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 AiM  Vol.6 No.5 , April 2016
Phylogenetic Analysis of Frequent Recombinant Region in Micropeptin Biosynthetic Gene Cluster among the Genus Microcystis
Abstract: The gene cluster for the biosynthetic of a nonribosomal peptide, cyanopeptolins and micropeptin (MCN), was identified in Microcystis strains and halogenated MCN-producing Microcystis were found to possess the halogenase gene, mcnD, between nonribosomal peptide synthetase genes, mcnC and mcnE. A comparative sequence analysis of the mcn gene cluster between halogenated and non-halogenated MCN-producing strains revealed mosaic sequence traces from mcnD in the non-coding region between mcnC and mcnE in the latter strains. A phylogenetic analysis based on a 170-bp non-coding region including the mcnD traces suggests that the recombination events occurred in a particular region of the Microcystis’ mcn gene. This study provides novel insight into the ecological patterning of widespread Microcystis species.
Cite this paper: Nishizawa, T. , Miura, T. , Futamura, A. , Shirai, M. (2016) Phylogenetic Analysis of Frequent Recombinant Region in Micropeptin Biosynthetic Gene Cluster among the Genus Microcystis. Advances in Microbiology, 6, 368-373. doi: 10.4236/aim.2016.65035.
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