[1] Quigley, H.A. and Broman, A.T. (2006) The Number of People with Glaucoma Worldwide in 2010 and 2020. British Journal of Ophthalmology, 90, 262-267.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1856963/
http://dx.doi.org/10.1136/bjo.2005.081224
[2] Mahalaxmi, D., Samarth, M.M., Shiravadekar, H.S. and Sanghavi, N.M. (1996) Stability-Indicating HPLC Method for Betaxolol HCl and Its Pharmaceutical Dosage Forms. Drug Development and Industrial Pharmacy, 22, 1037-1039.
http://www.tandfonline.com/doi/abs/10.3109/03639049609065938#abstract
http://dx.doi.org/10.3109/03639049609065938
[3] Kaur, I.P. and Kanwar, M. (2002) Ocular Preparations: The Formulation Approach. Drug Development and Industrial Pharmacy, 28, 473-493.
http://www.tandfonline.com/doi/full/10.1081/DDC-120003445#abstract
http://dx.doi.org/10.1081/DDC-120003445
[4] Hamalainen, K.M., Kananen, K., Auriola, S., Kontturi, K. and Urtti, A. (1997) Characterization of Paracellular and Aqueous Penetration Routes in Cornea, Conjunctiva and Sclera. Investigative Ophthalmology and Visual Science, 38, 627-634.
http://www.ncbi.nlm.nih.gov/pubmed/9071216
[5] Keister, J.C., Cooper, E.R., Missel, P.J., Lang, J.C. and Hager, D.F. (1991) Limits on Optimizing Ocular Drug Delivery. Journal of Pharmaceutical Sciences, 80, 50-53.
http://www.ncbi.nlm.nih.gov/pubmed/?term
http://dx.doi.org/10.1002/jps.2600800113
[6] Calvo, C.P., Vila-Jato, J.L. and Alonso, M.J. (1997) Novel Hydrophilic Chitosan-Polyethylene Oxide Nanoparticles as Protein Carriers. Journal of Applied Polymer Science, 63, 125-132.
http://onlinelibrary.wiley.com/doi/10.1002/%28SICI%291097-4628%2819970103%2963:1%3C125::AID-APP13%3E3.0.CO;2-4/abstract
http://dx.doi.org/10.1002/(SICI)1097-4628(19970103)63:1<125::AID-APP13>3.0.CO;2-4
[7] Kaur, I.P. and Smitha, R. (2002) Penetration Enhancers and Ocular Bioadhesives: Two New Avenues for Ophthalmic Drug Delivery. Drug Development and Industrial Pharmacy, 28, 353-369.
http://informahealthcare.com/doi/abs/10.1081/DDC-120002997%20
http://dx.doi.org/10.1081/DDC-120002997
[8] Ludwig, A. (2005) The Use of Mucoadhesive Polymers in Ocular Drug Delivery. Advances Drug Delivery Reviews, 57, 1595-1639.
http://www.ncbi.nlm.nih.gov/pubmed/16198021
http://dx.doi.org/10.1016/j.addr.2005.07.005
[9] Mucha, M. (1997) Rheological Characteristics of Semi-Dilute Chitosan Solutions. Macromolecular Chemistry and Physics, 198, 471-484.
http://onlinelibrary.wiley.com/doi/10.1002/macp.1997.021980220/abstract
http://dx.doi.org/10.1002/macp.1997.021980220
[10] Wang, W. and Xu, D. (1994) Viscosity and Flow Properties of Concentrated Solutions of Chitosan with Different Degrees of Deacetylation. International Journal of Biological Macromolecule, 16, 149-152.
http://www.ncbi.nlm.nih.gov/pubmed/?term
http://dx.doi.org/10.1016/0141-8130(94)90042-6
[11] Alonso, M.J. and Sanchez, A. (2003) The Potential of Chitosan in Ocular Drug Delivery. Journal of Pharmacy and Pharmacology, 55, 1451-1463.
http://onlinelibrary.wiley.com/doi/10.1211/0022357022476/abstract;jsessionid=8714D64E9E7D3894BF48FBA2B0D0912C.f01t04
http://dx.doi.org/10.1211/0022357022476
[12] Bhatta, R.S., Chandasana, H., Chhonker, Y.S., Rathi, C., Kumar, D., Mitra, K. and Shukla, P.K. (2012) Mucoadhesive Nanoparticles for Prolonged Ocular Delivery of Natamycin: In Vitro and Pharmacokinetics Studies. International Journal of Pharmaceutics, 432, 105-112.
http://www.sciencedirect.com/science/article/pii/S0378517312004061
http://dx.doi.org/10.1016/j.ijpharm.2012.04.060
[13] Diebold, A. and Calonge, M. (2010) Applications of Nanoparticles in Ophthalmology. Progress in Retinal and Eye Research, 29, 596-609.
http://www.sciencedirect.com/science?_ob=ArticleListURL&_method=list&_ArticleListID=-782671355&_sort=r&_st=13&view=c&md5=e5bfcd6370882023e9fc1c79a37ae974&searchtype=a
http://dx.doi.org/10.1016/j.preteyeres.2010.08.002
[14] Motwani, S.K., Chopra, S., Talegaonkar, S., Kohli, K., Ahmad, F.J. and Khar, R.K. (2008) Chitosan-Sodium Alginate Nanoparticles as Submicroscopic Reservoirs for Ocular Delivery: Formulation, Optimization and in Vitro Characterization. European Journal of Pharmaceutics and Biopharmaceutics, 68, 513-525.
