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 AID  Vol.5 No.4 , December 2015
BCG Infection after Bladder Cancer Treatment—3 Clinical Case Reports
Joana Alves1, Angélica Ramos2,3, Teresa Carvalho2, Susana Silva1, João Tiago Guimarães2,3,4, António Sarmento1
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Abstract: Immunotherapy with Bacillus Calmette-Guérin (BCG) to treat non-muscle invasive bladder cancer has become an effective and superior alternative to chemotherapy. Intravesical treatment with BCG appears to be relatively safe; however, occasionally BCG infection complicates such treatment. In the present work we describe three patients in whom BCG infection occurred after intravesical BCG therapy. All patients had positive urine culture forMycobacterium tuberculosis complex, using AccuProbe culture identification and then Genotype Mycobacterium MTBC test identified Mycobacterium bovis BCG. The diagnosis is difficult and microbiologic study is usually negative, so high index of suspicion is essential.
Keywords: Bacillus Calmette-Guérin, Intravesical BCG Therapy, BCG Infection, Disseminated M. bovis BCG Infection
Cite this paper: Alves, J. , Ramos, A. , Carvalho, T. , Silva, S. , Guimarães, J. , Sarmento, A. , (2015) BCG Infection after Bladder Cancer Treatment—3 Clinical Case Reports. Advances in Infectious Diseases, 5, 218-221. doi: 10.4236/aid.2015.54027.
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http://dx.doi.org/10.1128/JCM.01595-10

 
 
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