IJOHNS  Vol.4 No.6 , November 2015
Treatment Outcomes in Head and Neck Cancer Patients 80 Years Old and over
ABSTRACT
Background: With the recent aging of society, the need for medical treatment of elderly patients with head and neck cancer seems to have been increasing. Method: The present study analyzed all 103 patients with head and neck cancer ≥80 years, and we compared results with those of the previous generation (Group P; range: 75 - 79 years) comprising 104 patients treated in the same period. Results: We provided treatment just as wanted and could not choose it often. The reasons were oncological factors such as unresectable tumor or distant metastasis, refusal of treatment, and physical factors such as poor PS or number of comorbidities. Conclusion: Treatment choices should be based on the wishes and motivations of the patient and the medical assessment of physical function. When a patient ≥80 years old is treated, the high incidence of complications and severity of the disease should be considered.

Cite this paper
Terada, T. , Uwa, N. , Sagawa, K. , Mohri, T. , Saeki, N. , Kida, K. , Tsuzuki, K. and Sakagami, M. (2015) Treatment Outcomes in Head and Neck Cancer Patients 80 Years Old and over. International Journal of Otolaryngology and Head & Neck Surgery, 4, 401-408. doi: 10.4236/ijohns.2015.46065.
References
[1]   World Health Organization (WHO) in Internet, World Health Statistics 2014, Mortality and Burden of Disease, by Life Expectancy.
http://apps.who.int/ghodata/

[2]   Suzuki, M., Matayoshi, N., Hasegawa, M., et al. (2008) Treatment Outcomes in Head and Neck Cancer Patients Aged 80 or over. Japanese Journal of Head and Neck Cancer, 34, 594-599.
http://dx.doi.org/10.5981/jjhnc.34.594

[3]   Monden, S., Nishikawa, K., Morishita, T., et al. (2003) Head and Neck Cancer Treatment in the Elderly—Evaluation and Management of Complications. Nippon Jibiinkoka Gakkai Kaiho, 106, 7-16.
http://dx.doi.org/10.3950/jibiinkoka.106.7

[4]   Oken, M.M., Creech, R.H., Tormey, D.C., et al. (1982) Toxicity and Response Criteria of the Eastern Cooperative Oncology Group. American Journal of Clinical Oncology, 5, 649-655.
http://dx.doi.org/10.1097/00000421-198212000-00014

[5]   Charlson, M.E., Pompei, P., Ales, K.L., et al. (1987) A New Method of Classifying Prognostic Comorbidity in Longitudinal Studies: Development and Validation. Journal of Chronic Diseases, 40, 373-383.
http://dx.doi.org/10.1016/0021-9681(87)90171-8

[6]   Miller, M.D., Paradis, C.F., Houck, P.R., et al. (1992) Rating Chronic Medical Illness Burden in Geropsychiatric Practice and Research: Application of the Cumulative Illness Rating Scale. Psychiatry Research, 41, 237-248.
http://dx.doi.org/10.1016/0165-1781(92)90005-N

[7]   Milisavljevic, D., Stankovic, M., Zivic, M., et al. (2012) Head and Neck Cancer Surgery in Elderly: Complications and Survival Rate. Collegium Antropologicum, 36, 13-17.

[8]   Van der Schroeff, M.P., Derks, W., Hordijk, G.J., et al. (2007) The Effect of Age on Survival and Quality of Life in Elderly Head and Neck Cancer Patients: A Long-Term Prospective Study. European Archives of Oto-Rhino-Laryngology, 264, 415-422.
http://dx.doi.org/10.1007/s00405-006-0203-y

[9]   Bernardi, D., Barzan, L., Franchin, G., et al. (2005) Treatment of Head and Neck Cancer in Elderly Patients: State of the Art and Guidelines. Critical Reviews in Oncology/Hematology, 53, 71-80.
http://dx.doi.org/10.1016/j.critrevonc.2004.08.001

[10]   Sarini, J., Fournier, C., Lefebvre, J.L., et al. (2001) Head and Neck Squamous Cell Carcinoma in Elderly Patients: A Long Term Retrospective Review of 273 Cases. Archives of Otolaryngology—Head & Neck Surgery, 127, 1089-1092.
http://dx.doi.org/10.1001/archotol.127.9.1089

[11]   Saikawa, M., Ebihara, T. and Yoshidumi, T. (2000) Treatment for Head and Neck Cancer in Patients at the Age of 80 or Older. Journal of the Japan Broncho-Esophagological Society, 51, 93-97.

[12]   Derks, W., Leeuw, R.D., Hordijk, G.J., et al. (2005) Reasons for Non-Standard Treatment in Elderly Patients with Advanced Head and Neck Cancer. European Archives of Oto-Rhino-Laryngology, 262, 21-26.
http://dx.doi.org/10.1007/s00405-004-0744-x

[13]   Statistics Japan in Internet, Ministry of Public Management, Estimate of the Population, by the Population for a Specific Age Group.
http://www.stat.go.jp/index.htm

[14]   Chaïbi, P., Magné, N., Breton, S., et al. (2011) Influence of Geriatric Consultation with Comprehensive Geriatric Assessment on Final Therapeutic Decision in Elderly Cancer Patients. Critical Reviews in Oncology/Hematology, 79, 302-307.
http://dx.doi.org/10.1016/j.critrevonc.2010.08.004

 
 
Top