IJOC  Vol.1 No.2 , June 2011
A Facile Synthesis of 2-Amino-5-Cyano-4, 6-Disubstitutedpyrimidines under MWI
ABSTRACT
Microwave Assisted Organic Synthesis (MAOS) is energy efficient and effective tool to speed up the synthesis for drug discovery process. In the present study we report a novel protocol for the rapid, high throughput synthesis of mononuclear 2-amino-5-cyano-4,6-disubstituted pyrimidines, adaptable to parallel synthesis for compound libraries. The overall reaction time in hrs has been reduced to 25 - 50 minutes with improved yields.

Cite this paper
nullK. Jain, S. Chaudhari, N. More, K. More, S. Wakedkar and M. Kathiravan, "A Facile Synthesis of 2-Amino-5-Cyano-4, 6-Disubstitutedpyrimidines under MWI," International Journal of Organic Chemistry, Vol. 1 No. 2, 2011, pp. 47-52. doi: 10.4236/ijoc.2011.12009.
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