OJOG  Vol.5 No.12 , October 2015
Recurrent Hydatidiform Molar Pregnancy: A Case Report of 5 Consecutive Molar Pregnancies Complicated by HELLP and DIC, and Review of Literature
ABSTRACT
Hydatidiform mole is the most common form of gestational trophoblastic disease. Recurrent molar pregnancies are extremely rare. Herein, we reported the case of a patient with five consecutive molars; four of them were complete mole, and one was partial mole complicated by HELLP syndrome and DIC.
KEYWORDS
HELLP, DIC, BHCG, GA, CVS, AST, ALT, IVF, PGD

Cite this paper
Khaza’leh, F. , Haloub, K. and Freij, M. (2015) Recurrent Hydatidiform Molar Pregnancy: A Case Report of 5 Consecutive Molar Pregnancies Complicated by HELLP and DIC, and Review of Literature. Open Journal of Obstetrics and Gynecology, 5, 731-734. doi: 10.4236/ojog.2015.512102.
References
[1]   Sebire, M.J. and Seckl, M.J. (2008) Gestational Trophoblastic Disease: Current Management Hydatidiform Mole. BMJ, 337, 452-458.
http://dx.doi.org/10.1136/bmj.a1193

[2]   Bagshawe, K.D., Rent, J. and Webb, J. (1986) Hydatiform Mole in England and Wales. The Lancet, 2, 673-677.
http://dx.doi.org/10.1016/S0140-6736(86)90179-0

[3]   Steigrad, S.J. (2003) Epidemiology of Gestational Trophoblastic Diseases. Best Practice & Research: Clinical Obstetrics & Gynaecology, 17, 837-847.
http://dx.doi.org/10.1016/S1521-6934(03)00049-X

[4]   AlMulhim, A.A. (2000) Hydatidiform Mole. JFCM, 7, 57-61.

[5]   Sebri, N.J., Foskett, R.A., Fisher, R.A., Rees, H., Seckl, M. and Newlands, E. (2002) Risk of Partial and Complete Molal Pregnancy in Relationshipto Age. BJOG, 109, 99-102.
http://dx.doi.org/10.1111/j.1471-0528.2002.t01-1-01037.x

[6]   Palmer, R.J., Driscoll, S.G., Rosenberg, L., Berkowitz, R.S., Lurain, J.R., Soper, J., et al. (1999) Oral Contraception Use and Risk of Gestational Trophoblastic Tumours. Journal of the National Cancer Institute, 91, 635-640.

[7]   Moglabely, Y.B., Kircheisen, R., Seoud, M., ElMogharbel, N., Van den Veyver, I. and Slim, R. (1999) Genetic Mapping of Maternal Locus Responsible for Familial Hydatidiform Moles. Human Molecular Genetics, 8, 667-671.
http://dx.doi.org/10.1093/hmg/8.4.667

[8]   Madhudas, C., Khursheed, F. and Srichand, P. (2011) Analysis of Patients with Recurrent Molar Pregnancy. European Journal of biological Sciences.

[9]   Thomas, W., Griffiths, M., Nelson-Piercy, C. and Sinnamon, K. (2012) Pre-Eclampsia before 20-Week Gestation: Diagnosis, Investigation and Management. Clinical Kidney Journal, 5, 597-599.

[10]   Takok, F.H., Koh, S., Ratnam, S.S., et al. (1978) Coagulation and Fibrinolysis in Hydatidiform Molar Pregnancy. BMJ.

 
 
Top