OJOG  Vol.5 No.6 , June 2015
Differences of Asphyxia in Infants of 35 and 36 Weeks Pregnant Women with or without Antenatal Corticosteroids
Abstract: Objective: To identify differences of Asphyxia in infants of 35 - 36 weeks with or without antenatal corticosteroid. Methods: Case control study was done on 35 and 36 weeks of pregnancy mother with threatened preterm labor who received and did not receive corticosteroids. Results: From 106 patients with threatened preterm labour between 35 - 36 gestational age, 53 patients received corticosteroid, and 53 did not receive corticosteroid. Incidence of asphyxia decreased significantly from patients received corticosteroid (34%:58.5%, P = 0.011). Incidence of decreased in patients received corticosteroid compared with patients did not receive corticosteroid (3.8%: 15.1%), but the difference was not significant (P = 0.093). Based on the length of stay at the hospital, babies receiving corticosteroid before delivery have shorter duration of stay (<3 days) with 94.3%: 84.9% (P = 0.224). Conclusion: There is a significant correlation of newborn asphyxia from 35 - 36 gestational weeks with or without corticosteroid treatment (58.5%:34%, P = 0.011).
Cite this paper: Sabarudin, U. , Renardiansyah, T. and Siddiq, A. (2015) Differences of Asphyxia in Infants of 35 and 36 Weeks Pregnant Women with or without Antenatal Corticosteroids. Open Journal of Obstetrics and Gynecology, 5, 360-364. doi: 10.4236/ojog.2015.56052.

[1]   Kambafwile, J.M., Cousens, S., Hansen, T. and Lawn, J.E. (2010) Antenatal Steroids in Preterm Labour for the Prevention of Neonatal Deaths Due to Complications of Preterm Birth. International Journal of Epidemiology, 39, 1122-1133.

[2]   Porto, A.M., Coutinho, I.C., Correia, J.B. and Amorim, M.M. (2011) Effectiveness of Antenatal Corticosteroids in Reducing Respiratory Disorders in Late Preterm Infants: Randomised Clinical Trial. BMJ, 342, d1696.

[3]   Dalziel, R.D. (2013) Antenatal Cortocosteroids for Accelerating Fetal Lung Maturation for Women at Risk of Preterm Birth (Review). Cochrane Collaboration, 3.

[4]   McKinlay, C.J., Crowther, C.A., Middleton, P. and Harding, J.E. (2012) Repeat Antenatal Glucocorticoids for Women at Risk of Preterm Birth: A Cochrane Systematic Review. American Journal of Obstetrics Gynecology, 206, 187-194.

[5]   Bastek, J.A., Langmuir, H., Kondapalli, L.A., Pare, E., Adamczak, J.E. and Srinivas, S.K. (2012) Antenatal Corticosteroids for Late-Preterm Infants: A Decision-Analytic and Economic Analysis. ISRN Obstetrics and Gynecology, 2012, Article ID: 491595.

[6]   Ventolini, G., Neiger, R., Mathews, L., Adragna, N. and Belcastro, M. (2008) Incidence of Respiratory Disorders in Neonates Born between 34 and 36 Weeks of Gestation Following Exposure to Antenatal Corticosteroids between 24 and 34 Weeks of Gestation. American Journal of Perinatology, 2, 79-83.

[7]   Stutchfield, P., Whitaker, R. and Russell, I. (2005) Antenatal Betamethasone and Incidence of Neonatal Respiratory Distress after Elective Caesarean Section: Pragmatic Randomised Trial. BMJ, 331, 662.

[8]   Liggins, G.C. and Howie, R.N. (1972) A Controlled Trial of Antepartum Glucocorticoid Treatment for Prevention of the Respiratory Distress Syndrome in Premature Infants. Pediatrics, 50, 515-525.

[9]   Wapner, R. and Jobe, A.H. (2011) Art and Science, Clinics in Perinatology. Clinics in Perinatology, 38, 529-545.

[10]   Mumdzhiev, H. (2012) The Late Preterm Infants—Time to Put Our Mind. Akush Ginekol (Sofiia), 51, 38-45.

[11]   Ashton, D.M. (2010) Elective Delivery at Less than 39 Weeks. Current Opinion in Obstetrics and Gynecology, 22, 506-510.

[12]   Asztalos, E. (2012) Antenatal Corticosteroids: A Risk Factor for the Development of Chronic Disease. Journal of Nutrition and Metabolism, 2012, Article ID: 930591.

[13]   Talge, N.M., Holzman, C., Van Egeren, L.A., Symonds, L.L., Scheid, J.M., Senagore, P.K., et al. (2012) Late-Preterm Birth by Delivery Circumstance and Its Association with Parent-Reported Attention Problems in Childhood. Journal of Developmental Behavioral Pediatrics, 33, 405-415.