Back
 FNS  Vol.6 No.4 , March 2015
Measures of Nutritional Status and Quality of Life in Adult People Living with HIV/AIDS at a Tertiary Hospital in Nigeria
Abstract: Background & Aims: The study investigated the relationship between objective and subjective nutritional status parameters and quality of life in HIV seropositive patients. Methods: Retrospective review of clinic records of 150 HIV seropositive patients at a teaching hospital in Nigeria. Nutritional status was evaluated objectively with anthropometry including body mass index (BMI), subjectively with malnutrition universal screening tool (MUST) and subjective global assessment (SGA) tool. Data on quality of life (QOL) assessed with WHOQOL (Bref), and CD4 count were extracted. Correlation analysis and linear regression were done to investigate the relationship between variables, level of significance set at p < 0.05. Results: Only BMI has weak positive correlation with the psychological domain (r = 0.231, p < 0.05). MUST and SGA have significant negative correlations with most of the quality of life domains. MUST correlated with the following domains: physical; (r = -0.207), psychological; (r = -0.193) and environmental; (r = -0.132). While SGA correlated with the physical domain; (r = -0.2470) and psychological domain; (r = -0.337), p < 0.05 respectively. The CD4 count correlated with percentage body fat (r = 0.224), MUST (r = -0.186) and SGA (r = -0.192), p < 0.05 respectively, but not with any of the QOL domains. Weight, MUST, SGA, percentage body fat were significant predictors of the percentage weight change in 6 months. Conclusions: BMI has significant positive association with psychological domain of QOL. MUST and SGA have significant negative association with certain domains. QOL did not predict short-term weight changes, as did the current weight, MUST, and SGA.
Cite this paper: Folasire, O. , Folasire, A. and Sanusi, R. (2015) Measures of Nutritional Status and Quality of Life in Adult People Living with HIV/AIDS at a Tertiary Hospital in Nigeria. Food and Nutrition Sciences, 6, 412-420. doi: 10.4236/fns.2015.64042.
References

[1]   Uthman, O.A. (2008) Prevalence and Pattern of HIV-Related Malnutrition among Women in Sub-Saharan Africa: A Meta-Analysis of Demographic Health Surveys. BMC Public Health, 8, 226.
http://www.biomedcentral.com/1471-2458/8/226

[2]   Koethe, J.R., Chi, B.H., Megazzini, K.M., Heimburger, D.C. and Stringer, J.S.A. (2011) Macronutrient Supplementation for Malnourished HIV-Infected Adults: A Review of the Evidence in Resource-Adequate and Resource-Constrained Settings. Clinical Infectious Disease, 49, 787-798.
http://dx.doi.org/10.1086/605285

[3]   Nerad, J., Romeyn, M., Silverman, E., Allen-reid, J., Dieterich, D., Merchant, J., et al. (2003) General Nutrition Management in Patients Infected with Human Immunodeficiency Virus. Clinical Infectious Disease, 36, S52-S62.
http://dx.doi.org/10.1086/367559

[4]   British Association of Parenteral and Enteral Nutrition (BAPEN) (2003) The “MUST” Explanatory Booklet: A Guide to the “Malnutrition Universal Screening Tool” (“MUST”) for Adults. British Association for Parental and Enteral Nutrition, Redditch.

[5]   Skevington, S.M., Lotfy, M. and Connell, K.A.O. (2004) The World Health Organization’s WHOQOL-BREF Quality of Life Assessment: Psychometric Properties and Results of the International Field Trial a Report from the WHOQOL Group, 299-310.

[6]   Saxena, S., Carlson, D. and Billington, R. (2001) WHOQOL Group: The WHO Quality of Life Assessment Instrument ( WHOQOL-Bref ): The Importance of Its Items for Cross-Cultural Research. Quality of Life Research, 10, 1171592.
http://dx.doi.org/10.1023/A:1013867826835

[7]   Bhowmik, A., Ghugre, P., Udipi, S. and Guha, S.K. (2012) Nutritional Status and Quality of Life of Women with HIV/ AIDS. American Journal of Infectious Disease, 8, 13-8.
http://dx.doi.org/10.3844/ajidsp.2012.13.18

[8]   Hsiung, P., Fang, C., Chang, Y., Chen, M. and Wang, J. (2005) Comparison of WHOQOL-BREF and SF-36 in Patients with HIV Infection. Quality of Life Research, 14, 141-150.
http://dx.doi.org/10.1007/s11136-004-6252-z

[9]   Bello, S.I. and Bello, I.K. (2013) Quality of Life of HIV/AIDS Patients in a Secondary Health Care Facility, Ilorin, Nigeria. Baylor Universit Medical Center Proceedings, 116-119.

[10]   Hu, W., Jiang, H., Chen, W., He, S., Deng, B., Wang, W., et al. (2011) Malnutrition in Hospitalized People Living with HIV/AIDS: Evidence from a Cross-Sectional Study from Chengdu, China. Asia Pacific Journal of Clinical Nutrition, 20, 544-550.

[11]   Suttajit, M. (2007) Advances in Nutrition Support for Quality of Life in HIV/AIDS. Asia Pacific Journal of Clinical Nutrition, 16, S318-S322.

