OJRA  Vol.4 No.4 , November 2014
A Rare Case of Gastric Linitis Plastica Revealed by Isolated Vertebral Metastases in a Young Woman in a Less Developed Country
Abstract: Aim: We report a rare case of gastric linitis plastica revealed by vertebral metastases without another digestive dissemination. Case presentation: The Benin native woman was hospitalized in rheumatology for inflammatory back pain without another signs. Rx ray showed vertebra metastasis. In the etiologic research, gastroscopy showed an infiltrating lesion of the antral area, indicating gastric linitis which was confirmed by biopsy. Short and medium-term evolution was favourable, characterized by a complete disappearance of the pains and a good physical condition. Conclusion: Vertebral metastases can reveal digestive cancer, although human gut is not among the most bone metastatic cancers.
Cite this paper: Zomalheto, Z. , Kpossou, R. , Agbodande, A. and Larbre, J. (2014) A Rare Case of Gastric Linitis Plastica Revealed by Isolated Vertebral Metastases in a Young Woman in a Less Developed Country. Open Journal of Rheumatology and Autoimmune Diseases, 4, 207-211. doi: 10.4236/ojra.2014.44028.

[1]   Alcalay, M., Azais, I., Brigeon, B., Babin, P., Vandermarcq, P., Debiais, F. and Bontoux, D. (1995) Strategy for Identifying Primary Malignancies with Inaugural Bone Metastases. Revue du Rhumatisme (English ed.), 62, 632-642

[2]   Vandecandelaere, M., Flipo, R.M., Cortet, B., Catanzariti, L., Duquesnoy, B. and Delcambre, B. (2004) Bone Metastases Revealing Primary Tumors. Comparison of Two Series Separated by 30 Years. Joint Bone Spine, 71, 224-229.

[3]   Karila-Cohen, P., Petit, T., Hotobi, H. and Merran, S. (2004) Gastric Leiomyosarcoma. Journal of Radiology, 85, 1993-1997.

[4]   Destombes, C., Botton, E., Le Gal, G., et al. (2007) Investigations for Bone Metastasis from an Unknown Primary. Joint Bone Spine, 74, 85-89.

[5]   Zagame, L., Boige, V., Malka, D., Fallik, D., Pocard, M., Villing, A.L., et al. (2004) Gastric Linitis Metastases: Descriptive and Prognostic Study. Clinical and Biological Gastroenterology. 1st Edition, Masson, Paris, A199.

[6]   Walker, M.J. (1996) A Review of Carcinoma of the Stomach at a Tertiary Care Referral Hospital. The American Journal of Surgery, 172, 75-78.

[7]   Yokoyama, T., Nakamura, H., Otani, Y., Kubota, T. and Fujimoto, N. (2004) Differences between Scirrhous and Non-Scirrhous Human Gastric Carcinoma from the Aspect of proMMP-2 Activation Regulated by TIMP-3. Clinical & Experimental Metastasis, 21, 223-233.

[8]   Kazunori, N., Masakazu, Y. and Kosei, H. (2003) Keratinocyte Growth Factor Produced by Gastric Fibroblasts Specifically Stimulates Proliferation of Cancer Cells from Scirrhous Gastric Carcinoma. Cancer Research, 63, 8848-8852.

[9]   Dussaulx-Garin, L., Blayau, M. and Pagenault, M. (2001) A New Mutation of E-Cadherin Gene in Familial Gastric Linitis Plastica Cancer with Extra-Digestive Dissemination. European Journal of Gastroenterology & Hepatology, 13, 711-775.

[10]   Mohamed, I., Beyrouti, A., Ramez, B., Ben Amara, M., Frikhaa, F., et al. (2007) Gastric Linitis. La Presse Médicale, 36, 1782-1786.

[11]   Ducreux, M., Boige, V. and Taieb, J. (2000) La linite: Une forme particulière de cancer gastrique. Mini-Revue, Hepato Gastro, 4, 263-267.

[12]   Ventura, L., Chiominto, A., Discepoli, S., Ventura, T., Di Giacomo, C. and Leocata, P. (2002) Lack of Prognostic Significance in Goseki Grading of Gastric Carcinoma. Journal of Experimental Clinical Cancer Research, 21, 225-227.

[13]   Jang, H.J, Lim, H.K., Kim, H.S., Cho, E.Y., Lee, S.J., Kim, K.A. et al. (2001) Intestinal Metastases from Gastric Adenocarcinoma: Helical CT Findings. Journal of Computer Assisted Tomography, 25, 61-67.

[14]   Descamps, V., Makhlouf, R., Katchourine, I., Grossin, M. and Belaich, S. (1995) Linitis Plastica Disclosed by Cervical Cutaneous Metastasis. Annales de Dermatologie et de Vénéréologie, 122, 108-110.