Back
 OJNeph  Vol.5 No.2 , June 2015
Mortality in Kidney Transplantation
Abstract: It’s a retrospective study whose aim was to evaluate the incidence and the mortality in a popula-tion including 329 patients who received first kidney transplants from a living donor in 269 cases and cadaveric donor in 60 cases at Internal Medicine A department between June 1986 and December 2003. Aetiologies of mortality in our kidney transplant recipients were determined. There were 157 males and 75 females having an average age of 30.8 years. After a period of follow-up of 5.64 years, 51 patients (21.98%) died. Aetiologies of mortality were multiple and were known in approximately 98% of cases. Infections were observed in 25 cases. Cancer was observed in 7 cases (13.72%). Patient survival was not affected by gender, donor age or cause of donor death. Infections represent the major cause of mortality in our patients even many years after kidney transplantation. The maximum of death occurred in the 8th year after kidney transplantation.
Cite this paper: Boubaker, K. , Mahfoudhi, M. , Battikh, A. , Kaaroud, H. , Abderrahim, E. , Abdallah, T. and Kheder, A. (2015) Mortality in Kidney Transplantation. Open Journal of Nephrology, 5, 25-28. doi: 10.4236/ojneph.2015.52003.
References

[1]   Sarnak, M.J., Levey, A.S., Schoolwerth, A.C., Coresh, J., Culleton, B., Hamm, L.L., et al. (2003) Kidney Disease as a Risk Factor for Development of Cardiovascular Disease: A Statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention. Circulation, 108, 2154-2169.
http://dx.doi.org/10.1161/01.CIR.0000095676.90936.80

[2]   Hernández, D., Rufinoa, M., González-Posadaa, J.M., Estupinán, S., Pérez, G., Marrero-Miranda, D., et al. (2008) Predicting Delayed Graft Function and Mortality in Kidney Transplantation. Transplantation Reviews, 22, 21-26.
http://dx.doi.org/10.1016/j.trre.2007.09.007

[3]   Wright, L.F. (1991) Survival in Patients with End-Stage Renal Disease. American Journal of Kidney Diseases, 17, 25-28.
http://dx.doi.org/10.1016/S0272-6386(12)80245-9

[4]   Miskulin, D.C., Meyer, K.B., Martin, A.A., Fink, N.E., Coresh, J., Powe, N.R., et al. (2003) Comorbidity and Its Change Predict Survival in Incident Dialysis Patients. American Journal of Kidney Diseases, 41, 149-161.
http://dx.doi.org/10.1053/ajkd.2003.50034

[5]   Gnatta, D., Keitel, E., Heineck, I., Cardoso, B.D., Rodrigues, A.P., Michel, K., et al. (2010) Use of Tacrolimus and the Development of Posttransplant Diabetes Mellitus: A Brazilian Single-Center, Observational Study. Transplantation Proceedings, 42, 475-478.
http://dx.doi.org/10.1016/j.transproceed.2010.02.021

[6]   Blosser, C.D. and Bloom, R.D. (2010) Post Transplant Anemia in Solid Organ Recipients. Transplantation Reviews, 24, 89-98.
http://dx.doi.org/10.1016/j.trre.2010.01.006

[7]   Van Walraven, C., Austin, P.C. and Knoll, G. (2010) Predicting Potential Survival Benefit of Renal Transplantation in Patients with Chronic Kidney Disease. CMAJ, 182, 666-672.
http://dx.doi.org/10.1503/cmaj.091661

[8]   Fuggle, S.V., Allen, J.E., Johnson, R.J., Collett, D., Mason, P.D., Dudley, C., et al. (2010) Factors Affecting Graft and Patient Survival after Live Donor Kidney Transplantation in the UK. Transplantation, 89, 694-701.
http://dx.doi.org/10.1097/TP.0b013e3181c7dc99

[9]   van Leeuwen, M.T., Webster, A.C., McCredie, M.R., Stewart, J.H., McDonald, S.P., Amin, J., et al. (2010) Effect of Reduced Immunosuppression after Kidney Transplant Failure on Risk of Cancer: Population Based Retrospective Cohort Study. BMJ, 340, c570.
http://dx.doi.org/10.1136/bmj.c570

[10]   Shaheen, M.F., Shaheen, F.A., Attar, B., Elamin, K., Al Hayyan, H. and Al Sayyari, A. (2010) Impact of Recipient and Donor Nonimmunologic Factors on the Outcome of Deceased Donor Kidney Transplantation. Transplantation Proceedings, 42, 273-276.
http://dx.doi.org/10.1016/j.transproceed.2009.12.052

[11]   Merion, R.M., Ashby, V.P., Robert, M.A., et al. (2005) Deceased-Donor Characteristics and the Survival Benefit of Kidney Transplantation. JAMA, 294, 2726.
http://dx.doi.org/10.1001/jama.294.21.2726

 
 
Top