[12]   Burgin, J., Nicholas, S. and Dalrymple, N. (2008) The Nutritional Status of Clinic Attendees Living with HIV/AIDS in St Vincent and the Grenadines. West Indian Medical Journal, 57, 438-443.

[13]   Venter, E., Gericke, G.J. and Bekker, P.J. ( 2009) Nutritional Status, Quality of Life and CD4 Cell Count of Adults Living with HIV/AIDS in the Ga-Rankuwa Area (South Africa). South African Journal of Clinical Nutrition, 22, 124129.

[14]   Giri, S., Neupane, M., Pant, S., Timalsina, U., Koirala, A.S. and Sharma, S. (2013) Quality of Life among People Living with Acquired Immune Deficiency Syndrome Receiving Anti-Retroviral Therapy: A Study from Nepal. HIV/AIDSResearch Palliative CARE, 3, 277-282.

[15]   dos Santos, C.E., Fraca Jr., J.I. and Lopes, F. (2007) Quality of Life of People Living with HIV/AIDS in Sao Paulo, Brazil. Review Saude Publication, 41, S1-S7.

[16]   Nirmal, B., Divya, K.R., Dorairaj, V.S. and Venkateswaran, K. (2008) Quality of Life in HIV/AIDS Patients: A Cross-Sectional Study in South India. Indian Journal of Sexual Transmitted Disease, 29, 15-17.
http://dx.doi.org/10.4103/0253-7184.42708

[17]   Kumar, A., Girish, H., Nawaz, A., Balu, P. and Kumar, B. (2014) Determinants of Quality of Life among People Living with HIV/AIDS: A Cross Sectional Study in Central Karnataka, India. International Journal of Medical Science Publication, 3, 1413-1417.
http://www.scopemed.org/?mno=165368

[18]   Isenring, E.A., Capra, S. and Bauer, J.D. (2004) Nutrition Intervention Is Beneficial in Oncology Outpatients Receiving Radiotherapy to the Gastrointestinal or Head and Neck Area. British Journal of Cancer, 91, 447-452.
http://www.pubmedcentral.nih.gov/ http://dx.doi.org/10.1038/sj.bjc.6601962

[19]   Isenring, E.A., Bauer, J. and Capra, S. (2003) The Scored Patient-Generated Subjective Global Assessment (PG-SGA) and Its Association with Quality of Life in Ambulatory Patients Receiving Radiotherapy. European Journal of Clinical Nutrition, 57, 305-309.
http://dx.doi.org/10.1038/sj.ejcn.1601552

[20]   Lis, C.G., Gupta, D., Lammersfeld, C.A., Markman, M. and Vashi, P.G. (2012) Role of Nutritional Status in Predicting Quality of Life Outcomes in Cancer—A Systematic Review of the Epidemiological Literature. Nutrition Journal, 11, 2-18.
http://dx.doi.org/10.1186/1475-2891-11-27

[21]   Makhija, S. and Baker, J. (2008) The Subjective Global Assessment: A Review of Its Use in Clinical Practice. Nutrition in Clinical Practice, 23, 405-409.
http://dx.doi.org/10.1177/0884533608321214

[22]   Tapiawala, S., Vora, H., Patel, Z., Badve, S. and Shah, B. (2006) Subjective Global Assessment of Nutritional Status of Patients with Chronic Renal Insufficiency and End Stage Renal Disease on Dialysis. Journal of the Association of Physicians of India, 54, 923-926.

[23]   Deurenberg, P., Weststrate, J.A. and Seidell, J.C. (1991) Body Mass Index as a Measure of Body Fatness: Ageand Sex-Specific Prediction Formulas. British Journal of Nutrition, 65, 105-114.
http://dx.doi.org/10.1079/BJN19910073

[24]   Folasire, O.F., Irabor, A.E. and Folasire, A.M. (2012) Quality of Life of People Living with HIV and AIDS Attending the Antiretroviral Clinic, University College Hospital, Nigeria. African Journal of Primary Health Care & Family Medicine, 4, 1-8.
http://www.phcfm.org/index.php/phcfm/article/view/294

[25]   World Health Organisation (1997) WHOQOL-BREF Scoring Guide.

[26]   Pallant, J. (2005) SPSS Survival Manual. 2nd Edition, Open University Press, Berkshire.

[27]   Anand, D., Puri, S. and Mathew, M. (2012) Assessment of Quality of Life of HIV-Positive People Receiving ART: An Indian Perspective. Indian Journal of Community Medicine, 37, 165-169.
http://dx.doi.org/10.4103/0970-0218.99918

[28]   Friedland, J., Renwick, R. and McColl, M. (1996) Coping and Social Support as Determinants of Quality of Life in HIV/AIDS. AIDS Care, 8, 15-31.
http://dx.doi.org/10.1080/09540129650125966

[29]   Linares Guerra, E.M., Santana, P.S., Carrilo, F.O., Leon Sanchez, M.A., Sanabria Negrin, J.G., Acosta Nunez, N., et al. (2013) Nutritional Status of the Persons Living with HIV/AIDS, Its Relationship with T CD4 + Cells Count. Nutrition Hospitalia, 28, 2197-2207.

 
 
Top