MSCE  Vol.3 No.6 , June 2015
Carbohydrate-Derived Organocatalysts for the Reduction of Imines with Trichlorosilane
Author(s) Xin Ge1, Chao Qian2*, Xinzhi Chen2

The backbone of D-glucosamine hydrochloride was fine-tuned and modified by protecting the hydroxyl groups. In order to reduce imines with trichlorosilane, the carbohydrate-derived organocatalysts were prepared and screened. Methyl-4,6-O-benzylidene-2-amino-2-deoxy-α-D-glucopyr anoside was found as the best catalyst. The reduction was proceeded under CHCl3 as solvent at 40?C, affording 68% - 94% yield.

Cite this paper
Ge, X. , Qian, C. and Chen, X. (2015) Carbohydrate-Derived Organocatalysts for the Reduction of Imines with Trichlorosilane. Journal of Materials Science and Chemical Engineering, 3, 48-53. doi: 10.4236/msce.2015.36008.
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