OJOph  Vol.4 No.4 , November 2014
Is There a Role for Intravitreal Triamcinolone Acetonide Injection in the Treatment of Purtscher-Like Retinopathy? Report of Two Cases
ABSTRACT
We hereby described two cases with unilateral Purtscher-like retinopathy. The first case occurred following an uneventful spontaneous vaginal delivery. The second case had no discernable cause despite having meticulous systemic work-up. Both eyes had low presenting visual acuity of hand movements and 20/200 consecutively. We elected to inject 1 mg triamcinolone acetolamide in-travitreally for the treatment. Though, there was some subjective visual and clinical improvement within time in both patients, we were not convinced that intravitreal injection was superior to no treatment approach.

Cite this paper
Doruk, H. , Saatci, A. and Yaman, A. (2014) Is There a Role for Intravitreal Triamcinolone Acetonide Injection in the Treatment of Purtscher-Like Retinopathy? Report of Two Cases. Open Journal of Ophthalmology, 4, 145-150. doi: 10.4236/ojoph.2014.44023.
References
[1]   Purtscher, O. (1910) Noch Unbekannte Befunde Nach Schadeltrauma. Bericht Uber Die Zusammenkunft Der Deutschen Ophthalmologischen Gesellschaft, 36, 294-301.

[2]   Miguel, A.I.M., Henriques, F., Azevedo, L.F.R., Lourerio, A.J. and Maberley, D.A.L. (2013) Systematic Review of Purtscher’s and Purtscher-Like Retinopathies. Eye, 27, 1-13.
http://dx.doi.org/10.1038/eye.2012.222

[3]   Agrawal, A. and McKibbin, M.A. (2006) Purtscher’s and Purtscher-Like Retinopathies: A Review. Survey of Ophthalmology, 51, 129-136.
http://dx.doi.org/10.1016/j.survophthal.2005.12.003

[4]   Kincaid, M.C., Green, W.R., Knox, D.L. and Mohler, C. (1982) A Clinicopathological Case Report of Retinopathy of Pancreatitis. British Journal of Ophthalmology, 66, 219-226.
http://dx.doi.org/10.1136/bjo.66.4.219

[5]   Hammerschmidt, D.E., White, J.G., Craddock, P.R. and Jacob, H.S. (1979) Corticosteroids Inhibit Complement-Induced Granulocyte Aggregation. A Possible Mechanism for Their Efficacy in Shock States. Journal of Clinical Investigation, 63, 798-803.
http://dx.doi.org/10.1172/JCI109365

[6]   Goldstein, I.M., Roos, D., Weisman, G. and Kaplan, H.B. (1976) Influence of Corticosteroid on Human Polymorphonuclear Leukocyte Function in Vitro: Reaction of Lysosomal Enzyme Release and Superoxide Production. Inflammation, 1, 305-315.
http://dx.doi.org/10.1007/BF00917870

[7]   Wang, A.G., Yen, M.Y. and Liu, J.H. (1998) Pathogenesis and Neuroprotective Treatment in Purtscher’s Retinopathy. Japanese Journal of Ophthalmology, 42, 318-322.
http://dx.doi.org/10.1016/S0021-5155(98)00015-X

[8]   Atabay, C., Kansu, T. and Nurlu, G. (1993) Late Visual Recovery after Intravenous Methylprednisolone Treatment of Purtscher’s Retinopathy. Annals of Ophthalmology, 25, 330-333.

[9]   Zwolińska, D., Medyńska, A., Galar, A. and Turno, A. (2000) Purtscher-Like Retinopathy in Nephrotic Syndrome Associated with Mild Chronic Renal Failure. Pediatric Nephrology, 15, 82-84.

[10]   Cumurcu, T., Yardim, H., Güven, M., Kiliç, R. and Ozkan, N. (2008) Purtscher’s Retinopathy: An Unusual Association with a Complicated Mandibular Fracture. Turkish Journal of Medical Sciences, 38, 373-376.

[11]   Yan, Y. and Shen, X. (2013) Purtscher-Like Retinopathy Associated with Dermatomyositis. BMC Ophthalmology, 13, 36.
http://dx.doi.org/10.1186/1471-2415-13-36

[12]   Olson, J., Rouhani, B. and Mandava, N. (2008) Sub-Tenon’s Triamcinolone for Post-Partum Purtscher’s-Like Retinopathy. Clinical Ophthalmology, 2, 195-198.
http://dx.doi.org/10.2147/OPTH.S2080

 
 
Top