Mycosis fungoides (MF) is the most common cutaneous T-cell lymphoma accounting for approximately half of all cutaneous T-cell lymphomas. Radiation therapy is an effective treatment for early stage MF and has been shown to result in long-term disease-free intervals, with even curative potential. Radiation is also effective as palliative treatment for the localized lesion resistant to the topic or other treatments. In the current study, we report using high dose rate (HDR) radiation treatment for a patient with resistant mycosis fungoides involving the wrist. We report a convenient treatment with an ideal radiation dose distribution, and a excellent clinical outcome.
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Shukla, G. , Lockamy, V. , Keller, J. , Sahu, J. , Pro, B. , Alpdogan, O. and Shi, W. (2015) High Dose Rate (HDR) Brachytherapy for Mycosis Fungoides of the Wrist. International Journal of Clinical Medicine
, 154-157. doi: 10.4236/ijcm.2015.63020
 Bradford, P.T., Devesa, S.S., Anderson, W.F. and Toro, J.R. (2009) Cutaneous Lymphoma Incidence Patterns in the United States: A Population-Based Study of 3884 Cases. Blood, 113, 5064-5073. http://dx.doi.org/10.1182/blood-2008-10-184168
 Jones, G.W., Hoppe, R.T. and Glatstein, E. (1995) Electron Beam Treatment for Cutaneous T-Cell Lymphoma. Hematology/Oncology Clinics of North America, 9, 1057-1076.
 Kim, Y.H., Jensen, R.A., Watanabe, G.L., Varghese, A. and Hoppe, R.T. (1996) Clinical Stage IA (Limited Patch and Plaque) Mycosis Fungoides. A Long-Term Outcome Analysis. Archives of Dermatology, 132, 1309-1313.http://dx.doi.org/10.1001/archderm.1996.03890350051009
 Vijande, J., Ballester, F., Ouhib, Z., Granero, D., Pujades-Claumarchirant, M.C. and Perez-Calatayud, J. (2012) Dosimetry Comparison between TG-43 and Monte Carlo Calculations Using the Freiburg Flap for Skin High-Dose-Rate Brachytherapy. Brachytherapy, 11, 528-535. http://dx.doi.org/10.1016/j.brachy.2011.11.005
 Cotter, G.W., Baglan, R.J., Wasserman, T.H. and Mill, W. (1983) Palliative Radiation Treatment of Cutaneous Mycosis Fungoides—A Dose Response. International Journal of Radiation Oncology*Biology* Physics, 9, 1477-1480.http://dx.doi.org/10.1016/0360-3016(83)90321-8
 Neelis, K.J., Schimmel, E.C., Vermeer, M.H., Senff, N.J., Willemze, R. and Noordijk, E.M. (2009) Low-Dose Palliative Radiotherapy for Cutaneous B- and T-Cell Lymphomas. International Journal of Radiation Oncology*Biology* Physics, 74, 154-158. http://dx.doi.org/10.1016/j.ijrobp.2008.06.1918
 Thomas, T.O., Agrawal, P., Guitart, J., et al. (2013) Outcome of Patients Treated with a Single-Fraction Dose of Palliative Radiation for Cutaneous T-Cell Lymphoma. International Journal of Radiation Oncology*Biology* Physics, 85, 747-753. http://dx.doi.org/10.1016/j.ijrobp.2012.05.034