Background: Intracystic papillary breast cancer is a very rare tumor that occurs most frequently in elderly postmenopausal women. Aim: In this article we presented a case of a 66-year-old woman who underwent excisional biopsy due to a right breast mass. Case presentation: Histological examination revealed the “pure” encapsulated papillary breast carcinoma without coexisting in situ neoplasm and/or invasive carcinoma. This is a rare lesion of the breast that can clinically mimic breast benign mass with only local or regionally aggressive course. Conclusion: In order to avoid misdiagnosis, both the clinician and the breast radiologist should have the possibility of diagnosing this tumor. Intracystic papillary carcinoma of the breast associated with lymph node metastasis has rarely been reported, but the sentinel lymph node biopsy may be prudent in such cases, despite the non aggressive behavior.
 Rakha, E.A., Gandhi, N., Climent, F., van Deurzen, C.H., Haider, S.A., Dunk, L., Lee, A.H., Macmillan, D. and Ellis, I.O. (2011) Encapsulated Papillary Carcinoma of the Breast: An Invasive Tumor with Excellent Prognosis. American Journal of Surgical Pathology, 35, 1093-1103.
 Mulligan, A.M. and O’Malley, F.P. (2007) Metastatic Potential of Encapsulated (Intracystic) Papillary Carcinoma of the Breast: A Report of 2 Cases with Axillary Lymph Node Micrometastases. International Journal of Surgical Pathology, 15, 143-147.
 Rodríguez, M.C., Secades, A.L. and Angulo, J.M. (2010) Best Cases from the AFIP: Intracystic Papillary Carcinoma of the Breast. Radiographics, 30, 2021-2027.
 Dogan, B.E., Whitman, G.J., Middleton, L.P. and Phelps, M. (2003) Intracystic Papillary Carcinoma of the Breast. American Journal of Roentgenology, 181, 186.
 Akagi, T., Kinoshita, T., Shien, T., Hojo, T., Akashi-Tanaka, S. and Murata, Y. (2009) Clinical and Pathological Features of Intracystic Papillary Carcinoma of the Breast. Surgery Today, 39, 5-8.
 Grabowski, J., Salzstein, S.L., Sadler, G.R. and Blair, S. (2008) Intracystic Papillary Carcinoma: A Review of 917 Cases. Cancer, 113, 916-920.
 Liu, Z.Y., Liu, N., Wang, Y.H., Yang, C.C., Zhang, J., Ly, S.H. and Niu, Y. (2013) Clinicopathologic Characteristics and Molecular Subtypes of Invasive Papillary Carcinoma of the Breast: A Large Case Study. Journal of Cancer Research and Clinical Oncology, 139, 77-84.
 Solorzano, C.C., Middleton, L.P., Hunt, K.K., Mirza, N., Meric, F., Kuerer, H.M., Ross, M.I., Ames, F.C., Feig, B.W., Pollock, R.E., Singletary, S.E. and Babiera, G. (2002) Treatment and Outcome of Patients with Intracystic Papillary Carcinoma of the Breast. The American Journal of Surgery, 184, 364-368.