References
[1] Folts, J.D. (2002) Potential Health Benefits from the Flavonoids in Grape Products on Vascular Disease. Advances in Experimental Medicine and Biology, 505, 95-111.
http://dx.doi.org/10.1007/978-1-4757-5235-9_9
[2] Chaves, A.A., Joshi, M.S., Coyle, C.M., Brady, J.E., Dech, S.J., Schanbacher, B.L., Baliga, R., Basuray, A. and Bauer, J.A. (2009) Vasoprotective Endothelial Effects of a Standardized Grape Product in Humans. Vascular Pharmacology, 50, 20-26.
http://dx.doi.org/10.1016/j.vph.2008.08.004
[3] Bagchi, D., Bagchi, M., Stohs, S.J., Das, D.K., Ray, S.D., Kuszynski, C.A., Joshi, S.S. and Pruess, H.G. (2000) Free Radicals and Grape Seed Proanthocyanidin Extract: Importance in Human Health and Disease Prevention. Toxicology, 148, 187-197.
http://dx.doi.org/10.1016/S0300-483X(00)00210-9
[4] Goncalves, T.L., Benvegnu, D.M., Bonfanti, G., Frediani, A.V. and Rocha J.B. (2009) Delta-ALA-D Activity Is a Reliable Marker for Oxidative Stress in Bone Marrow Transplant Patients. BMC Cancer, 9, 138.
http://dx.doi.org/10.1186/1471-2407-9-138
[5] Conklin, K.A. (2000) Dietary Antioxidants during Cancer Chemotherapy: Impact on Chemotherapeutic Effectiveness and Development of Side Effects. Nutrition and Cancer, 37, 1-18.
http://dx.doi.org/10.1207/S15327914NC3701_1
[6] Conklin, K.A. (2004) Chemotherapy-Associated Oxidative Stress: Impact on Chemotherapeutic Effectiveness. Integrative Cancer Therapies, 3, 294-300.
http://dx.doi.org/10.1177/1534735404270335
[7] Wessner, B., Strasser, E.M., Koitz, N., Schmuckenschlager, C., Unger-Manhart, N. and Roth, E. (2007) Green Tea Polyphenol Administration Partly Ameliorates Chemotherapy Induced Side Effects in the Small Intestine of Mice. Journal of Nutrition, 137, 634-64.
[8] Li, W., Xu, B., Xu, J. and Wu, X.L. (2009) Procyanidins Produce Significant Attenuation of Doxorubicin-Induced Cardiotoxicity via Suppression of Oxidative Stress. Basic Clinical Pharmacology Toxicology, 104, 192-197.
http://dx.doi.org/10.1111/j.1742-7843.2008.00358.x
[9] Minotti, G., Menna, P., Salvatorelli, E., Cairo, G. and Gianni, L. (2004) Anthracyclines: Molecular Advances and Pharmacologic Developments in Antitumor Activity and Cardiotoxicity. Pharmacological Reviews, 56, 185-229.
http://dx.doi.org/10.1124/pr.56.2.6
[10] Takemura, G. and Fujiwara, H. (2007) Doxorubicin-Induced Cardiomyopathy from the Cardiotoxic Mechanisms to Management. Progress in Cardiovascular Diseases, 49, 330-352.
http://dx.doi.org/10.1016/j.pcad.2006.10.002
[11] Davies, K.J. and Doroshow, J.H. (1986) Redox Cycling of Anthracyclines by Cardiac Mitochondria. I. Anthracycline Radical Formation by NADH Dehydrogenase. Journal of Biological Chemistry, 261, 3060-3067.
[12] Doroshow, J.H. (1983) Anthracycline Antibiotic-Stimulated Superoxide, Hydrogen Peroxide and Hydroxyl Radical Production by NADH Dehydrogenase. Cancer Research, 43, 4543-4551.
[13] Ferraro, C., Quemeneur, L., Prigent, A.F., Taverne, C., Revillard, J.P. and Bonnefoy-Berard, N. (2000) Anthracyclines Trigger Apoptosis of both G0 - G1 and Cycling Peripheral Blood Lymphocytes and Induce Massive Deletion of Mature T and B Cells. Cancer Research, 60, 1901-1907.
