dures are performed using an anterior approach. Autologous graft and osteosynthesis might be necessary.

Despite bone lysis, we opted in our case for a conservative treatment, given minimal neurological disorders and normal spine morphology. The result was satisfactory. According to Alberto Di Martino and colleagues in Italy, conservative treatment is the main attitude adopted today in the treatment of spondylitis [16] .

4. Conclusion

Spinal involvement of Histoplasma duboisii is rare. It can simulate Pott’s disease at all stages of his diagnosis. The definitive diagnosis is made on mycological and pathological examination. In the absence of significant neurological deficit and spinal instability, conservative treatment provides a good outcome.

Conflict of Interest

No funds were received in support of this study.

NOTES

*Corresponding author.

Cite this paper
N’Dri Oka, D. , Mbende, A. and Sissoko, D. (2016) Spinal Cord Compression Caused by Multifocal Histoplasmosis Treated Conservatively: Case Report and Literature Review. Open Journal of Modern Neurosurgery, 6, 20-24. doi: 10.4236/ojmn.2016.61004.
References
[1]   Vorhauer, R., Brière, J., Passa, P. and Chelloul, N. (1976) Diagnostic histologique de l’histoplasmose à “grandes formes”. à propos de deux observations. Arch Anat Cytol Pathol., 6, 463-467.

[2]   Debrie, J.C., Thomas, J., Menard, M., Quiniou, M. and Salaun, J.J. (1981) Laryngeal Histoplasmosis Caused by Histoplasma duboisii. Dakar Med, 26, 26-32.

[3]   Musoke, F. (2001) Spinal African Histoplamosis Simulating Tuberculous Spondylitis. African Health Sciences, 1, 28- 29.

[4]   Minta, D.K., Sylla, M., Traoré, A.M., et al. (2014) Première observation malienne d’histoplasmose africaine disséminée à prédominance osseuse chez un enfant VIH négatif. Revue de la littérature. Journal de Mycologie Médicale, 24, 152-157.
http://dx.doi.org/10.1016/j.mycmed.2013.08.001

[5]   Camain, R., Berthe, M., Klefstad-Sillonville, F., et al. (1958) Sept nouveaux cas d’histoplasmose observés en AOF. Bulletin de la Société de Pathologie Exotique, 1, 83-107.

[6]   Drexler, L. (1968) L’aspect radiologique de l’histoplasmose africaine. Annales de la Societe Belge de Medecine Tropicale, 6, 607-612.

[7]   Gentilini, M. (1995) Mycoses profondes. Médecine Tropicale, 3, 268-288.

[8]   Gentilini, M., Brucker, G., Danis, M., et al. (1980) Dix cas d’histoplasmose: Aspects cliniques, biologiques et thérapeutiques. Annales de Médecine Interne, 4, 209-212.

[9]   Chandenier, J., Gomad, D., Moyen, G., et al.(1995) Histoplasmose africaine à Histoplasma capsulatum var. duboisii: Liens avec le SIDA. à propos de cas congolais récents. Cahiers Santé, 5, 227-234.

[10]   André, C., Badoual, J., Kalifa, G. and Dubousset, J. (1984) Histoplasmose africaine: Une observation. Archives Francaises de Pédiatrie, 41, 429-431.

[11]   Peloux, Y., Camain, R., Courson, B. and Quenum, C. (1965) L’histoplasmose. Médecine Tropicale, 4, 439-445.

[12]   N’Dri Oka, D., Varlet, G., Kakou, M., et al. (2001) Spondylodiscite à Histoplasma duboisii: A propos de deux observations et revue de la littérature. Neurochirurgie, 47, 431-434.

[13]   Tazi, E.M., Essadi, I., Serraj, K., et al. (2009) Histoplasmose sacrée dix ans après un lymphome non hodgkinien du sacrum: A propos d’un cas. Cancer/Radiothérapie, 13, 337-339.
http://dx.doi.org/10.1016/j.canrad.2009.03.004

[14]   Carme, B., Hayette, M.P., Itoua-Ngaporo, A., Ngolet, A., et al. (1993) Histoplasmose africaine à Histoplasma duboisii (histoplasma capsulatum var. duboisii): Quatorze cascongolais observés en 10 ans (1981-1990). Journal de Mycologie Médicale, 3, 67-73.

[15]   Collomb, H., Camain, R., Courson, B. and Quenum, C. (1962) Paraplégie aigue par ostéolyse due à Histoplasma capsulatum variété duboisii. Bulletin de la Société de Pathologie Exotique, 5, 753-756.

[16]   Di Martino, A., Papapietro, N., Lanotte, A., et al. (2012) Spondylodiscitis: Standards of Current Treatment. Current Medical Research & Opinion, 28, 689-699.
http://dx.doi.org/10.1185/03007995.2012.678939

 
 
Top