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 AJPS  Vol.6 No.7 , April 2015
Hepatoprotective Activity of Plant Peptides
O. G. Kulikova1, D. I. Maltsev1, A. P. Ilyina1, V. P. Yamskova2, I. A. Yamskov1
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Abstract: Peptides (molecular weights are 1200 – 11,600 Da) biologically acting at concentration 10-8 - 10-15 mg/ml were obtained from leaves of dill Anethum graveolens L. and celandine Chelidonium majus L. by circular dichroism (CD) spectroscopy. We have shown that these peptides form second structure characterized by the prevalence of β-structures and coil in water solution. In model of organotypic roller culturing of triton liver in vitro, the ability of the peptides isolated from Anethum graveolens L. and Chelidonium majus L. at concentration 10-8 - 10-15 mg/ml to influence increasing of pigment cells, which provided protective function of organism, was demonstrated.
Keywords: Peptides, Medical Plants, Organotypic Roller Culturing, Newt Liver
Cite this paper: Kulikova, O. , Maltsev, D. , Ilyina, A. , Yamskova, V. and Yamskov, I. (2015) Hepatoprotective Activity of Plant Peptides. American Journal of Plant Sciences, 6, 848-855. doi: 10.4236/ajps.2015.67092.
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