[14] Goodman, J. and Hochstein, P. (1977) Generation of Free Radicals and Lipid Peroxidation by Redox Cycling of Adriamycin and Daunomycin. Biochemical and Biophysical Research Communications, 77, 797-803.
http://dx.doi.org/10.1016/S0006-291X(77)80048-X
[15] Nakano, H., Ogita, K., Gutteridge, J.C. and Nakano, M. (1984) Inhibition by the Protein Ceruloplasmin of Lipid Peroxidation Stimulated by an Fe3+-ADP-Adriamycin Complex. FEBS Letters, 166, 232-236.
[16] Zweier, J.L. (1984) Reduction of O2 by Iron-Adriamycin. Journal of Biological Chemistry, 259, 6056-6058.
[17] Sonneveld, P. (1978) Effect of Alpha-Tocopherol on the Cardiotoxicity of Adriamycin in the Rat. Cancer Treatment Reports, 62, 1033-1036.
[18] Villani, F., Galimberti, M., Monti, E., Piccinini, F., Lanza, E., Rozza, A., et al. (1990) Effect of Glutathione and N-Acetylcysteine on in Vitro and in Vivo Cardiac Toxicity of Doxorubicin. Free Radical Research, 11, 145-115.
http://dx.doi.org/10.3109/10715769009109677
[19] Cui, J., Cordis, G.A., Tosaki, A., Maulik, N. and Das, D.K. (2002) Reduction of Myocardial Ischemia Reperfusion Injury with Regular Consumption of Grapes. Annals of the New York Academy of Sciences, 957, 302-307.
http://dx.doi.org/10.1111/j.1749-6632.2002.tb02930.x
[20] Bagchi, D., Ray, S.D., Patel, D. and Bagchi, M. (2001) Protection against Drug- and Chemical-Induced Multiorgan Toxicity by a Novel IH636 Grape Seed Proanthocyanidin Extract. Drugs under Experimental and Clinical Research, 27, 3-15.
[21] Bagchi, D., Ray, S.D., Bagchi, M., Preuss, H.G. and Stohs, S.J. (2002) Mechanistic Pathways of Antioxidant Cytoprotection by a Novel IH636 Grape Seed Proanthocyanidin Extract. Indian Journal of Experimental Biology, 40, 717-726.
[22] Kline, K., Yu, W. and Sanders, B.G. (2004) Vitamin E and Breast Cancer. Journal of Nutrition, 134, 3458S-3462S.
[23] Brigelius-Flohe, R., Kelly, F.J., Salonen, J.T., Neuzil, J., Zingg, J.M. and Azzi, A. (2002) The European Perspective on Vitamin E: Current Knowledge and Future Research. American Journal of Clinical Nutrition, 76, 703-716.
[24] Peralta, E.A., Viegas, M.L., Louis, S., Engle, D.L. and Dunnington, G.L. (2006) Effect of Vitamin E on Tamoxifen-Treated Breast Cancer Cells. Surgery, 140, 607-615.
http://dx.doi.org/10.1016/j.surg.2006.07.007
[25] Pace, A., Savarese, A., Picardo, M., Maresca, V., Pacetti, U., Del Monte, G., Biroccio, A., Leonetti, C., Jandolo, B., Cognetti, F. and Bove, L. (2003) Neuroprotective Effect of Vitamin E Supplementation in Patients Treated with Cisplatin Chemotherapy. Journal of Clinical Oncology, 21, 927-931.
http://dx.doi.org/10.1200/JCO.2003.05.139
[26] Sultana, N., Begum, N., Begum, S., Ferdousi, S. and Ali, T. (2006) Effects of Vitamin E Supplementation on Some Aspects of Hematological Variables in Patients of Hemolytic Anemia with Glucose 6 Phosphate Dehydrogenase (G6PD) Deficiency. Bangladesh Journal of Physiology and Pharmacology, 22, 12-17.
[27] Pataki, T., Bak, I., Kovacs, P., Bagchi, D., Das, D.K. and Tosaki, A. (2002) Grape Seed Pro-Anthocyanidins Improved Cardiac Recovery during Reperfusion after Ischemia in Isolated Rat Hearts. American Journal of Clinical Nutrition, 75, 894-899.
[28] Deeg, R. and Ziegenhorn, J. (1983) Kinetic Enzymic Method for Automated Determination of Total Cholesterol in Serum. Clinical Chemistry, 29, 1798-1802.
