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 IJCM  Vol.7 No.4 , April 2016
Perioperative Nursing Management of an Animal Model of Axial Flow Blood Pump Implantation
Abstract: This study aimed to explore the characteristics of perioperative nursing of experimental goats using self-made axial-flow blood pump implantation and provided theoretical nursing knowledge and practice-based evidence for the clinical application of domestically manufactured artificial cardiac pumps. Methods: Seven experimental goats were used in this study, three for pre-testing and four for the formal experiments. According to the surgical requirements for axial-flow blood pump implantation into the cardiac apex, we creatively designed and made a series of highly practical animal surgical instruments including a composite disassemblable bed for experimental animal transferring and monitoring, a multifunctional animal surgery bed, and portable medical supporting equipment. We also applied for two national invention patents and one utility model patent. Active measures were taken to ensure careful preparation before surgery, close collaboration during surgery, and effective management of complications after surgery. Results: Two of the four experimental goats died during surgery because of a massive hemorrhage caused by distal anastomotic failure and air embolism-induced cardiac arrest caused by air leakage from the outlet into the heart due to poor connection of the auxiliary pressure tap (used to measure left ventricular pressure). The mean survival time of the remaining three experimental goats was 22.7 hours. Conclusion: This study was the first to systematically and comprehensively investigate the perioperative nursing management of axial-flow blood pump implantation using animal models. These findings could greatly promote further clinical applied nursing research of self-made artificial cardiac pump implantation in experimental goats.
Cite this paper: Kang, A. , Li, J. , Zhou, Y. , Hu, L. , Qiu, Z. and Zhou, X. (2016) Perioperative Nursing Management of an Animal Model of Axial Flow Blood Pump Implantation. International Journal of Clinical Medicine, 7, 270-279. doi: 10.4236/ijcm.2016.74029.
References

[1]   El Banayosy, A., Fey, O., Sarnowski, P., et al. (2001) Midterm Follow up of Patients Discharged from Hospital under Left Ventricular Assistance. Journal of Heart and Lung Transplantation, 20, 53-58.

[2]   McCarthy, P.M. (1995) Heart Mate Implantable Left Ventricular Assist Device: Bridge to Transplantation and Future Applications. The Annals of Thoracic Surgery, 59, 46-51.

[3]   Bank, A.J., Mir, S.H., Nguyen, D.Q., et al. (2000) Effects of Left Ventricular Assist Devices on Outcomes in Patients Undergoing Heart Transplantation. The Annals of Thoracic Surgery, 69, 1369-1374.

[4]   Hsu, R.B., Chu, S.H. and Chien, C.Y. (2000) Heart Mate Left Ventricular Assist Device for Long-Term Circulatory Support. Journal of the Formosan Medical Association, 99, 336-340.

[5]   Koul, B., Solem, J.O., Steen, S., et al. (1998) Heart Mate Left Ventricu1ar Assist Device as Bridge to Heart Transplantation. The Annals of Thoracic Surgery, 65, 1625-1630.

[6]   Rogers, J.G., Butler, J., Lansman, S.L., et al. (2007) Chronic Mechanical Circulatory Support for Inotrope-Dependent Heart Failure Patients Who Are Not Trans-Plant Candidates: Results of the Intrepid Trial. Journal of the American College of Cardiology, 50, 741-747.
http://dx.doi.org/10.1016/j.jacc.2007.03.063

[7]   Patel, S.M., Throckmorton, A.L., Untaroiu, A., et al. (2005) The Status of Failure and Reliability Testing of Artificial Blood Pumps. ASAIO Journal, 51, 440-451.
http://dx.doi.org/10.1097/01.mat.0000169083.90253.3c

[8]   Farrar, D.J., Bourque, K., Dague, C.P., et al. (2007) Design Features, Developmental Status, and Experimental Results with the Heartmate Ⅲ Centrifugal Left Ventricular Assist System with a Magnetically Levitated Rotor. ASAIO Journal, 53, 310-315.
http://dx.doi.org/10.1097/MAT.0b013e3180536694

[9]   Wieselthaler, G.M.O., Driscoll, G., Jansz, P., et al. (2010) Initial Clinical Experience with a Novel Left Ventricular Assist Device with a Magnetically Levitated Rotor in a Multiinstitutional Trial. Journal of Heart and Lung Transplantation, 29, 1218-1225.
http://dx.doi.org/10.1016/j.healun.2010.05.016

