JBM  Vol.3 No.6 , June 2015
Analysis and Comparison about the Common Remedy of Respiratory Viruses through Data Mining
ABSTRACT

Respiratory diseases have a large proportion among those various diseases. Among those, the main diseases that we are now dealing with are viruses which have no majority vaccine found: Human Rhinovirus 14 (HRV), Human Coronavirus OC43 (HCoV), Respiratory Syncytial Virus (RSV), and Human Para influenza virus 1(HVJ). Even though the body can cure most of these viruses by itself, there are some incidents which end up with death. Starting an experiment with those reasons, we separated viruses by the basic symptoms and appearances, and by using data mining, we found similarities and differences of various sequences. As a result, having a high frequency, decision tree prove that each sequences are too different from each other, but still decision tree only shows the difference of the sequences. According to apriori algorithm, it could be able to find a remedy which can block amino acid L, Leucine.

KEYWORDS
Rhinovirus, RSV, HVJ, HCoV, Vaccine

Cite this paper
Ham, C. , Jung, H. and Yoon, T. (2015) Analysis and Comparison about the Common Remedy of Respiratory Viruses through Data Mining. Journal of Biosciences and Medicines, 3, 54-59. doi: 10.4236/jbm.2015.36009.
References
[1]   Schijf, M.A., Lukens, M.V., Kruijsen, D., van Uden, N.O.P., Garssen, J., Coenjaerts, F.E.J., van’t Land, B. and van Bleek, G.M. (2013) Respiratory Syncytial Virus Induced Type I IFN Production by pDC Is Regulated by RSV-Infected Airway Epithelial Cells, RSV-Exposed Monocytes and Virus Specific Antibodies. PLoS One, 8, e81695. http://dx.doi.org/10.1371/journal.pone.0081695

[2]   Costello, H.M., Ray, W.C., Chaiwatpongsakorn, S. and Peeples, M.E. (2012) Targeting RSV with Vaccines and Small Molecule Drugs. Infect Disord Drug Targets, 12, 110-128. http://dx.doi.org/10.2174/187152612800100143

[3]   Press, W.H. and Teukolsky, S.A. (2007) Support Vector Ma-chines. In: Numerical Recipes: The Art of Scientific Computing, 3rd Edition, Cambridge University Press, New York.

[4]   Pourrut, X., Kumulungui, B., Wittmann, T., Moussavou, G., Délicat, A., Yaba, P., Nkoghe, D., Gonzalez, J.P. and Leroy, E.M. The Natural History of Ebola virus in Africa. Microbes and Infection, 7, 1005-1014. http://dx.doi.org/10.1016/j.micinf.2005.04.006

[5]   Pourrut, X., Délicat, A., Rollin, P.E., Ksiazek, T.P., Gonzalez, J.P. and Leroy, E.M. Spatial and Temporal Patterns of Zaire Ebolavirus Antibody Prevalence in the Possible Reservoir Bat Species. The Journal of Infectious Diseases, 196, S176-S183. http://dx.doi.org/10.1086/520541

[6]   Shaikh, F.Y., Cox, R.G., Lifland, A.W., Hotard, A.L., Williams, J.V., Moore, M.L. Santangelo, P.J. and Crowe, J.E. (2012) A Critical Phenylalanine Residue in the Respiratory Syncytial Virus Fusion Protein Cytoplasmic Tail Mediates Assembly of Internal Viral Proteins into Viral Filaments and Particles. MBio, 3, e00270-11. http://dx.doi.org/10.1128/mbio.00270-11

 
 
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