[29] Okada, M., Matsui, H., Ito, Y., Fujiwara, A. and Inano, K. (1998) Low-Density Lipoprotein Cholesterol Can Be Chemically Measured: A New Superior Method. Journal of Laboratory and Clinical Medicine, 132, 195-201.
http://dx.doi.org/10.1016/S0022-2143(98)90168-8
[30] Durrington, P.N. and Paul Miller, J. (1982) High-Density Lipoprotein Cholesterol: Methods and Clinical Significance. Critical Reviews in Clinical Laboratory Sciences, 18, 31-78.
http://dx.doi.org/10.3109/10408368209082589
[31] Howdieshell, T.R., Bhalla, N., DiPiro, J.T., Kuske, T. and Baisden, R. (1995) Effects of Free Glycerol Contained in Intravenous Fat Emulsion on Plasma Triglyceride Determination. JPEN Journal of Parenteral and Enteral Nutrition, 19, 125-126.
http://dx.doi.org/10.1177/0148607195019002125
[32] Smith, A.F. and Taylor, R.H. (1972) Comparison of Two-Point (AutoAnalyzer II) with Kinetic Methods for Transaminase Assay. Journal of Clinical Pathology, 26, 42-47.
http://dx.doi.org/10.1136/jcp.26.1.42
[33] Menon, M.P., Anderson, G. and Namblar, G.K. (1983) Determination of Human Serum Lactate Dehydrogenase Isoenzymes by Anion Exchange Chromatography. Analytical Chemistry, 55, 1385-1390.
http://dx.doi.org/10.1021/ac00259a044
[34] Gjerde, H. and Mørland, J. (1985) Determination of Gamma Glutamyltransferase in Completely Haemolysed Blood Samples. Scandinavian Journal of Clinical & Laboratory Investigation, 45, 661-664.
http://dx.doi.org/10.3109/00365518509155275
[35] Nandi, A. and Chatterjee, I.B. (1988) Assay of Superoxide Dismutase Activity in Animal Tissues. Journal of Biosciences, 13, 305-315.
http://dx.doi.org/10.1007/BF02712155
[36] Lukaszewicz-Hussain, A. and Moniuszko-Jakoniuk, J. (2004) Liver Catalase, Glutathione Peroxidase and Reductase Activity, Reduced Glutathione and Hydrogen Peroxide Levels in Acute Intoxication with Chlorfenvinphos, an Organophosphate Insecticide. Polish Journal of Environmental Studies, 13, 303-309.
[37] Allison, G.W., Perla, R.J., Belliveau, P.P. and Angelis, S.M. (2009) Elevated Creatine Phosphokinase Levels Associated with Linezolid Therapy. American Journal of Health-System Pharmacy, 66, 1097-1100.
http://dx.doi.org/10.2146/ajhp080228
[38] Park, W., Kim, B.S., Lee, J.E., Huh, J.K., Kim, B.J., Sung, K.C., Kang, J.H., Lee, M.H., Park, J.R., Rhee, E.J., Oh, K.W., Lee, W.Y., Park, C.Y., Park, S.W. and Kim, S.W. (2009) Serum Phosphate Levels and the Risk of Cardiovascular Disease and Metabolic Syndrome: A Double-Edged Sword. Diabetes Research and Clinical Practice, 83, 119-125.
http://dx.doi.org/10.1016/j.diabres.2008.08.018
[39] Lenaz, G., Bertoli, E., Curatola, G., Mazzanti, L. and Bigi, A. (1976) Lipid Protein Interactions in Mitochondria: Spin and Fluorescence Probe Studies on the Effect of n-Alkanols on Phospholipid Vesicles and Mitochondrial Membranes. Archives of Biochemistry and Biophysics, 172, 278-288.
http://dx.doi.org/10.1016/0003-9861(76)90077-1
[40] Jensen, R.A., Acton, E.M. and Peters, J.H. (1984) Doxorubicin Cardiotoxicity in the Rat: Comparison of Electrocardiogram, Transmembrane Potential, and Structural Effects. Journal of Cardiovascular Pharmacology, 6, 186-200.
http://dx.doi.org/10.1097/00005344-198401000-00028
[41] Droshow, J.H. (1983) Effect of Anthracycline Anti-biotics on Oxygen Radical Formation in Rat Heart. Cancer Research, 43, 460-472.
[42] Ferrans, V.J. (1978) Overview of Cardiac Pathology in Relation to Anthracycline Cardiotoxicity. Cancer Treatment Reports, 62, 955-961.
