Post Liver Transplantation Lympho Proliferative Disorder, Classical Hodgkins Lymphoma Type—A Case Report
Affiliation(s)
1 Department of Pathology, Amrita Institute of Medical Sciences, Amrita Viswavidyapeetam, Kochi, India. 2 Department of Surgical Gastroenterology, Amrita Institute of Medical Sciences, Amrita Viswavidyapeetam, Kochi, India.
1 Department of Pathology, Amrita Institute of Medical Sciences, Amrita Viswavidyapeetam, Kochi, India. 2 Department of Surgical Gastroenterology, Amrita Institute of Medical Sciences, Amrita Viswavidyapeetam, Kochi, India.
ABSTRACT
Post transplantation lymphoproliferative disorder is a lymphoid/plasmacytic proliferation that develops as a consequence of immunosuppression in a recipient of a solid organ/bone marrow/stem cell allograft. The incidence reported in literature in post liver transplant patients is 1% - 2%. This case was of a 16-year-old boy who underwent liver transplantation for fulminant hepatic failure and subsequently developed PTLD. Morphologically and immunohistochemically, it was Hodgkin’s lymphoma like PTLD, which was the least common type reported in literature.
Post transplantation lymphoproliferative disorder is a lymphoid/plasmacytic proliferation that develops as a consequence of immunosuppression in a recipient of a solid organ/bone marrow/stem cell allograft. The incidence reported in literature in post liver transplant patients is 1% - 2%. This case was of a 16-year-old boy who underwent liver transplantation for fulminant hepatic failure and subsequently developed PTLD. Morphologically and immunohistochemically, it was Hodgkin’s lymphoma like PTLD, which was the least common type reported in literature.
KEYWORDS
Liver Transplant, Post Transplant Lymphoproliferative Disorder, Classical Hodgkin’s Lymphoma Like
Liver Transplant, Post Transplant Lymphoproliferative Disorder, Classical Hodgkin’s Lymphoma Like
Cite this paper
Nair, I. , Jojo, A. , Surendran, S. and Balakrishnan, D. (2014) Post Liver Transplantation Lympho Proliferative Disorder, Classical Hodgkins Lymphoma Type—A Case Report. International Journal of Clinical Medicine, 5, 1142-1145. doi: 10.4236/ijcm.2014.518146.
Nair, I. , Jojo, A. , Surendran, S. and Balakrishnan, D. (2014) Post Liver Transplantation Lympho Proliferative Disorder, Classical Hodgkins Lymphoma Type—A Case Report. International Journal of Clinical Medicine, 5, 1142-1145. doi: 10.4236/ijcm.2014.518146.
References
[1] International Agency for Research on Cancer (IARC) (2008) WHO Classification of Tumours of Hematopoietic and Lymphoid Tissues. 4th Edition. [2] Jain, A., Nalesnik, M., et al. (2002) Posttransplant Lymphoproliferative Disorders in Liver Transplantation. A 20-Year Experience. Jorge Reyes Annals of Surgery, 236, 429-437. [3] Parker, A., Bowles, K., Bradley, J.A., et al. (2010) Diagnosis of Post-Transplant Lymphoproliferative Disorder in Solid Organ Transplant Recipients—BCSH and BTS Guidelines. British Journal of Haematology, 149, 675-692.
[1] International Agency for Research on Cancer (IARC) (2008) WHO Classification of Tumours of Hematopoietic and Lymphoid Tissues. 4th Edition. [2] Jain, A., Nalesnik, M., et al. (2002) Posttransplant Lymphoproliferative Disorders in Liver Transplantation. A 20-Year Experience. Jorge Reyes Annals of Surgery, 236, 429-437. [3] Parker, A., Bowles, K., Bradley, J.A., et al. (2010) Diagnosis of Post-Transplant Lymphoproliferative Disorder in Solid Organ Transplant Recipients—BCSH and BTS Guidelines. British Journal of Haematology, 149, 675-692.