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 FNS  Vol.6 No.3 , March 2015
Underweight and Obesity in Low Birth Weight Children in Early Infancy in Japan
Rena Kato1, Masaru Kubota1, Hiromi Saito1, Yukihiro Takahashi2
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Abstract: Introduction: Although there are several reports on the prevalence of underweight or obesity in low birth weight (LBW, <2.5 kg) children, there are few longitudinal studies from birth to early infancy. Methods: We enrolled 177 (93 boys) LBW and 2485 (1267 boys) normal birth weight (NBW, ≥2.5 and <4.0 kg) children. Height and weight data at birth and at 1.5, 3.5, and 5 years were obtained from mother-health child records. Underweight and obesity were defined as <5th percentile and ≥90th percentile of the body mass index (BMI), respectively, based on reference values for Japanese children. Results: LBW children had accelerated growth from birth to age 3.5 years, but at Age 5, both sexes had significantly lesser height and weight z-scores, with notably lesser BMI percentile scores for girls, compared with NBW children. The prevalence of underweight was significantly higher in the LBW children throughout the study period. There were no significant differences in the prevalence of obesity between the two groups, except for at birth. Multiple regression analysis revealed that small-for-gestational age was associated with underweight at Age 5 years. Conclusions: This study indicates that, up to Age 5, underweight is a more serious problem than obesity in LBW children. Our results suggest that careful observation of growth from early infancy is necessary to prevent the occurrence of underweight in early infancy.
Keywords: Growth, Low Birth Weight, Obesity, Small-for-Gestational Age, Underweight
Cite this paper: Kato, R. , Kubota, M. , Saito, H. and Takahashi, Y. (2015) Underweight and Obesity in Low Birth Weight Children in Early Infancy in Japan. Food and Nutrition Sciences, 6, 339-347. doi: 10.4236/fns.2015.63034.
References

[1]   Horbar, J.D., Badger, G.J., Carpenter, J.H., Fanaroff, A.A., Kilpatrick, S., LaCorte, M., et al. (2002) Trends in Mortality and Morbidity for Very Low Birth Weight Infants, 1991-1999. Pediatrics, 110, 143-151.
http://dx.doi.org/10.1542/peds.110.1.143

[2]   Kusuda, S., Fujimura, M., Uchiyama, A., Totsu, S. and Matsunami, K. (2012) Trends in Morbidity and Mortality among Very-Low-Birth-Weight Infants from 2003 to 2008 in Japan. Pediatric Research, 72, 531-538.
http://dx.doi.org/10.1038/pr.2012.114

[3]   Saigal, S. and Doyle, L.W. (2008) An Overview of Mortality and Sequelae of Preterm Birth from Infancy to Adulthood. Lancet, 371, 261-269. http://dx.doi.org/10.1016/S0140-6736(08)60136-1

[4]   United Nations Children’s Fund (UNICEF) (2013) Child Well-Being in Rich Countries: A Comparative Overview.
Children%E2%80%99s+Fund+%28UNICEF%29.+Child+wellbeing+in+rich+countries'>http://www.unicef-irc.org/publications/pdf/rc11_eng.pdf#search='United+Nations+
Children%E2%80%99s+Fund+%28UNICEF%29.+Child+wellbeing+in+rich+countries

[5]   Yoshida, H., Kato, N. and Yokoyama, T. (2014) Current Trends in Low Birth Weight Infants in Japan. Journal of the National Institute of Public Health, 63, 2-16. (In Japanese)

[6]   Monset-Couchard, M. and de Bethmann, O. (2000) Catch-Up Growth in 166 Small-for-Gestational Age Premature Infants Weighing Less than 1000 g at Birth. Biology of the Neonate, 78, 161-167.
http://dx.doi.org/10.1159/000014265

[7]   Itabashi, K., Mishina, J., Tada, H., Sakurai, M., Nanri, Y. and Hirohata, Y. (2007) Longitudinal Follow-Up of Height up to Five Years of Age in Infants Born Preterm Small for Gestational Age; Comparison to Full-Term Small for Gestational Age Infants. Early Human Development, 83, 327-333.
http://dx.doi.org/10.1016/j.earlhumdev.2006.07.002

[8]   Trebar, B., Traunecker, R., Selbmann, H.K. and Ranke, M.B. (2007) Growth during the First Two Years Predicts PreSchool Height in Children Born with Very Low Birth Weight (VLBW): Results of a Study of 1320 Children in Germany. Pediatric Research, 62, 209-214.
http://dx.doi.org/10.1203/PDR.0b013e3180ca7c5b

[9]   Doyle, L.W., Faber, B., Callanan, C., Ford, G.W. and Davis, N.M. (2004) Extremely Low Birth Weight and Body Size in Early Adulthood. Archives of Disease in Childhood, 89, 347-350.
http://dx.doi.org/10.1136/adc.2002.025924

