OJI  Vol.6 No.1 , March 2016
Proteomics and Its Applications in Diagnosis of Auto Immune Diseases
Abstract: Although the proteomics and its applications in detecting autoimmune diseases are a prominently discussed issue, this review will focus particularly some prominent aspects regarding clinical utility of these techniques in prognosis, diagnosis, and treatment of these diseases. The impact of immunofluorescent techniques, enzyme immunoassays and use of proteomics biomarkers in the characterization of the auto immune diseases is briefly discussed. The necessity of adopting existing technologies of protein chemistry, predisposition testing, targeted monitoring and prevention of diseases through nutrition coupled with life changes will be focused as modern diagnostic tools in realizing the changeover from isolated medicine to personalized medicine. Use of biological fluids, in order to identify low abundance proteins as biomarkers in detecting autoimmune diseases is attempted in the study of serum/plasma proteomics.
Cite this paper: Gebretsadik, G. and Menon, M. (2016) Proteomics and Its Applications in Diagnosis of Auto Immune Diseases. Open Journal of Immunology, 6, 14-33. doi: 10.4236/oji.2016.61003.

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