[43] Olson, R.D., Boerth, R.C., Gerber, J.G. and Nies, A.S. (1981) Mechanism of Adriamycin Cardiotoxicity: Evidence for Oxidative Stress. Life Sciences, 29, 1393-1401.
http://dx.doi.org/10.1016/0024-3205(81)90001-1
[44] Stohs, S.J. (1995) The Role of Free Radicals in Toxicity and Disease. Journal of Basic and Clinical Physiology and Pharmacology, 6, 205-228.
http://dx.doi.org/10.1515/JBCPP.1995.6.3-4.205
[45] Cadenas, E. and Packer, L. (2002) Handbook of Antioxidants. 2nd Edition, Marcel Dekker, Inc., New York.
[46] Liu, S.Q., Yu, J.P., Chen, H.L., Luo, H.S., Chen, S.M. and Yu, H.G. (2006) Therapeutic Effects and Molecular Mechanisms of Ginkgo Biloba Extract on Liver Fibrosis in Rats. American Journal of Chinese Medicine, 34, 99-114.
http://dx.doi.org/10.1142/S0192415X06003679
[47] Ichikawa, H., Wang, L. and Konishi, T. (2006) Prevention of Cerebral Oxidative Injury by Post-Ischemic Intravenous Administration of Shengmai San. American Journal of Chinese Medicine, 34, 591-600.
http://dx.doi.org/10.1142/S0192415X06004120
[48] Chang, W.T., Shao, Z.H., VandenHoek, T.L., McEntee, E., Mehendale, S.R., Li, J., Becker, L.B. and Yuan, C.S. (2006) Cardioprotective Effects of Grape Seed Proanthocyanidins, Baicalin and Wogonin: Comparison between Acute and Chronic Treatments. American Journal of Chinese Medicine, 34, 363-365.
[49] Lee, C.Y., Peng, W.H., Cheng, H.Y., Chen, F.N., Lai, M.T. and Chiu, T.H. (2006) Hepatoprotective Effect of Phyllanthus in Taiwan on Acute Liver Damage Induced by Carbon Tetrachloride. American Journal of Chinese Medicine, 34, 471-482.
http://dx.doi.org/10.1142/S0192415X06004004
[50] Chung, S.Y., Cheng, F.C., Lee, M.S., Lin, J.Y., Lin, M.C. and Wang, M.F. (2006) Ginkgo biloba Leaf Extract (EGb761) Combined with Neuroprotective Agents Reduces the Infarct Volumes of Gerbil Ischemic Brain. American Journal of Chinese Medicine, 34, 803-817.
http://dx.doi.org/10.1142/S0192415X06004302
[51] Yang, J.H., Tsai, S.Y., Han, C.M., Shih, C.C. and Mau, J.L. (2006) Antioxidant Properties of Glossogyne tenuifolia. American Journal of Chinese Medicine, 34, 707-720.
http://dx.doi.org/10.1142/S0192415X06004223
[52] Choi, J., Conrad, C.C., Malakowsky, C.A., Talent, J.M., Yuan, C.S. and Gracy, R.W. (2002) Flavones from Scutellaria baicalensis Georgi Attenuate Apoptosis and Protein Oxidation in Neuronal Cell Lines. Biochimica et Biophysica Acta, 1571, 201-210.
http://dx.doi.org/10.1016/S0304-4165(02)00217-9
[53] Hamada, H., Hiramatsu, M., Edamatsu, R. and Mori, A. (1993) Free Radical Scavenging Action of Baicalein. Archives of Biochemistry and Biophysics, 306, 261-266.
http://dx.doi.org/10.1006/abbi.1993.1509
[54] Stangl, V., Lorenz, M. and Stangl, K. (2006) The Role of Tea and Tea Flavonoids in Cardiovascular Health. Molecular Nutrition & Food Research, 50, 218-228.
http://dx.doi.org/10.1002/mnfr.200500118
[55] Dalton, T.P., Shertzer, H.G. and Puga, A. (1999) Regulation of Gene Expression by Reactive Oxygen. Annual Review of Pharmacology and Toxicology, 39, 67-101.
http://dx.doi.org/10.1146/annurev.pharmtox.39.1.67
[56] Park, C., So, H.S., Kim, S.J., Youn, M.J., Moon, B.S., Shin, S.H., Lee, I., Moon, S.K. and Park, R. (2006) Samul Extract Protects against the H2O2-Induced Apoptosis of H9c2 Cardiomyoblasts via Activation of Extracellular Regulated Kinases (Erk) 1/2. American Journal of Chinese Medicine, 34, 695-706.
http://dx.doi.org/10.1142/S0192415X06004211
[57] Ray, S., Bagchi, D., Lim, P.M., Bagchi, M., Gross, S.M., Kothari, S.C., Preuss, H.G. and Stohs, S.J. (2001) Acute and Long-Term Safety Evaluation of a Novel IH636 Grape Seed Proanthocyanidin Extract. Research Communications in Molecular Pathology and Pharmacology, 109, 165-197.
