Plexiform Neurofibroma of Nasal Tip
Author(s)
Rajanala Venkata Nataraj,
Mohan Jagade,
Kartik Parelkar,
Reshma Hanawte,
Arpita Singhal,
Dev Rengaraja,
Kiran Kulsange,
Kartik Rao,
Pallavi Gupta
Affiliation(s)
Department of Ear, Nose & Throat and Head & Neck Surgery, Grant Government Medical College, Mumbai, India.
Department of Ear, Nose & Throat and Head & Neck Surgery, Grant Government Medical College, Mumbai, India.
ABSTRACT
Neurogenic tumor is the name given to any tumor that arises from the nerve tissue or its coverings. Neurogenic tumors of Sino-nasal cavity are a very rare entity. The most common types are Schwannomas and Neurofibromas and the plexiform subtype is one form of these neuroendocrine tumors. We report the case series of two such cases of a plexiform neurofibroma of the nasal tip, which were excised via an open rhinoplasty approach.
Neurogenic tumor is the name given to any tumor that arises from the nerve tissue or its coverings. Neurogenic tumors of Sino-nasal cavity are a very rare entity. The most common types are Schwannomas and Neurofibromas and the plexiform subtype is one form of these neuroendocrine tumors. We report the case series of two such cases of a plexiform neurofibroma of the nasal tip, which were excised via an open rhinoplasty approach.
Cite this paper
Nataraj, R. , Jagade, M. , Parelkar, K. , Hanawte, R. , Singhal, A. , Rengaraja, D. , Kulsange, K. , Rao, K. and Gupta, P. (2015) Plexiform Neurofibroma of Nasal Tip. International Journal of Otolaryngology and Head & Neck Surgery, 4, 423-428. doi: 10.4236/ijohns.2015.46068.
Nataraj, R. , Jagade, M. , Parelkar, K. , Hanawte, R. , Singhal, A. , Rengaraja, D. , Kulsange, K. , Rao, K. and Gupta, P. (2015) Plexiform Neurofibroma of Nasal Tip. International Journal of Otolaryngology and Head & Neck Surgery, 4, 423-428. doi: 10.4236/ijohns.2015.46068.
References
[1] New, G. and Devine, K. (1947) Neurogenic Tumors of Nose and Throat. Archives of Otolaryngology, 46, 163-179.
http://dx.doi.org/10.1001/archotol.1947.00690020172004 [2] DasGupta, T., Brasfield, R., Strong, E. and Hajdu, S. (1969) Benign Solitary Schwannoma (Neurilemomas). Cancer, 24, 355-360.
http://dx.doi.org/10.1002/1097-0142(196908)24:2<355::AID-CNCR2820240218>3.0.CO;2-2 [3] Rameh, C., Husseini, S., Tawil, A., Fuleihan, N. and Hadi, U. (2007) Solitary Plexiform Neurofibroma of the Nasal Tip: Case Report and Review of the Literature. International Journal of Pediatric Otorhinolaryngology Extra, 2, 116-119.
http://dx.doi.org/10.1016/j.pedex.2007.03.003 [4] Verocay, J. (1908) Multiple Geschwulste als Systemerkrankung am nervosen Apparate. Festschrift fur Chiari, Wien and Leipzig, 378. [5] Hillstrom, R.P., Zarbo, R.J. and Jacobs, J.R. (1990) Nerve Sheath Tumors of the Paranasal Sinuses: Electron Microscopy and Histopathologic Diagnosis. Otolaryngology Head and Neck Surgery, 102, 257-263. [6] Berlucchi, M., Piazza, C., Blanzuoli, L., Battaglia, G. and Nicolai, P. (2000) Schwannoma of the Nasal Septum: A Case Report with Review of the Literature. European Archives of Oto-Rhino-Laryngology, 257, 402-405.
http://dx.doi.org/10.1007/s004050000242 [7] Ferner, R. and O’Doherty, M. (2000) Neurofibroma and Schwannoma. Current Opinion in Neurology, 15, 679-684.
http://dx.doi.org/10.1097/00019052-200212000-00004 [8] Wilson, J., McLaren, K., MdIntyre, M., von Haacke, N. and Maran, A. (1988) Nerve Sheath Tumors of the Head and Neck. Ear, Nose & Throat Journal, 67, 103-110. [9] Lemmerling, M., Moerman, M., Govaere, F., Praet, M., Kunnen, M. and Vermeersch, H. (1998) Schwannoma of the Tip of the Nose: MRI. Neuroradiology, 40, 264-266.
http://dx.doi.org/10.1007/s002340050582 [10] Donnelly, M., Al-Sader, M. and Blayney, A. (1992) View from Beneath: Pathology in Focus, Benign Nasal Schwannoma. Journal of Laryngology and Otology, 106, 1011-1015.
http://dx.doi.org/10.1017/S0022215100121644
[1] New, G. and Devine, K. (1947) Neurogenic Tumors of Nose and Throat. Archives of Otolaryngology, 46, 163-179.
http://dx.doi.org/10.1001/archotol.1947.00690020172004 [2] DasGupta, T., Brasfield, R., Strong, E. and Hajdu, S. (1969) Benign Solitary Schwannoma (Neurilemomas). Cancer, 24, 355-360.
http://dx.doi.org/10.1002/1097-0142(196908)24:2<355::AID-CNCR2820240218>3.0.CO;2-2 [3] Rameh, C., Husseini, S., Tawil, A., Fuleihan, N. and Hadi, U. (2007) Solitary Plexiform Neurofibroma of the Nasal Tip: Case Report and Review of the Literature. International Journal of Pediatric Otorhinolaryngology Extra, 2, 116-119.
http://dx.doi.org/10.1016/j.pedex.2007.03.003 [4] Verocay, J. (1908) Multiple Geschwulste als Systemerkrankung am nervosen Apparate. Festschrift fur Chiari, Wien and Leipzig, 378. [5] Hillstrom, R.P., Zarbo, R.J. and Jacobs, J.R. (1990) Nerve Sheath Tumors of the Paranasal Sinuses: Electron Microscopy and Histopathologic Diagnosis. Otolaryngology Head and Neck Surgery, 102, 257-263. [6] Berlucchi, M., Piazza, C., Blanzuoli, L., Battaglia, G. and Nicolai, P. (2000) Schwannoma of the Nasal Septum: A Case Report with Review of the Literature. European Archives of Oto-Rhino-Laryngology, 257, 402-405.
http://dx.doi.org/10.1007/s004050000242 [7] Ferner, R. and O’Doherty, M. (2000) Neurofibroma and Schwannoma. Current Opinion in Neurology, 15, 679-684.
http://dx.doi.org/10.1097/00019052-200212000-00004 [8] Wilson, J., McLaren, K., MdIntyre, M., von Haacke, N. and Maran, A. (1988) Nerve Sheath Tumors of the Head and Neck. Ear, Nose & Throat Journal, 67, 103-110. [9] Lemmerling, M., Moerman, M., Govaere, F., Praet, M., Kunnen, M. and Vermeersch, H. (1998) Schwannoma of the Tip of the Nose: MRI. Neuroradiology, 40, 264-266.
http://dx.doi.org/10.1007/s002340050582 [10] Donnelly, M., Al-Sader, M. and Blayney, A. (1992) View from Beneath: Pathology in Focus, Benign Nasal Schwannoma. Journal of Laryngology and Otology, 106, 1011-1015.
http://dx.doi.org/10.1017/S0022215100121644