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 JDM  Vol.5 No.4 , November 2015
Correlations of Body Mass Index, Japan-Defined and IDF-Defined Waist Circumference, Visceral and Subcutaneous Fat Area with Metabolic Parameters in Japanese Patients with Type 2 Diabetes
Hidekatsu Yanai1*, Yuji Hirowatari2
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Abstract: Obesity is included in the definition of metabolic syndrome. However, there are many controversies surrounding the evaluation of obesity such as body mass index (BMI) and waist circumference (WC) in the definition of metabolic syndrome among various populations. To understand precisely how various anthropometric indices of obesity influence metabolic parameters, we studied the correlations of BMI, WC (Japanese criteria), WC (IDF criteria), visceral fat area (VFA), subcutaneous fat area (SFA) and the VFA/SFA ratio with metabolic parameters in patients with type 2 diabetes. The influences of BMI and WC on diastolic blood pressure and HDL-cholesterol were larger than VFA, whereas the influences of visceral fat area on triglyceride, very low-density lipoprotein-cholesterol, C-peptide and high-sensitivity C-reactive protein were larger than BMI and WC. WC (IDF) was the strongest determinant of adiponectin among anthropometric indices. Present study showed significant different associations of BMI, Japan- and IDF-defined WC, VFA, SFA and the VFA/SFA ratio with blood pressure, glucose and lipid metabolism, and adipocytokines in Japanese patients with type 2 diabetes.
Keywords: Body Mass Index, Type 2 Diabetes, Visceral Fat Area, Waist Circumference
Cite this paper: Yanai, H. and Hirowatari, Y. (2015) Correlations of Body Mass Index, Japan-Defined and IDF-Defined Waist Circumference, Visceral and Subcutaneous Fat Area with Metabolic Parameters in Japanese Patients with Type 2 Diabetes. Journal of Diabetes Mellitus, 5, 290-294. doi: 10.4236/jdm.2015.54036.
References

[1]   Marinou, K., Tousoulis, D., Antonopoulos, A.S., Stefanadi, E. and Stefanadis, C. (2010) Obesity and Cardiovascular Disease: From Pathophysiology to Risk Stratification. International Journal of Cardiology, 138, 3-8.
http://dx.doi.org/10.1016/j.ijcard.2009.03.135

[2]   Matsha, T.E., Hassan, M.S., Hon, G.M., Soita, D.J., Kengne, A.P. and Erasmus, R.T. (2013) Derivation and Validation of a Waist Circumference Optimal Cutoff for Diagnosing Metabolic Syndrome in a South African Mixed Ancestry Population. International Journal of Cardiology, 168, 2954-2955.
http://dx.doi.org/10.1016/j.ijcard.2013.03.150

[3]   World Health Organization (1999) Definition, Diagnosis and Classification of Diabetes Mellitus and Its Complications: Report of a WHO Consultation. Part 1: Diagnosis and Classification of Diabetes Mellitus. World Health Organization, Geneva.

[4]   Examination Committee of Criteria for the Metabolic Syndrome in Japan (2005) Definition and the Diagnostic Standard for Metabolic Syndrome—Committee to Evaluate Diagnostic Standards for Metabolic Syndrome. Nihon Naika Gakkai Zasshi, 94, 794-809.
http://dx.doi.org/10.2169/naika.94.794

[5]   Alberti, K.G., Zimmet, P. and Shaw, J. (2006) Metabolic Syndrome—A New World-Wide Definition. A Consensus Statement from the International Diabetes Federation. Diabetes & Metabolism, 23, 469-480.
http://dx.doi.org/10.1111/j.1464-5491.2006.01858.x

[6]   Yanai, H. and Hirowatari, Y. (2015) Different Associations of Body Mass Index and Visceral Fat Area with Metabolic Parameters and Adipokines in Japanese Patients with Type 2 Diabetes. Diabetes & Metabolism, 41, 261-262.
http://dx.doi.org/10.1016/j.diabet.2015.03.008

[7]   Friedewald, W.T., Levy, R.I. and Fredrickson, D.S. (1972) Estimation of the Concentration of Low-Density Lipoprotein Cholesterol in Plasma, without Use of the Preparative Ultracentrifuge. Clinical Chemistry, 18, 499-502.

[8]   Hirowatari, Y., Yoshida, H., Kurosawa, H., Doumitu, K. and Tada, N. (2003) Measurement of Cholesterol of Major Serum Lipoprotein Classes by Anion-Exchange HPLC with Perchlorate Ion-Containing Eluent. Journal of Lipid Research, 44, 1404-1412.
http://dx.doi.org/10.1194/jlr.D300003-JLR200

[9]   Katsuyama, H., Kawaguchi, A. and Yanai, H. (2015) Not Visceral Fat Area But the Ratio of Visceral to Subcutaneous Fat Area Is Significantly Correlated with the Marker for Atherosclerosis in Obese Subjects. International Journal of Cardiology, 179, 112-113.
http://dx.doi.org/10.1016/j.ijcard.2014.10.112

 
 
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