Right Ventricular Endomyocardial Fibrosis in Neonate—A Case Report

Ramachandran  Muthiah

doi:10.4236/crcm.2016.55032

Ramachandran Muthiah

Abstract: Endomyocardial fibrosis is characterized by the formation of fibrous tissue in the endocardium. Although the disease may affect both ventricles, isolated or not, the right ventricle is more frequently involved. Endocardial fibrosis may be present in the entire ventricular cavity, being usually more marked in the apical region and right ventricular inflow tract. Its etiology, however, still remains unknown. Background—Reports on endomyocardial fibrosis in pediatric patients are not common. It is more frequent from the fourth year of age on, with few reports in the first 2 years of life. This case aimed at reporting right ventricular endomyocardial fibrosis in 7 days old male neonate, in addition to discussing the etiopathogenesis and future perspective of the disease.

Keywords: Apical Fibrosis, Right Ventricle, Tricuspid Regurgitation, Echocardiography, Neonate

Cite this paper: Muthiah, R. (2016) Right Ventricular Endomyocardial Fibrosis in Neonate—A Case Report. Case Reports in Clinical Medicine, 5, 170-175. doi: 10.4236/crcm.2016.55032.

References

[1] Schoen, F.J. and Mitchell, R.N. (2010) Robbins and Cotran, Pathologic Basis of Disease. Chap. 12, 8th Edition, Saunders, Philadelphia, 577.

[2] Bukhman, G., Ziegler, J. and Parry, E. (2008) Endomyocardial Fibrosis, Still a Mystery after 60 Years. Achieve of Public Library of Science (PLOS) Neglected Tropical Diseases, 2, e97.
http://dx.doi.org/10.1371/journal.pntd.0000097

[3] Shaper, A.G. (1970) The Geographical Distribution of Endomyocardial Fibrosis. Indian Journal of Pathology and Microbiology (Basel), 35, 26-35.
http://dx.doi.org/10.1159/000162195

[4] Gergana, M.-S., Eivgeny, H., Ami, N., Cecilia, G.M., Dario, C.G. and Alon, S. (2009) Prevalence of Exclusively Right-Sided Endomyocardial Fibrosis among Patients with Heart Failure in Equatorial Guinea. The Open Tropical Medicine Journal, 2, 24-26.
http://dx.doi.org/10.2174/1874315300902010024

[5] Falase, A.O. (1983) Endomyocardial Fibrosis in Africa. Postgraduate Medical Journal, 59, 170-178.
http://dx.doi.org/10.1136/pgmj.59.689.170

[6] Yin, R. (2000) Endomyocardial Fibrosis in China, Chinese Medical Sciences Journal, 15, 55-60.

[7] Williams, A.W., Ball, J.D. and Davies, J.N. (1954) Endomyocardial Fibrosis in Africa, Its Diagnosis, Distribution and Nature. Transactions of the Royal Society of Tropical Medicine and Hygiene, 48, 290-305.
http://dx.doi.org/10.1016/0035-9203(54)90100-5

[8] Connor, D.H., Somers, K., Hutt, M.S., Manion, W.C. and D’Arbela, P.G. (1968) Endomyocardial Fibrosis in Uganda (Davies’ Disease), Part II, an Epidemiologic, Clinical, and Pathologic Study. American Heart Journal, 75, 107-124.
http://dx.doi.org/10.1016/0002-8703(68)90122-1

[9] Corssmit, E.P., Trip, M.D. and Durrer, J.D. (1999) Loffler’s Endomyocarditis in the Idiopathic Hypereosinophilic Syndrome. Cardiology, 91, 272-276.
http://dx.doi.org/10.1159/000006923

[10] Davies, J., Spry, C.J., Vijayaraghavan, G. and De Souza, J.A. (1983) A Comparison of the Clinical and Cardiological Features of Endomyocardial Disease in Temperate and Tropical Regions. Postgraduate Medical Journal, 59, 179-185.
http://dx.doi.org/10.1136/pgmj.59.689.179

[11] Kartha, C.C. (1995) Endomyocardial Fibrosis, a Case for the Tropical Doctor. Cardiovascular Research, 30, 636-643.
http://dx.doi.org/10.1016/S0008-6363(96)88509-9

[12] Olsen, E.G.J. and Sekiguchi, M. (1990) Morphological Overview and Pathogenic Mechanisms in Endomyocardial Fibrosis—Associated with Eosinophilia. Cardiomyopathy Update, 3, 21.