[10]   Morshuis, M., Schoenbrodt, M., Nojiri, C., et al. (2010) Dura Heart Magnetically Levitated Centrifugal Left Ventricular Assist System for Advanced Heart Failure Patients. Expert Review of Medical Devices, 7, 173-183.
http://dx.doi.org/10.1586/erd.09.68

[11]   Zhang, Y., Hu, S.S., Zhou, J.Y., et al. (2009) The Study of FW Type of Axial Flow Pump in Vitro Hemolysis and Animal Experiment. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 16, 114-117. (In China)

[12]   Wu, G.H. (2004) The Axial Heart Assist Device and Its Current Development Situation. Beijing Biomedical Engineering, 23, 306-308. (In China)

[13]   Liu, Y.X. and Han, S.F. (2007) The Application Progress of Animal Experiment in Nursing Research. Family Nurse, 5, 1-3. (In China)

[14]   Tao, L., Zhou, X. and Zhang, Z.J. (2012) The Manufacture and Application of the Portable Medical Equipment Belt for Clinic. Chinese Medical Equipment Journal, 33, 28-29. (In China)

[15]   Li, G.R., Zhu, X.D. and Tian, B.S. (2008) The Study of the Structure and Hydrodynamic Characteristics of the Miniature Apex-Axial Pump. Chinese Medical Equipment Journal, 29, 3-5. (In China)

[16]   Zhou, X., Tao, L. and Kang, A.M. (2013) The Analysis of Three Death Cases of Goats in the Left Ventricular Assist Device Experiment. Medical & Pharmaceutical Journal of Chinese People’s Liberation Army, 25, 46-50. (In China)

[17]   Zhou, X., Tao, L. and Zhang, Z.J. (2013) The Manufacture of Animal-Transporting Care Beds with Detachability and Composability. Chinese Medical Equipment Journal, 34, 28-29. (In China)

[18]   Zhou, X., Kang, A.M. and Tao, L. (2013) The Manufacture and Application of Multifunctional Animal-Operating Beds. Medical & Pharmaceutical Journal of Chinese People’s Liberation Army, 25, 43-45. (In China)

[19]   Tao, L., Zhou, X. and Kang, A.M. (2013) The New Concept of Left Ventricular Assist Device Experiment on Animals. Medical & Pharmaceutical Journal of Chinese People’s Liberation Army, 25, 39-42. (In China)

[20]   Qu, Z. (2008) The Modern Mechanical Circulatory Support in the Treatment of Heart Failure. Scientific and Technical Documentation Press, Beijing, 2-7. (In China)

[21]   Rao, V., Slater, J.P., Edwards, N.M., Naka, Y. and Oz, M.C. (2011) Surgical Management of Valvular Disease in Patients Requiring Left Ventricular Assist Device Support. The Annals of Thoracic Surgery, 71, 1448-1453.
http://dx.doi.org/10.1016/S0003-4975(01)02479-1

[22]   Zhai, Q.X., Huang, L.J., Ha, H.X., Jia, L. and Gou, P. (2007) The Maintenance and Management of Animal Clean Operating Room. Laboratory Animal Science, 24, 43-44. (In China)

[23]   Kang, A.M., Zhou, X. and Hu, L. (2013) The Nursing and Enlightenment during the Perioperative Period in Laboratory Goats Implanted II Axial Flow Artificial Blood Pump. Journal of Nursing, 20, 41-43. (In China)

[24]   Tao, J. and Pei, D.J. (2008) The Nursing of Chronic Heart Failure Patients with the Implantation of Cardiac Resynchronization Therapy Device. Journal of Nursing, 15, 42-43. (In China)

[25]   Kang, A.M. and Zhou, X. (2013) Seven Cases of Nursing of Laboratory Goats with the Implantation of Axial Flow Artificial Blood Pump. Medical & Pharmaceutical Journal of Chinese People’s Liberation Army, 8, 55-57. (In China)

[26]   Ding, N. and Xu, C.Y. (2006) Five Cases of Intensive Care of Patients with LVAD Device Implantation. Nursing Research, 20, 1266-1267. (In China)

[27]   Wang, N., et al. (2010) The Management of Laboratory Animal Based on Animal Benefits. Progress in Veterinary Medicine, 31, 148-152. (In China)

[28]   Yang, X. (2010) The Primary Research of the Noise Controlling in Intensive Care Unit of Hospitals. Master’s Thesis, Taiyuan University of Science and Engineering, 40. (In China)

[29]   Kang, A.M., Zhou, X. and Hu, H. (2013) The Management of the Implantation of LVAD in Goats. Chinese Journal of Comparative Medicine, 23, 42-44. (In China)

 
 
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