OJOG  Vol.5 No.1 , January 2015
Morden Management of Inflammatory Bowel Disease in Pregnancy: A Practical Review for Obstetricians
Author(s) Papa Essilfie*
ABSTRACT

Inflammatory bowel disease (IBD) is a chronic, sometimes debilitating condition that affects mainly the young population. The effect of IBD on pregnancy is therefore an important clinical issue. Many Obstetricians are likely to come across the occasional patient with this chronic condition. The following article discusses the salient factors which need to be considered in pregnant women with IBD and serves as a quick, practical but nevertheless comprehensive guide for the practicing Obstetrician.


Cite this paper
Essilfie, P. (2015) Morden Management of Inflammatory Bowel Disease in Pregnancy: A Practical Review for Obstetricians. Open Journal of Obstetrics and Gynecology, 5, 5-13. doi: 10.4236/ojog.2015.51002.
References
[1]   Podolsky, D.K. (2002) Inflammatory Bowel Disease. New England Journal of Medicine, 347, 417-428.
http://dx.doi.org/10.1056/NEJMra020831

[2]   Conses, J., Beaugerie, L., Carbornnel, F. and Gendre, J.P. (2001) Smoking Cessation and the Course of Crohn’s Disease: An Intervention Study. Gastroenterology, 120, 1093-1099.
http://dx.doi.org/10.1053/gast.2001.23231

[3]   Lindberg, E., Tysk, C., Anderson, K. and Jarnerot, G. (1988) Smoking and Inflammatory Bowel Disease: A Case Control Study. Gut, 29, 352-357. http://dx.doi.org/10.1136/gut.29.3.352

[4]   Susie, W.Ng. and Mahedevan, U. (2013) Management of Inflammatory Bowel Disease in Pregnancy. Expert Rev. Clin. Immunol, 9, 161-174.

[5]   Biederman, L., Rogler, G., Varvricka, S.R., Siebold, F. and Seirafi, M. (2012) Pregnancy and Breastfeeding in Inflammatory Bowel Disease. Digestion, 86, 45-54. http://dx.doi.org/10.1159/000341941

[6]   Kane, S., Kisiel, J., Shih, L., et al. (2004) HLA Disparity Determines Disease Activity through Pregnancy in Women with Inflammatory Bowel Disease. The American Journal of Gastroenterology, 99, 1523-1526. http://dx.doi.org/10.1111/j.1572-0241.2004.30472.x

[7]   Kwan, L.Y. and Mahedevan, U. (2010) Inflammatory Bowel Disease and Pregnancy: An Update. Expert Review of Clinical Immunology, 6, 643-657. http://dx.doi.org/10.1586/eci.10.35

[8]   Bush, M.C., Patel, S., Lapinski, R.H. and Stone, J.L. (2004) Perinatal Outcomes in Inflammatory Bowel Disease. The Journal of Maternal-Fetal and Neonatal Medicine, 15, 237-241.
http://dx.doi.org/10.1080/14767050410001668662

[9]   Sutherland, L., Singleton, J., Sessions, J., et al. (1991) Double Blind, Placebo Controlled Trial of Metronidazole in Crohn’s Disease. Gut, 32, 1071-1075.

[10]   Bar Oz, B., Hackman, R., Einarson, T., et al. (2001) Pregnancy Outcome after Cyclosporin Therapy during Pregnancy: A Metanalysis. Transplantation, 71, 1051-1055.
http://dx.doi.org/10.1097/00007890-200104270-00006

[11]   Ilnyckyji, A., Blanchard, J.F., Rawsthorne, P., et al. (1999) Perianal Crohn’s Disease and Pregnancy: Role of Mode of Delivery. The American Journal of Gastroenterology, 94, 3274-3278.

[12]   Podolsky, D.K. (2002) Inflammatory Bowel Disease. New England Journal of Medicine, 347, 417-428. http://dx.doi.org/10.1056/NEJMra020831

[13]   Conses, J., Beaugerie, L., Carbornnel, F. and Gendre, J.P. (2001) Smoking Cessation and the Course of Crohn’s Disease: An Intervention Study. Gastroenterology, 120, 1093-1099.
http://dx.doi.org/10.1053/gast.2001.23231

[14]   Lindberg, E., Tysk, C., Anderson, K. and Jarnerot, G. (1988) Smoking and Inflammatory Bowel Disease: A Case Control Study. Gut, 29, 352-357. http://dx.doi.org/10.1136/gut.29.3.352

[15]   Susie, W.Ng. and Mahedevan, U. (2013) Management of Inflammatory Bowel Disease in Pregnancy. Expert Rev. Clin. Immunol, 9, 161-174.

[16]   Biederman, L., Rogler, G., Varvricka, S.R., Siebold, F. and Seirafi, M. (2012) Pregnancy and Breastfeeding in Inflammatory Bowel Disease. Digestion, 86, 45-54. http://dx.doi.org/10.1159/000341941

[17]   Kane, S., Kisiel, J., Shih, L., et al. (2004) HLA Disparity Determines Disease Activity through Pregnancy in Women with Inflammatory Bowel Disease. The American Journal of Gastroenterology, 99, 1523-1526. http://dx.doi.org/10.1111/j.1572-0241.2004.30472.x

[18]   Kwan, L.Y. and Mahedevan, U. (2010) Inflammatory Bowel Disease and Pregnancy: An Update. Expert Review of Clinical Immunology, 6, 643-657. http://dx.doi.org/10.1586/eci.10.35

[19]   Bush, M.C., Patel, S., Lapinski, R.H. and Stone, J.L. (2004) Perinatal Outcomes in Inflammatory Bowel Disease. The Journal of Maternal-Fetal and Neonatal Medicine, 15, 237-241.
http://dx.doi.org/10.1080/14767050410001668662

[20]   Sutherland, L., Singleton, J., Sessions, J., et al. (1991) Double Blind, Placebo Controlled Trial of Metronidazole in Crohn’s Disease. Gut, 32, 1071-1075.

[21]   Bar Oz, B., Hackman, R., Einarson, T., et al. (2001) Pregnancy Outcome after Cyclosporin Therapy during Pregnancy: A Metanalysis. Transplantation, 71, 1051-1055.
http://dx.doi.org/10.1097/00007890-200104270-00006

[22]   Ilnyckyji, A., Blanchard, J.F., Rawsthorne, P., et al. (1999) Perianal Crohn’s Disease and Pregnancy: Role of Mode of Delivery. The American Journal of Gastroenterology, 94, 3274-3278.

 
 
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