[1] Kim, E.S. and Mahlberg, P.G. (1997) Immunochemical Localization of Tetrahydrocannabinol (THC) in Cryofixed Glandular Trichomes of Cannabis (Cannabaceae). American Journal of Botany, 84, 336-342.
http://dx.doi.org/10.2307/2446007
[2] Happyana, N., Agnolet, S., Muntendam, R., Van Dam, A., Schneider, B. and Kayse, O. (2013) Analysis of Cannabinoids in Laser-Microdissected Trichomes of Medicinal Cannabis sativa Using LCMS and Cryogenic NMR. Phytochemistry, 87, 51-59.
http://dx.doi.org/10.1016/j.phytochem.2012.11.001
[3] Turner, C.E. and Elsohly, M.A. (1979) Constituents of Cannabis sativa L .16. Possible Decomposition Pathway of Delta-9-Tetrahydrocannabinol to Cannabinol. Journal of Heterocyclic Chemistry, 16, 1667-1668.
http://dx.doi.org/10.1002/jhet.5570160834
[4] Elsohly, M.A. and Slade, D. (2005) Chemical Constituents of Marijuana: The Complex Mixture of Natural Cannabinoids. Life Sciences, 78, 539-548.
http://dx.doi.org/10.1016/j.lfs.2005.09.011
[5] Elbatsh, M.M., Moklas, M.A., Marsden, C.A. and Kendall, D.A. (2012) Antidepressant-Like Effects of Delta (9)-Tetrahydrocannabinol and Rimon Abant in the Olfactory Bulbectomised Rat Model of Depression. Pharmacology Biochemistry and Behavior, 102, 357-365.
http://dx.doi.org/10.1016/j.pbb.2012.05.009
[6] Borgelt, L.M., Franson, K.L., Nussbaum, A.M. and Wang, G.S. (2013) The Pharmacologic and Clinical Effects of Medical Cannabis. Pharmacotherapy, 33, 195-209.
http://dx.doi.org/10.1002/phar.1187
[7] Waldman, M., Hochhauser, E., Fishbein, M., Aravot, D., Shainberg, A. and Sarne, Y. (2013) An Ultra-Low Dose of Tetrahydrocannabinol Provides Cardio Protection. Biochemical Pharmacology, 85, 1626-1633.
http://dx.doi.org/10.1016/j.bcp.2013.03.014
[8] Sirikantaramas, S., Taura, F., Tanaka, Y., Ishikawa, Y., Morimoto, S. and Shoyama, Y. (2005) Tetrahydrocannabinolic Acid Synthase, the Enzyme Controlling Marijuana Psycho Activity, Is Secreted into the Storage Cavity of the Glandular Trichomes. Plant and Cell Physiology, 46, 1578-1582.
http://dx.doi.org/10.1093/pcp/pci166
[9] Li, K., Feng, J.Y., Li, Y.Y., Yuece, B., Lin, X.H., Yu, L.Y., Li, Y.N., Feng, Y.J. and Storr, M. (2013) Anti-Inflammatory Role of Cannabidiol and o-1602 in Cerulein-Induced Acute Pancreatitis in Mice. Pancreas, 42, 123-129.
http://dx.doi.org/10.1097/MPA.0b013e318259f6f0
[10] Massi, P., Solinas, M., Cinquina, V. and Parolaro, D. (2013) Cannabidiol as Potential Anticancer Drug. British Journal of Clinical Pharmacology, 75, 303-312.
http://dx.doi.org/10.1111/j.1365-2125.2012.04298.x
[11] Slatkin, D.J., Doorenbo, N.J., Harris, L.S., Masoud, A.N., Quimby, M.W. and Schiff, P.L. (1971) Chemical Constituents of Cannabis sativa L. Root. Journal of Pharmaceutical Sciences, 60, 1891-1892.
http://dx.doi.org/10.1002/jps.2600601232
[12] Slatkin, D.J., Knapp, J.E., Schiff, P.L., Turner, C.E. and Mole, M.L. (1975) Steroids of Cannabis sativa Root. Phytochemistry, 14, 580-581.
http://dx.doi.org/10.1016/0031-9422(75)85135-1
[13] Latter, H.L., Abraham, D.J., Turner, C.E., Knapp, J.E., Schiff, P.L. and Slatkin, D.J. (1975) Cannabisativine, a New Alkaloid from Cannabis sativa L. Root. Tetrahedron Letters, 16, 2815-2818.
http://dx.doi.org/10.1016/S0040-4039(00)75003-9
[14] Grotenhermen, F. (2002) Review of Unwanted Actions of Cannabis and THC. Cannabis and Cannabinoids. Pharmacology, Toxicology, and Therapeutic Potential. The Haworth Press, Inc., New York.