[10]   Roberts, G., Cheong, J., Opie, G., Carse, E., Davis, N., Duff, J., et al. (2013) Growth of Extremely Preterm Survivors from Birth to 18 Years of Age Compared with Term Controls. Pediatrics, 131, 439-445.
http://dx.doi.org/10.1542/peds.2012-1135

[11]   Casey, P.H. (2008) Growth of Low Birth Weight Preterm Children. Seminars in Perinatology, 32, 20-27.
http://dx.doi.org/10.1053/j.semperi.2007.12.004

[12]   Kelishadi, R. and Poursafa, P. (2014) A Review on the Genetic, Environmental, and Lifestyle Aspects of the Early-Life Origins of Cardiovascular Disease. Current Problems in Pediatric and Adolescent Health Care, 44, 54-72.
http://dx.doi.org/10.1016/j.cppeds.2013.12.005

[13]   Barker, D.J.P., Winter, P.D., Osmond, C., Margetts, B. and Simmonds, S.J. (1989) Weight in Infancy and Death from Ischaemic Heart Disease. The Lancet, 2, 577-580.
http://dx.doi.org/10.1016/S0140-6736(89)90710-1

[14]   Euser, A.M., Finken, M.J.J., Keijzer-Veen, M.G., Hille, E.T., Wit, J.M. and Dekker, F.W. (2005) Associations between Prenatal and Infancy Weight Gain and BMI, Fat Mass, and Fat Distribution in Young Adulthood: A Prospective Cohort Study in Males and Females Born Very Preterm. The American Journal of Clinical Nutrition, 81, 480-487.

[15]   Huxley, R.R., Shiell, A.W. and Law, C.M. (2000) The Role of Size at Birth and Postnatal Catch-Up Growth in Determining Systolic Blood Pressure: A Systematic Review of the Literature. Journal of Hypertension, 18, 815-831.
http://dx.doi.org/10.1097/00004872-200018070-00002

[16]   Regan, F.M., Cutfield, W.S., Jefferies, C., Robinson, E. and Hofman, P.L. (2006) The Impact of Early Nutrition in Premature Infants on Later Childhood Insulin Sensitivity and Growth. Pediatrics, 118, 1943-1949.
http://dx.doi.org/10.1542/peds.2006-0733

[17]   Nobili, V., Alisi, A., Panera, N. and Agostoni, C. (2008) Low Birth Weight and Catch-up-Growth Associated with Metabolic Syndrome: A Ten Year Systematic Review. Pediatric Endocrinology Reviews, 6, 241-247.

[18]   Eriksson, J.G., Forsén, T., Tuomilehto, J., Osmond, C. and Barker, D.J.P. (2001) Early Growth and Coronary Heart Disease in Later Life: Longitudinal Study. BMJ, 322, 949-953.
http://dx.doi.org/10.1136/bmj.322.7292.949

[19]   Barker, D.J.P. and Osmond, C. (1986) Infant Mortality, Childhood Nutrition, and Ischaemic Heart Disease in England and Wales. The Lancet, 1, 1077-1081.
http://dx.doi.org/10.1016/S0140-6736(86)91340-1

[20]   Gluckman, P.D. and Hanson, H.A. (2004) Living with the Past: Evolution, Development, and the Patterns of Disease. Science, 305, 1733-1736.
http://dx.doi.org/10.1126/science.1095292

[21]   Kato, R., Kubota, M., Higashiyama, Y. and Nagai, A. (2014) Longitudinal Study of Thinness from Birth to Early Childhood: The Association with Parental Thinness. Acta Paediatrica, 103, 1285-1289.
http://dx.doi.org/10.1111/apa.12810

[22]   Kato, N. (2009) Construction of BMI for Age References for Japanese Children from the 2000 National Growth Survey. Journal of Japanese Association for Human Auxology, 15, 37-44.

[23]   Must, A., Dallal, G.E. and Dietz, W.H. (1991) Reference Data for Obesity: 85th and 95th Percentiles of Body Mass Index (wt/ht2) and Triceps Skinfold Thickness. The American Journal of Clinical Nutrition, 53, 839-846.

[24]   Wang, Y., Monteiro, C. and Popkin, B.M. (2002) Trends of Obesity and Underweight in Older Children and Adolescents in the United States, Brazil, China, and Russia. The American Journal of Clinical Nutrition, 75, 971-977.