[13] Davies, J.N. (1968) The Ridge in Endomyocardial Fibrosis. The Lancet, 1, 631-632.
http://dx.doi.org/10.1016/S0140-6736(68)91250-6

[14] Mocumbi, A.O., Ferreira, M.B., Sidi, D. and Yacoub, M.H. (2008) A Population Study of Endomyocardial Fibrosis in a Rural Area of Mozambique. New England Journal of Medicine, 359, 43-49.
http://dx.doi.org/10.1056/NEJMoa0708629

[15] Brockington, I.F., Olsen, E.G. and Goodwin, J.F. (1967) Endomyocardial Fibrosis in Europeans, Resident in Tropical Africa. The Lancet, 1, 583-588.
http://dx.doi.org/10.1016/S0140-6736(67)90440-0

[16] Mocumbi, A.O. (2008) Epidemiology, Pathogenesis and Management of Endomyocardial Fibrosis. PhD Thesis, Imperial College, London.

[17] Farrer-Brown, G., Tarbit, M.H., Somers, K. and Hutt, M.S.R. (1972) Microvascular Study of Hearts with Endomyocardial Fibrosis. British Heart Journal, 34, 1250-1262.
http://dx.doi.org/10.1136/hrt.34.12.1250

[18] Seth, S., Thatai, D., Sharma, S., Chopra, P. and Talwar, K.K. (2004) Clinico-Pathological Evaluation of Restrictive Cardiomyopathy (Endomyocardial Fibrosis and Idiopathic Restrictive Cardiomyopathy) in India. Europeon Journal of Heart Failure, 6, 723-729.
http://dx.doi.org/10.1016/j.ejheart.2003.11.009

[19] Sovari, A.A., Morita, N., Weiss, J.N. and Karagueuzian, H.S. (2008) Serum Transforming Growth Factor-β1 as a Risk Stratifier of Sudden Cardiac Death. Journal of Medical Hypotheses and Ideas, 71, 262-265.

[20] Mocumbi, A. (2009) Neglected Cardiomyopathies in Africa. South African Heart Journal, 6, 30-41.

[21] Berensztein, C.S., Pineiro, D., Marcotegui, M., Brunoldi, R., Blanco, M.V. and Lernan, J. (2000) Usefulness of Echocardiography and Doppler Echocardiography in Endomyocardial Fibrosis. Journal of American Society of Echocardiography, 16, 385-392.
http://dx.doi.org/10.1016/S0894-7317(00)70008-3

[22] Davies, J.N. (1969) The African Cardiomyopathies. Annals of the New York Academy of Sciences, 156, 498-503.
http://dx.doi.org/10.1111/j.1749-6632.1969.tb16747.x

[23] Iglezias, S.D., Benvenuti, L.A., Calabrese, F., Salemi, V.M., Silva, A.M., Carturan, E., De Oliveira, S.A., Thiene, G. and De Brito, T. (2008) Endomyocardial Fibrosis: Pa-thological and Molecular Findings of Surgically Resected Ventricular Endomyocardium. Virchows Archiv, 453, 233-241.
http://dx.doi.org/10.1007/s00428-008-0652-3

[24] Chelo, D., Nguefack, F., Mbassi Awa, H.D. and Kingue, S. (2016) Endomyocardial Fibrosis in Sub Saharan Africa-The Geographical Origin, Socioeconomic Status, and Dietary Habits of Cases Reported in Yaounde, Cameroon. Annals of Pediatric Cardiology, 8, 202-209.