33, 20-46.
Ishida, R. (2008a) Correlation between social desirability and autonomic nervous function under goal-oriented stress (mental arithmetic) with consideration of parental attitude (in Japanese). Autonomic Nervous System, 45, 242-249.
Smith, E.E., Nolen-Hoeksema, S., Fredrickson, B.L. and Loftus, G.R. (2003) Atkinson & Hilgard’s introduction to psychology. Thomson.
Tannno, K., Sakata, K., Ohsawa, M., Onoda, T., Itai, K., Yaegashi, Y. and Tamakoshi, A. (2009) Association of ikigai as a positive psychological factor with all-cause mortality and cause-specific mortality among middle- aged and elderly Japanese people: Finding from the Ja- pan collaborative cohort study. Journal of Psychoso- matic Research, 67, 67-75.
Willls, L.P. and Schnellmann, R.G. (2011) Telomeres and telomerase in renal health. Journal of the American Soci- ety of Nephrology, 22, 39-41.
Ben-Porath, I. and Weinberger, R.A. (2005) The signals and pathways activating cellular senescence. The International Journal of Biochemistry & Cell Biology, 37, 961-976. doi:10.1016/j.biocel.2004.10.013
Bartholomew, J.N. and Galbiati, F. (2010) Mapping of oxidative stress response elements of the caveolin-1 pro- moter. Methods in molecular biology, 594, 409-423.
Ishii, N., Ishii, T. and Hartman, P.S. (2007) The role of the electron transport SDHC gene on lifespan and cancer. Mitochondrion, 7, 24-28. doi:10.1016/j.mito.2006.11.012
Stefano, G.B., Bianchi, E., Guarma, M., Fricchione, G.L., Zhu, W., Cadet, P., Mantione, K.J., Casares, F.M., Kream, R.M. and Esch, T. (2007) Nicotine, alcohol and cocaine coupling to reward processes via endogenous morphine signaling: The dopamine-morphine. Medical Science Mo- nitor: International Medical Journal of Experimental and Clinical Research, 13, 91-102.
Xu, X., Aron, A., Brown, L., Cao, G., Feng, T. and Weng, X. (2011) Reward and motivation system: A brain mapping study of early-stage intense romantic love in Chinese participants. Human Brain Mapping, 32, 249-257.
Hegadoren, K.M., O’Donnell, T., Lanius, R., Coupland, N.J. and Lacaze-Masmonteil, N. (2009) The role of beta- endorphin in the pathophysiology of major depression. Neuropeptides, 43, 341-353.
Spanagel, R., Herz, A., Bals-Kubik, R. and Shippenberg, T.S. (1991) Beta-endorphin-induced locomotor stimulation and reinforcement are associated with an increase in dopamine release in the nucleus accumbens. Psychopharmacology, 104, 51-56. doi:10.1007/BF02244553
Touyz, R.M. and Briones, A.M. (2011) Reactive oxygen species and vascular biology: Implications in human hypertension. Hypertension Research, 34, 5-14.