Clinical infection with varicella in both its’ forms, primary and reactivation, can be associated with a variety of complications. Cardiac complications, though very rare, have been associated with the primary form of varicella zoster and as such should be recognized in order to initiate early treatment and prevent morbidity and mortality. However, cardiac complications have not been described in association with the reactivation form of varicella. We report a case of an adult immunocompetent male who presented with herpes zoster complicated by pericarditis with pericardial effusion and a positive varicella zoster virus (VZV) polymerase chain reaction (PCR) in pericardial fluid.
Cite this paper
Nasreddine, R. , Mollaei, C. , Bahous, J. , Azar, E. and Afif, C. (2015) Shingles and Pericarditis: A Rare Combination. International Journal of Clinical Medicine
, 322-325. doi: 10.4236/ijcm.2015.65041
 Cohen, J.I. (2013) Herpes Zoster. The New England Journal of Medicine, 369, 255-263. http://dx.doi.org/10.1056/NEJMcp1302674
 Fashner, J. and Bell, A.L. (2011) Herpes Zoster and Postherpetic Neuralgia: Prevention and Management. American Family Physician, 83, 1432-1437.
 Hackel, D.B. (1953) Myocarditis in Association with Varicella. The American Journal of Pathology, 29, 369-379.
 Sampson, C.C. (1959) Varicella Myocarditis. Journal of the National Medical Association, 51, 138-139.
 Winfield, C.R. and Joseph, S.P. (1980) Herpes Zoster Pericarditis. British Heart Journal, 43, 597-599. http://dx.doi.org/10.1136/hrt.43.5.597
 Seddon, D.J. (1986) Pericarditis with Pericardial Effusion Complicating Chickenpox. Postgraduate Medical Journal, 62, 1133-1134. http://dx.doi.org/10.1136/pgmj.62.734.1133
 Abrams, D., Derrick, G., Penny, D.J., Shinebourne, E.A. and Redington, A.N. (2001) Cardiac Complications in Children Following Infection with Varicella Zoster Virus. Cardiology in the Young, 11, 647-652. http://dx.doi.org/10.1017/S1047951101001019
 Nandeesh, B.N., Mahadevan, A., Yasha, T.C. and Shankar, S.K. (2009) Hemorrhagic Pericarditis in a Child with Primary Varicella Infection (Chickenpox). Indian Journal of Pathology & Microbiology, 52, 237-239. http://dx.doi.org/10.4103/0377-4929.48930
 Kao, K.L., Yeh, S.J. and Chen, C.C. (2010) Myopericarditis Associated with Varicella Zoster Virus Infection. Pediatric Cardiology, 31, 703-706. http://dx.doi.org/10.1007/s00246-009-9637-5
 Sayin, M.R., Karabag, T., Celik, O., Cetiner, M.A., Cil, C. and Aydin, M. (2011) Varicella Zoster Myopericarditis. Journal of Medical Cases, 2, 287-288. http://dx.doi.org/10.4021/jmc398w
 De, A., Myridakis, D., Kerrigan, M. and Kiblawi, F. (2011) Varicella Myopericarditis Mimicking Myocardial Infarction in a 17-Year-Old Boy. Texas Heart Institute Journal, 38, 288-290.
 Mohsen, A.H. and McKendrick, M. (2003) Varicella Pneumonia in Adults. European Respiratory Journal, 21, 886-891. http://dx.doi.org/10.1183/09031936.03.00103202
 Gnann, J.W. (2002) Varicella-Zoster Virus: Atypical Presentations and Unusual Complications. The Journal of Infectious Diseases, 186, S91-S98. http://dx.doi.org/10.1086/342963