Focal nodular hyperplasia (FNH) is a common benign hepatic tumor which is often treated non-operatively until it appears apparent symptoms such as pain and upper abdominal distension. We report here a case of trans-catheter arterial embolization (TAE) using pingyangmycin-lipiodol emulsion (PLE) for blocking a fatal bleeding originated from percutaneous biopsy as well as for FNH treatment. After embolization by means of the mixture of PLE and particles of gelfoam, the bleeding was stopped and the FNH was apparently shrinked 1 year later. TAE using PLE may be considered as a safe and effective method for the treatment of FNH.
Cite this paper
Qiu, J. , Wen, S. , Luo, L. , Chen, P. and Guo, W. (2015) Transarterial Embolization Using Pingyangmycin-Lipiodol Emulsion (PLE) for Treatment of Focal Nodular Hyperplasia of the Liver and 1-Year Follow-Up: A Case Report and Literature Review. Case Reports in Clinical Medicine
, 1-5. doi: 10.4236/crcm.2015.41001
 Navarro, A.P., Gomez, D., Lamb, C.M., Brooks, A. and Cameron, I.C. (2014) Focal Nodular Hyperplasia: A Review of Current Indications for and Outcomes of Hepatic Resection. HPB (Oxford), 16, 503-511. http://dx.doi.org/10.1111/hpb.12169
 Cha, D.I., Yoo, S.Y., Kim, J.H., Jeon, T.Y. and Eo, H. (2014) Clinical and Imaging Features of Focal Nodular Hyperplasia in Children. American Journal of Roentgenology, 202, 960-965. http://dx.doi.org/10.2214/AJR.13.11856
 Huang, D., Chen, Y., Zeng, Q., Zhao, J., Wu, R., et al. (2011) Transarterial Embolization Using Pingyangmycin Lipiodol Emulsion and Polyvinyl Alcohol for the Treatment of Focal Nodular Hyperplasia of the Liver. Hepatogastroenterology, 58, 1736-1741. http://dx.doi.org/10.5754/hge11174
 Donadon, M., Di Tommaso, L., Roncalli, M. and Torzilli, G. (2013) Multiple Focal Nodular Hyperplasias Induced by Oxaliplatin-Based Chemotherapy. World Journal of Hepatology, 5, 340-344.
 Pupulim, L.F., Vullierme, M.P., Paradis, V., Valla, D., Terraz, S., et al. (2013) Congenital Portosystemic Shunts Associated with Liver Tumours. Clinical Radiology, 68, e362-e369. http://dx.doi.org/10.1016/j.crad.2013.01.024
 Ronot, M. and Vilgrain, V. (2014) Imaging of Benign Hepatocellular Lesions: Current Concepts and Recent Updates. Clinics and Research in Hepatology and Gastroenterology, 38, 681-688.
 Carrafiello, G., Lagana, D., Ianniello, A., Craparo, G., Recaldini, C., et al. (2007) Bleeding after Percutaneous Radio Frequency Ablation: Successful Treatment with Transcatheter Embolization. European Journal of Radiology, 61, 351-355. http://dx.doi.org/10.1016/j.ejrad.2006.10.001
 Chen, W.L., Huang, Z.Q., Zhang, D.M. and Chai, Q. (2010) Percutaneous Sclerotherapy of Massive Venous Malformations of the Face and Neck Using Fibrin Glue Combined with OK-432 and Pingyangmycin. Head Neck, 32, 467-472.
 Gu, L., Huang, D.Y., Fu, C.J., Wang, Z.L., Liu, Y., et al. (2013) Intralesional Injection of Pingyangmycin plus Corticosteroids May Be an Effective Treatment for Cheilitis Granulomatosa. Medical Hypotheses, 81, 729-730. http://dx.doi.org/10.1016/j.mehy.2013.07.037
 Zeng, Q., Li, Y., Chen, Y., Ouyang, Y., He, X., et al. (2004) Gigantic Cavernous Hemangioma of the Liver Treated by Intra-Arterial Embolization with Pingyangmycin-Lipiodol Emulsion: A Multi-Center Study. CardioVascular and Interventional Radiology, 27, 481-485. http://dx.doi.org/10.1007/s00270-003-2754-2