A Microarray Analysis of Parkinson’s Disease: New Clues and Evaluation

Lirong  Huo; Xiaomin  Wang; Yi  He; Xibin  Liang

doi:10.4236/jbm.2015.39009

Lirong Huo^1,2, Xibin Liang³, Yi He², Xiaomin Wang²^*

Abstract: Parkinson’s disease (PD) is complex and most likely results from an unknown combination of genetic and environmental factors. Here, we defined discrete genes (DGs) in a microarray analysis and found that the percentage of DGs versus all analyzable genes correlated with PD progression. Furthermore, this new parameter was also easily used to evaluate the therapeutic effect of high- frequency electro-acupuncture (EA), thus improving symptoms of PD model rats.

Keywords: Parkinson’s Disease, 6-OHDA, Microarray, Discrete Genes, Cortex, Striatum

Cite this paper: Huo, L. , Liang, X. , He, Y. and Wang, X. (2015) A Microarray Analysis of Parkinson’s Disease: New Clues and Evaluation. Journal of Biosciences and Medicines, 3, 55-60. doi: 10.4236/jbm.2015.39009.

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