JTR  Vol.3 No.2 , June 2015
The Influence of Various Intervention Types on Treatment Success Rates among Category II Tuberculosis Patients
Abstract: Background: Category II tuberculosis (TB) patients (i.e. re-treatment TB patients) are at an increased risk for defaulting on treatment compared to Category I TB patients. Therefore, extra steps need to be taken to help Category II TB patients follow through with their treatment. The goal of this study was to examine the effectiveness of three different types of interventions to help improve treatment success rates among Category II patients. Materials and Methods: Three different interventions that were implemented among Category II TB patients in the Bardhaman, Hugli, Malda and Murshidabad districts in West Bengal, India, were: 1) setting up group patient provider meetings (PPMs), 2) making home visits and reinforcing the message of full course of treatment, and 3) linking poor TB patients to social welfare schemes (SWSs) to incentivize them to complete treatment. Results: PPMs and SWSs improved treatment success rates among Category II patients. The treatment success rates for patients who received PPMs and patients who received SWSs were 94.2% and 90.7%, respectively, compared to the 74.5% treatment success rate of patients who received no intervention. The effectiveness of home visits, however, depended on the number of home visits the patient received. Conclusion: PPMs and SWSs improve treatment success among Category II TB patients and may easily be incorporated in Directly Observed Treatment, Short-Course programming as feasible ways. A conclusion regarding home visits, however, could not be drawn from this study.
Cite this paper: SenGupta, B. , Burrus, C. , Tirmizi, N. , Rooj, B. , Moshman, H. , Pandey, S. , Jaamaa, G. and Roy, K. (2015) The Influence of Various Intervention Types on Treatment Success Rates among Category II Tuberculosis Patients. Journal of Tuberculosis Research, 3, 43-49. doi: 10.4236/jtr.2015.32006.

[1]   Agarwal, S.P. and Chauhan, L.S. (2005) Tuberculosis Control in India. Directorate General of Health Services, Ministry of Health and Family Welfare, New Delhi.

[2]   Dye, C., Scheele, S., Dolin, P., Pathania, V. and Raviglione, M.C. (1999) The WHO Global Surveillance and Monitoring Project. Global Burden of Tuberculosis: Estimated Incidence, Prevalence, and Mortality by Country. JAMA, 282, 677-686.

[3]   Jaiswal, A., Singh, V., Ogden, J.A., Porter, J.D.H., Sharma, P.P., Sarin, R., et al. (2003) Adherence to Tuberculosis Treatment: Lessons from the Urban Setting of Delhi, India. Tropical Medicine & International Health, 8, 625-633.

[4]   Khatri, G.R. and Frieden, T.R. (2000) The Status and Prospects of Tuberculosis Control in India. International Journal of Tuberculosis and Lung Disease, 4,193-200.

[5]   Chadha, S.L. and Bhagi, R.P. (2000) Treatment Outcome in Tuberculosis Patients Places under Directly Observed Treatment Short Course (DOTS)—A Cohort Study. Indian Journal of Tuberculosis, 47, 155-158.

[6]   Jaggarajamma, K., Sudha, G., Chandrasekaran, V., Nirupa, C., Thomas, A., Santha, T., et al. (2007) Reasons for Non- Compliance among Patients Treated under Revised National Tuberculosis Control Program (RNTCP), Tiruvallur District, South India. Indian Journal of Tuberculosis, 54, 130-135.

[7]   Mittal, C. and Gupta, S.C. (2011) Noncompliance to DOTS: How It Can Be Decreased. Indian Journal of Community Medicine, 36, 27-30.

[8]   Dooley, K.E., Lahlou, O., Ghali, I., Knudsen, J., Elmessaoudi, M.D., Cherkaoui, I. and Aouad, R.E. (2011) Risk Factors for Tuberculosis Treatment Failure, Default, or Relapse and Outcomes of Retreatment in Morocco. BMC Public Health, 11, 140-147.

[9]   Sharma, S.K., Kumar, S.K., Saha, P.K., George, N., Arora, S.K., Gupta, D., et al. (2011) Prevalence of Multidrug-Resistant Tuberculosis among Category II Pulmonary Tuberculosis Patients. Indian Journal of Medical Research, 133, 312-315.

[10]   (2014) TB India 2014: Revised National TB Control Program, Annual Status Report. Central TB Division, Directorate General of Health Services, Ministry of Health & Family Welfare, New Delhi, India.

[11]   Government of West Bengal (2013) RNTCP Performance Report for West Bengal 4th Quarter 2013.

[12]   Giuffrida, A. and Torgerson, D.J. (1997) Should We Pay the Patient? Review of Financial Incentives to Enhance Patient Compliance. BMJ, 315, 703-707.

[13]   Buchanan, R.J. (1997) Compliance with Tuberculosis Drug Regimens: Incentives and Enablers Offered by Public Health Departments. American Journal of Public Health, 87, 2014-2017.

[14]   Meichenbaum, D. (1987) TD. Facilitating Treatment Adherence: A Practitioner’s Guidebook. Plenum, New York.

[15]   Pozsik, C.J. (1989) Using Incentives and Enablers in the Tuberculosis Control Program. In: Pozsik, C., Ed., Tuberculosis Control: Enablers and Incentives, American Lung Association of South Carolina, Columbia.

[16]   Volmink, J. and Garner, P. (1997) Systematic Review of Randomised Controlled Trials of Strategies to Promote Adherence to Tuberculosis Treatment. BMJ, 315, 1403-1406.

[17]   Santha, T., Garg, R., Frieden, T.R., Chandrasekaran, V., Subramani, R., Gopi, P.G., et al. (2002) Risk Factors Associated with Default, Failure and Death among Tuberculosis Patients Treated in a DOTS Programme in Tiruvallur District, South India, 2000. International Journal of Tuberculosis and Lung Disease, 6, 780-788.

[18]   Joseph, P., Chandrasekaran, V., Thomas, A., Gopi, P.G., Rajeswari, R., Balasubramanian, R., et al. (2006) Influence of Drug Susceptibility on Treatment Outcome and Susceptibility Profile of “Failures” to Category II Regimen. Indian Journal of Tuberculosis, 53, 141-148.

[19]   Misha, P., Hansen, E.H., Sabroe, S. and Kafle, K.K. (2005) Socio-Economic Status and Adherence to Tuberculosis Treatment: A Case-Control Study in a District of Nepal. International Journal of Tuberculosis and Lung Disease, 9, 1134-1139.