[58] Wang, C.Z., Fishbein, A., Aung, H.H., Mehendale, S.R., Chang, W.T., Xie, J.T., Li, J. and Yuan, C.S. (2005) Polyphenol Contents in Grape-Seed Extracts Correlate with Antipica Effects in Cisplatin-Treated Rats. Journal of Alternative and Complementary Medicine, 11, 1059-1065.
http://dx.doi.org/10.1089/acm.2005.11.1059
[59] Rimm, E.B., Giovannucci, E.L., Willett, W.C., Colditz, G.A., Ascherio, A., Rosner, B. and Stampfer, M.J. (1991) Prospective Study of Alcohol Consumption and Risk of Coronary Disease in Men. Lancet, 338, 464-468.
http://dx.doi.org/10.1016/0140-6736(91)90542-W
[60] Hosny, M. and Rosazza, J.P. (2002) Novel Oxidations of (+)-Catechin by Horseradish Peroxidase and Laccase. Journal of Agricultural and Food Chemistry, 50, 5539-5545.
http://dx.doi.org/10.1021/jf020503j
[61] Yang, H.L., Hseu, Y.C., Chen, J.Y., Yech, Y.J., Lu, F.J., Wang, H.H., Lin, P.S. and Wang, B.C. (2006) Antrodia camphorata in Submerged Culture Protects Low Density Lipoproteins against Oxidative Modification. American Journal of Chinese Medicine, 34, 217-231.
http://dx.doi.org/10.1142/S0192415X06003783
[62] Bagchi, D., Garg, A., Krohn, R.L., Bagchi, M., Bagchi, D.J., Balmoori, J. and Stohs, S.J. (1998) Protective Effects of Grape Seed Proanthocyanidins and Selected Antioxidants against TPA-Induced Hepatic and Brain Lipid Peroxidation and DNA Fragmentation, and Peritoneal Macrophage Activetion in Mice. General Pharmacology, 30, 771-776.
http://dx.doi.org/10.1016/S0306-3623(97)00332-7
[63] Yamaguchi, F., Yoshimura, Y., Nakazawa, H. and Ariga, T. (1999) Free Radical Scavenging Activity of Grape Seed Extract and Antioxidants by Electron Spin Resonance Spectrometry in an H2O2/NaOH/DMSO System. Journal of Agricultural and Food Chemistry, 47, 2544-2548.
http://dx.doi.org/10.1021/jf9806762
[64] Joshi, S.S., Kuszynski, C.A., Benner, E.J., Bagchi, M. and Bagchi, D. (1999) Amelioration of the Cytotoxic Effects of Chemotherapeutic Agents by Grape Seed Proanthocyanidin Extract. Antioxidants & Redox Signaling, 1, 563-570.
http://dx.doi.org/10.1089/ars.1999.1.4-563
[65] Ray, S.D., Patel, D., Wong, V. and Bagchi, D. (2000) In Vivo Protection of DNA Damage Associated Apoptotic and Necrotic Cell Deaths during Acetaminophen-Induced Nephrotoxicity, Amiodarone-Induced Lung Toxicity and Doxorubicin-Induced Cardiotoxicity by a Novel IH636 Grape Seed Proanthocyanidin Extract. Research Communications in Molecular Pathology and Pharmacology, 107, 137-166.
[66] Chis, I.C., Ungureanu, M.I., Marton, A., Simedrea, R., Muresan, A., Postescu, I.D. and Decea, N. (2009) Antioxidant Effects of a Grape Seed Extract in a Rat Model of Diabetes Mellitus. Diabetes & Vascular Disease Research, 6, 200-204.
[67] Geetha, A., Marar, T. and Devi, C.S. (1991) Effect of Alpha-Tocopherol on Doxorubicin-Induced Changes in Rat Liver and Heart Microsomes. Indian Journal of Experimental Biology, 29, 782-785.