Health  Vol.7 No.5 , May 2015
Investigation of Affecting Factors on Persistence in the Treatment of Patients under Methadone Maintenance Therapy in Addiction Therapy Centers, Yazd-Iran
Drug addiction is one of the current world’s hygienic, mental and social problems. There are different treatments for this illness. MMT (Methadone Maintenance Therapy) is considered as a standard and acceptable therapy for addiction; and there are many affecting factors regarding gaining success in this type of treatment. In this study, we investigated some of these factors. One of the most important issues in MMT is to keep up patient on his/her treatment till complete abstinence; therefore, it is recommended that the patient does not leave his/her therapy without discretion of the therapist. In this study, 230 patients, who began MMT, and admitted to addiction treatment centers of Yazd province were included. In this study, the survival rate in the first, third, and sixth months were evaluated as 93.9%, 63.48%, and 28.36%, respectively. It was found that following parameters are important in rate of survival during treatment: family support, gender, dose of methadone and concomitant use of morphine during treatment. Moreover, factors like level of education, marital status, age and concomitant use of methamphetamine during treatment can be effective in this regard.

Cite this paper
Vafaeinasab, M. , Farahzadi, M. , Razaghi, O. , Fallahzadeh, R. , Lotfi, M. and Akhondzadeh, S. (2015) Investigation of Affecting Factors on Persistence in the Treatment of Patients under Methadone Maintenance Therapy in Addiction Therapy Centers, Yazd-Iran. Health, 7, 606-616. doi: 10.4236/health.2015.75072.
[1]   Hosseini, F. (2010) Retention Rate in Methadone Maintenance Therapy. Journal of Shaheed Sadoughi University of Medical Sciences, 18, 152-158.

[2]   Ippoliti, D., Davoli, M., Perucci, C.A., Pasqualini, F. and Bargagli, A.M. (1998) Retention in Treatment of Heroin Users in Italy: The Role of Treatment Type and of Methadone Maintenance Dosage. Drug and Alcohol Dependence, 52, 167-171.

[3]   Booth, R.E., Corsi, K.F. and Mikulich-Gillbertson, S.K. (2004) Factors Associated with Methadone Maintenance Treatment Retention among Street-Recruited Injection Drug Users. Drug Alcohol Dependence, 74, 177-185.

[4]   Peles, E., Schreiber, M. and Adelson, M. (2006) Factors Predicting Retention in Treatment: 10-Year Experience of a Methadone Maintenance Treatment (MMT) Clinic. Drug and Alcohol Dependence, 82, 211-217.

[5]   Karimi Talabari, Z. (2013) Reasons of Methadone Maintenance Therapy Drop out in Clients of Iranian National Center for Addiction Studies (INCAS): A Qualitative Study. Iranian Journal of Psychiatry and Clinical Psychology, 18, 299-309.

[6]   John, M., Miichaell, G., Sttewarrt, D., Bestt, D., Farrrrellll, M. and Sttrrang, J. (1998) The Maudsley Addiction Profile: A Brief Instrument for Treatment Outcome Research. National Addiction Centre/Institute of Psychiatry Addiction Sciences Building Windsor Walk London.

[7]   Zuana, J. and Steve, G. (2005) Pharmacology Biochemistry and Behavior. National Institute on Drug Abuse.

[8]   Kaplan, H.I., Freedman, A.M. and Sadock, B.J. (2009) Comprehensive Textbook of Psychiatry. 9th Edition, University of Michigan, Williams &Wilkins, 1380-1432.

[9]   Fakhraie, S.A. and Babayance, A. (2007) Methadone a Good Experience of Maintenance Treatment in Iran. Addiction Journal, 1, 28-31.

[10]   Strang, J. and Tober, G. (2003) Methadone Matters: Evolving Community Methadone Treatment of Opiate Addition Book. Informa Health Care, United Kingdom, 254.

[11]   Miguel, D. (1997) Predictors of Patient Retention in a Newly Established Methadon Maintenance Treatment Programe. Addiction, 92, 1353-1360.

[12]   Langendam, M.W., Van Brussel, G.H., Coutinho, R.A. and Van Ameijden, E.J. (2000) Methadone Maintenace and Cessation of Injecting Drug Use: Results from the Amesterdam-Cohort Study. Addiction, 45, 591-600.

[13]   Lejuez, C.W., Zvolensky, M.J., Daughters, S.B., Bornovalova, M.A., Paulson, A. and Tull, M.T. (2008) Anxiety Sensitivity: A Unique Predictor of Dropout among Inner-City Heroin and Crack/Cocaine Users in Residential Substance Use Treatment. Behaviour Research and Therapy, 46, 811-818.

[14]   Ward, J., Hall, W. and Mattick, R.P. (1999) Role of Maintenance Treatment in Opioid Dependence. Lancet, 353, 221-226.

[15]   McKellar, J., Kelly, J., Harris, A. and Moos, R. (2006) Pretreatment and during Treatment Risk Factors for Dropout among Patients with Substance Use Disorders. Addictive Behaviors, 31, 450-460.