JCDSA  Vol.5 No.3 , September 2015
Sarcoidosis-Lymphoma Syndrome: A Spectrum of One Disease
Abstract: Lymphoma might occur in association with sarcoidosis or sarcoidosis might be combined with lymphoma, in so called (“sarcoidosis-lymphoma syndrome”). This syndrome is well reported in medical literature. The question, which one starts before is difficult to answer, as in some cases sarcoidosis starts first then is followed by lymphoma but in other cases during the course of lymphoma sarcoid reaction might be seen. In the present report, we describe a case of 60 years male patient that is presented with a rash with classical sarcoid pathology that overtime changes into typical lymphoma ended with death.
Cite this paper: Sharquie, K. , Al-Hayani, R. , Abdulwahhab, W. and Mohammed, A. (2015) Sarcoidosis-Lymphoma Syndrome: A Spectrum of One Disease. Journal of Cosmetics, Dermatological Sciences and Applications, 5, 181-188. doi: 10.4236/jcdsa.2015.53022.

[1]   Joint Statement of the American Thoracic Society (ATS), the European Respiratory Society (ERS) and the World Association of Sarcoidosis and Other Granulomatous Disorders (WASOG) (1999) Statement on Sarcoidosis. American Journal of Respiratory and Critical Care Medicine, 160, 736-755.

[2]   McGrath, D.S., Goh, N., Foley, P.J. and duBois, R.M. (2001) Sarcoidosis: Genes and Microbes-Soil or Seed. Sarcoidosis Vasculitis Diffuse Lung Disease, 18, 149-164.

[3]   King, C.S. and Kelly, W. (2009) Treatment of Sarcoidosis. Disease-A-Month, 55, 704-718.

[4]   Nunes, H., Bouvry, D., Solar, P. and Valeyre, D. (2007) Sarcoidosis. Orphanet Journal Rare Disease, 2, 46.

[5]   Sadek, M.M., Yung, D., Birnie, D.H., Beanlands, R.S. and Nery, P.B. (2013) Corticosteroid Therapy for Cardiac Sarcoidosis: A Systemic Review. Canadian Journal of Cardiology, 29, 1034-1041.

[6]   Goswami, T., Siddique, S., Cohen, P. and Cheson, B.D. (2010) The Sarcoid-Lymphoma Syndrome. Clinical Lymphoma, Myeloma & Leukemia, 4, 241-247.

[7]   Brincker, H. (1986) The Sarcoidosis-Lymphoma Syndrome. British Journal Cancer, 54, 467-473.

[8]   Brinker, H. and Wilbek, E. (1974) The Incidence of Malignant Tumours in Patients with Respiratory Sarcoidosis. British Journal Cancer, 29, 247-251.

[9]   Brincker, H. (1995) Sarcoidosis and Malignancy. Chest, 108, 1472-1474.

[10]   William, D., Timothy, G. and Dirk, M. (2011) Sarcoidosis in Andrews Disease of the Skin, Clinical Dermatology. 11th Edition, Saunders Alsevier, 31, 700-707.

[11]   Karakantza, M., Matutes, E., MacLennan, K., et al. (1996) Association between Sarcoidosis and Lymphoma Revisited. Journal Clinical Pathology, 49, 208-212.

[12]   Cohen, P.R. and Kurzrock, R. (2007) Sarcoidosis and Malignancy. Clinical Dermatology, 25, 326-323.

[13]   Maayan, H., Ashkenazi, Y., Nagler, A. and Izbicki, G. (2011) Sarcoidosis and Lymphoma: Case Series and Literature Review. Sarcoidosis Vascular Diffuse Lung Disease, 28, 146-152.