[25]   Mak, K.K. and Tan, S.H. (2012) Underweight Problems in Asian Children and Adolescents. European Journal of Pediatrics, 171, 779-785.
http://dx.doi.org/10.1007/s00431-012-1685-9

[26]   Cole, T.J., Bellizzi, M.C., Flegal, K.M. and Dietz, W.H. (2000) Establishing a Standard Definition for Child Overweight and Obesity Worldwide: International Survey. BMJ, 320, 1240-1245.
http://dx.doi.org/10.1136/bmj.320.7244.1240

[27]   Matsuzawa, Y., Inoue, S., Ikeda, Y., Sakata, T., Saito, Y., Sato, Y., et al. (2000) A New Criteria of Judgment of Obesity and Diagnosis of Pathological Obesity. Journal of Japan Society for the Study of Obesity, 6, 18-28. (In Japanese)

[28]   Hack, M., Shuluchter, M., Cartar, L., Rahman, M., Cuttler, L. and Borawski, E. (2003) Growth of Very Low Birth Weight Infants to Age 20 Years. Pediatrics, 112, 30-38.
http://dx.doi.org/10.1542/peds.112.1.e30

[29]   Bracewell, M.A., Hennessy, E.M., Wolke, D. and Marlow, N. (2008) The EPI Cure Study: Growth and Blood Pressure at 6 Years of Age Following Extremely Preterm Birth. Archives of Disease in Childhood Fetal and Neonatal Edition, 93, 108-114.
http://dx.doi.org/10.1136/adc.2007.118596

[30]   Euser, A.M., Wit, C.C., Finken, M.J.J., Rijken, M. and Wit, J.M. (2008) Growth of Preterm Born Children. Hormone Research, 70, 319-328.
http://dx.doi.org/10.1159/000161862

[31]   Saigal, S., Stoskopf, B., Streiner, D., Paneth, N., Pinelli, J. and Boyle, M. (2006) Growth Trajectories of Extremely Low Birth Weight Infants from Birth to Young Adulthood: A Longitudinal, Population-Based Study. Pediatric Research, 60, 751-758.
http://dx.doi.org/10.1203/01.pdr.0000246201.93662.8e

[32]   Yang, X.L., Ye, R.W., Zheng, J.C., Jin, L., Liu, J.M. and Ren, A.G. (2010) Analysis on Influencing Factors for Stunting and Underweight among Children Aged 3-6 Years in 15 Counties of Jiangsu and Zhejiang Provinces. Chinese Journal of Epidemiology, 31, 506-509. (In Chinese)

[33]   Hack, M., Schluchter, M., Margevicius, S., Andreias, L., Taylor, G. and Cuttler, L. (2014) Trajectory and Correlates of Growth of Extremely Low Birth Weight Adolescents. Pediatric Research, 75, 358-366.
http://dx.doi.org/10.1038/pr.2013.209

[34]   Christian, P., Lee, S.E., Angel, M.D., Adair, L.S., Arifeen, S.E., Ashorn, P., et al. (2013) Risk of Childhood Undernutrition Related to Small-for-Gestational Age and Preterm Birth in Lowand Middle-Income Countries. International Journal of Epidemiology, 42, 1340-1355.
http://dx.doi.org/10.1093/ije/dyt109

[35]   Oldroyd, J., Renzaho, A. and Skouteris, H. (2011) Low and High Birth Weight as Risk Factors for Obesity among 4 to 5-Year-Old Australian Children: Does Gender Matter? European Journal of Pediatrics, 170, 899-906.
http://dx.doi.org/10.1007/s00431-010-1375-4

[36]   Hirschler, V., Bugna, J., Roque, M., Gilligan, T. and Gonzalez, C. (2008) Does Low Birth Weight Predict Obesity/ Overweight and Metabolic Syndrome in Elementary School Children? Archives of Medical Research, 39, 796-802.
http://dx.doi.org/10.1016/j.arcmed.2008.08.003

[37]   Curhan, G.C., Chertow, G.M., Willett, W.C., Spiegelman, D., Colditz, G.A., Manson, J.E., et al. (1996) Birth Weight and Adult Hypertension and Obesity in Women. Circulation, 94, 1310-1315.
http://dx.doi.org/10.1161/01.CIR.94.6.1310

[38]   Eriksson, J., ForseAn, T., Tuomilehto, J., Osmond, C. and Barker, D. (2001) Size at Birth, Childhood Growth and Obesity in Adult Life. International Journal of Obesity, 25, 735-740.
http://dx.doi.org/10.1038/sj.ijo.0801602

[39]   Yu, Z.B., Han, S.P., Zhu, G.Z., Zhu, C., Wang, X.J., Cao, X.G., et al. (2011) Birth Weight and Subsequent Risk of Obesity: A Systematic Review and Meta-Analysis. Obesity Reviews, 12, 525-542.
http://dx.doi.org/10.1111/j.1467-789X.2011.00867.x

[40]   Stephen, R.D., Philip, R.K. and John, A.M. (2000) Utility of Different Measures of Body Fat Distribution in Children and Adolescents. American Journal of Epidemiology, 152, 1179-1184.
http://dx.doi.org/10.1093/aje/152.12.1179

[41]   Ibánez, L., Lopez-Bermejo, A., Suárez, L., Marcos, M.V., Díaz, M. and de Zegher, F. (2008) Visceral Adiposity without Overweight in Children Born Small for Gestational Age. The Journal of Clinical Endocrinology Metabolism, 93, 2079-2083.
http://dx.doi.org/10.1210/jc.2007-2850

 
 
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