http://linkinghub.elsevier.com/retrieve/pii/S0939-6411(07)00308-6
[15] Angela, M., Campos, D., Sanchez, A. and Alonso, M.J. (2001) Chitosan Nanoparticles: A New Vehicle for the Improvement of the Delivery of Drugs to the Ocular Surface. Application to Cyclosporin A. International Journal of Pharmaceutics, 224, 159-168.
http://linkinghub.elsevier.com/retrieve/pii/S0378517301007608
http://dx.doi.org/10.1016/S0378-5173(01)00760-8
[16] Ennajih, H., Bouhfid, R., Essassi, E.L.M., Bousmina, M. and El Kadib, A. (2012) Chitosan-Montmorillonite Bio-Based Aerogel Hybrid Microspheres. Microporous and Mesoporous Materials, 152, 208-213.
http://dx.doi.org/10.1002/chem.201104006
[17] Lin, F.H., Lee, Y.H., Jian, C.H., Wong, J.M., Schiech, M.J. and Wang, C.Y. (2002) A Study of Purified Montmorillonite Intercalated with 5-Fluorouracil as Drug Carrier. Biomaterials, 23, 1981-198.
http://www.ncbi.nlm.nih.gov/pubmed/11996039
http://dx.doi.org/10.1016/s0142-9612(01)00325-8
[18] Zheng, J.P., Luan, L., Wang, H.Y., Xi, L.F. and Yao, K.D. (2007) Study on Ibuprofen/Montmorillonite Intercalation Composites as Drug Release System. Applied Clay Science, 36, 297-301.
http://www.sciencedirect.com/science/article/pii/S0169131707000026
http://dx.doi.org/10.1016/j.clay.2007.01.012
[19] Bhatta, R.S., Chandasana, H., Chhonker, Y.S., Rathi, C., Kumar, D., Mitra, K. and Shukla, P.K. (2012) Mucoadhesive Nanoparticles for Prolonged Ocular Delivery of Natamycin: In Vitro and Pharmacokinetics Studies. International Journal of Pharmaceutics, 432, 105-112.
http://www.sciencedirect.com/science/article/pii/S0378517312004061
http://dx.doi.org/10.1016/j.ijpharm.2012.04.060
[20] Qi, L.F., Xu, Z.R., Jiang, X., Hu, C.H. and Zou, X.F. (2004) Preparation and Antibacterial Activity of Chitosan Nanoparticles. Carbohydrate Research, 339, 2693-2700.
http://www.ncbi.nlm.nih.gov/pubmed/15519328
http://dx.doi.org/10.1016/j.carres.2004.09.007
[21] Mahmoud, A.A., El-Feky, G.S., Kamel, R. and Awad, G.E.A. (2011) Chitosan/Sulfobutylether-β-Cyclodextrin Nanoparticles as a Potential Approach for Ocular Drug Delivery. International Journal of Pharmaceutics, 413, 229-236.
http://linkinghub.elsevier.com/retrieve/pii/S0378-5173(11)00358-9
http://dx.doi.org/10.1016/j.ijpharm.2011.04.031
[22] Wilhelmus, K.R. (2001) The Draize Eye Test. Survey of Ophthalmology, 45, 493-515.
http://www.ncbi.nlm.nih.gov/pubmed/11425356
http://dx.doi.org/10.1016/s0039-6257(01)00211-9
[23] Vandenberg, G.W., Drolet, C., Scott, S.L. and Noue, J.D. (2001) Factors Affecting Protein Release from Alginate- Chitosan Coacervate Microcapsules during Production and Gastric/Intestinal Simulation. Journal of Controlled Release, 77, 297-307.
http://www.sciencedirect.com/science/article/pii/S016836590100517X
http://dx.doi.org/10.1016/S0168-3659(01)00517-X
[24] Quan, G. and Tao, W. (2007) Chitosan Nanoparticle as Protein Delivery Carrier—Systematic Examination of Fabrication Conditions for Efficient Loading and Release. Colloid and Surfaces B: Biointerfaces, 59, 24-34.
http://www.sciencedirect.com/science/article/pii/S0927776507001671
[25] Kawashima, Y., Yamamoto, H., Takeuchi, H. and Kuno, Y. (2000) Mucoadhesive DL-Lactide/Glycolide Copolymer Nanoparticles Coated with Chitosan to Improve Oral Delivery of Elcatonin. Pharmaceutical Development and Technology, 5, 77-85.
http://informahealthcare.com/doi/abs/10.1081/PDT-100100522%20
http://dx.doi.org/10.1081/PDT-100100522
[26] Oyarzun-Ampuero, F.A., Brea, J., Loza, M.I., Torres, D. and Alonso, M.J. (2009) Chitosan-Hyaluronic Acid Nanoparticles Loaded with Heparin for the Treatment of Asthma. International Journal of Pharmaceutics, 2, 122-129.
http://www.sciencedirect.com/science/article/pii/S0378517309002129
http://dx.doi.org/10.1016/j.ijpharm.2009.04.009
[27] Schiffelers, R.M., Woodle, M.C. and Scaria, P. (2004) Pharmaceutical Prospects for RNA Interference. Pharmacy Research, 21, 1-7.
http://link.springer.com/article/10.1023%2FB%3APHAM.0000012145.49054.6c