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 OJU  Vol.5 No.4 , April 2015
Can Bladder Irrigation Reduce the Morbidity of Bladder Stone in Patients with Spinal Cord Injury?
Abstract: Objective: To assess the safety and efficacy of bladder irrigation for reducing the morbidity of bladder stones in patients with neurological lower urinary tract dysfunction (NLUTD). Methods: From June 2012 to July 2013, patients with NLUTD were prospectively randomized and assigned to either a bladder irrigation group or a no bladder irrigation group. Bladder irrigations were performed twice a week by urologists. Patients were followed up at 6 months respectively. Primary outcomes were Incontinence-Specific Quality-of-Life Instrument (I-QoL), the rate incidences of bladder stone. All adverse events were also noted. Results: A total of 80 eligible patients participated and 78 (97.5%) patients (bladder irrigation, n = 39; no bladder irrigation, n = 39) completed 24 weeks of follow-up. Out of the 78 patients, 19 (24.3%) developed bladder stones. All occurred in no bladder irrigation group. In 8 of the 19 patients (42.1%), stones were only detected by cystoscopy. The bladder stones were mostly thin with an eggshell appearance (78.95% for diameter of stone < 5 mm, 84.21% for volume of bladder stone < 0.2 cm3). Bladder stones were removed by vigorous bladder irrigation guided by ultrasound (73.68%) or endoscopic lithotripsy (26.32%). The I-QOL was significantly better in the bladder irrigation group than in no bladder irrigation group at weeks 6, 12, 18, and 24 of follow-up. Conclusion: Bladder irrigation may be more effective and safer than no bladder irrigation for reducing the morbidity of bladder stone in spinal cord injury patients.
Cite this paper: Chen, H. , Xie, K. , Jiang, C. , Yang, X. , Zeng, J. , Huang, M. , Liu, Q. , Huang, J. , Huang, T. , Li, Y. , Liu, J. and Xie, S. (2015) Can Bladder Irrigation Reduce the Morbidity of Bladder Stone in Patients with Spinal Cord Injury?. Open Journal of Urology, 5, 42-47. doi: 10.4236/oju.2015.54007.
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