[15] Hillig, K.W. and Mahlberg, P.G. (2004) A Chemotaxonomic Analysis of Cannabinoid Variation in Cannabis (Cannabaceae). American Journal of Botany, 91, 966-975.
http://dx.doi.org/10.3732/ajb.91.6.966
[16] Hamill, J.D., Parr, A.J., Rhodes, M.J.C., Robins, R.J. and Walton, N.J. (1987) New Routes to Plant Secondary Products. Nature Biotechnology, 5, 800-804.
http://dx.doi.org/10.1038/nbt0887-800
[17] Flores, H.E. and Curtis, W.R. (1992) Approaches to Understanding and Manipulating the Biosynthetic Potential of Plant Roots. Annals of the New York Academy of Sciences, 665, 188-209.
http://dx.doi.org/10.1111/j.1749-6632.1992.tb42584.x
[18] Liu, C., Wang, Y., Guo, C., Ouyang, F., Ye, H. and Li, G. (1998) Enhanced Production of Artemisinin by Artemisia annua L. Hairy Root Cultures in a Modified Inner-Loop Airlift Bioreactor. Bioprocess Engineering, 19, 389-392.
http://dx.doi.org/10.1007/pl00009026
[19] Fisse, J., Braut, F., Cosson, L. and Paris, M. (1981) In Vitro Study of the Organogenetic Capacity of Cannabis sativa L. Tissues: Effect of Different Growth Substances. Plantes Médicinales et Phytothérapie, 15, 217-223.
[20] Wahby, I., Arraez-Roman, D., Segura-Carretero, A., Ligero, F., Caba, J.M. and Fernandez-Gutierrez, A. (2006) Analysis of Choline and Atropine in Hairy Root Cultures of Cannabis sativa L. by Capillary Electrophoresis-Electrospray Mass Spectrometry. Electrophoresis, 27, 2208-2215.
http://dx.doi.org/10.1002/elps.200500792
[21] Wahby, I., Caba, J.M. and Ligero, F. (2013) Agrobacterium Infection of Hemp (Cannabis sativa L.): Establishment of Hairy Root Cultures. Journal of Plant Interactions, 8, 312-320.
http://dx.doi.org/10.1080/17429145.2012.746399
[22] Feeney, M. and Punja, Z.K. (2003) Tissue Culture and Agrobacterium Mediated Transformation of Hemp (Cannabis sativa L.). In Vitro Cellular & Developmental Biology—Plant, 39, 578-585.
http://dx.doi.org/10.1079/IVP2003454
[23] Sujatha, G., Zdravkovic-Korac, S., Calic, D., Flamini, G. and Kumari, B.D.R. (2013) High Efficiency Agrobacterium rhizogenes-Mediated Genetic, Transformation in Artemisia vulgaris: Hairy Root Production and Essential Oil Analysis. Industrial Crops and Products, 44, 643-652.
http://dx.doi.org/10.1016/j.indcrop.2012.09.007
[24] Sevon, N. and Oksman-Caldentey, K.M. (2002) Agrobacterium rhizogenes-Mediated Transformation: Root Cultures as a Source of Alkaloids. Planta Medica, 68, 859-868.
http://dx.doi.org/10.1055/s-2002-34924
[25] Gamborg, O.L., Miller, R.A. and Ojima, O. (1968) Nutrient Requirements of Suspension Cultures of Soybean Root Cells. Experimental Cell Research, 50, 151-158.
http://dx.doi.org/10.1016/0014-4827(68)90403-5
[26] Drozdowska, L. and Rogozinska, J. (1984) Effect of Growth Regulators and Light Conditions on the Morphogenesis of Excised Winter Rape Roots. Bulletin of the Polish Academy of Sciences. Biology, 32, 429-433.
[27] Whitney, P.J. (1996) Hormone Independent Root Organ Cultures of Rye (Secale cereale). Plant Cell, Tissue and Organ Culture, 46, 109-115.
http://dx.doi.org/10.1007/BF00034843
[28] Bhadra, R. and Shanks, J.V. (1997) Transient Studies of Nutrient Uptake, Growth, and Indole Alkaloid Accumulation in Heterotrophic Cultures of Hairy Roots of Catharanthus roseus. Biotechnology and Bioengineering, 55, 527-534.
http://dx.doi.org/10.1002/(SICI)1097-0290(19970805)55:3<527::AID-BIT9>3.0.CO;2-E
[29] Datta, S., Kim, C.M., Pernas, M., Pires, N.D., Proust, H., Tam, T., Vijayakumar, P. and Dolan, L. (2011) Root Hairs: Development, Growth and Evolution at the Plant-Soil Interface. Plant and Soil, 346, 1-14.
http://dx.doi.org/10.1007/s11104-011-0845-4
[30] Liu, C.F., Zhu, J.Y., Liu, Z.L., Li, L., Pan, R.C. and Jin, L.H. (2002) Exogenous Auxin Effects on Growth and Phenotype of Normal and Hairy Roots of Pueraria lobata (Willd.) Ohwi. Plant Growth Regulation, 38, 37-43.
http://dx.doi.org/10.1023/A:1020904528045