The Versatility of Acellular Fetal Bovine Dermal Matrix for Head and Neck Surgical Reconstruction in Children
Affiliation(s)
1 Department of Otolaryngology-Head and Neck Surgery, Tufts Medical Center, Boston, USA. 2 Division of Pediatric Otolaryngology and Facial Plastic Surgery, Floating Hospital for Children, Boston, USA.
1 Department of Otolaryngology-Head and Neck Surgery, Tufts Medical Center, Boston, USA. 2 Division of Pediatric Otolaryngology and Facial Plastic Surgery, Floating Hospital for Children, Boston, USA.
ABSTRACT
Objectives: To describe the versatility of acellular fetal bovine dermal matrix as an alternative to human cadaveric allograft for head and neck reconstructive procedures in children. Study Design: Case series with chart review. Methods: A database of pediatric operative procedures was queried for the use of acellular fetal bovine dermal matrix over a 16-month period. Indications for reconstruction were assessed and initial parental and surgeon satisfaction with the product were noted. Results: During the time period of 3/2012 and 7/2013 a total of 8 reconstructive procedures were performed on pediatric patients using acellular fetal bovine dermal matrix. Indications for use varied and included open and transnasal endoscopic repair of encephaloceles and soft tissue reconstructions including lateral pharyngeal wall repair, cleft palate repair, and facial recontouring operations. Acellular fetal bovine dermal matrix had a subjectively increased ease of use as compared to the surgeon’s prior experience with human cadaveric acellular dermis. Every parent vocalized a greater comfort level with the use of a bovine product over the alternative of human cadaveric tissue. The cost of acellular fetal bovine dermal matrix is slightly lower than the cost of human cadaveric acellular dermis. Conclusions: Acellular fetal bovine dermal matrix appears to be an acceptable alternative to human cadaveric acellular dermis for various forms of head and neck soft tissue reconstruction in children. Further prospective studies are warranted to assess for any differences in the long-term efficacy of this product as compared to other forms of allograft reconstruction.
Objectives: To describe the versatility of acellular fetal bovine dermal matrix as an alternative to human cadaveric allograft for head and neck reconstructive procedures in children. Study Design: Case series with chart review. Methods: A database of pediatric operative procedures was queried for the use of acellular fetal bovine dermal matrix over a 16-month period. Indications for reconstruction were assessed and initial parental and surgeon satisfaction with the product were noted. Results: During the time period of 3/2012 and 7/2013 a total of 8 reconstructive procedures were performed on pediatric patients using acellular fetal bovine dermal matrix. Indications for use varied and included open and transnasal endoscopic repair of encephaloceles and soft tissue reconstructions including lateral pharyngeal wall repair, cleft palate repair, and facial recontouring operations. Acellular fetal bovine dermal matrix had a subjectively increased ease of use as compared to the surgeon’s prior experience with human cadaveric acellular dermis. Every parent vocalized a greater comfort level with the use of a bovine product over the alternative of human cadaveric tissue. The cost of acellular fetal bovine dermal matrix is slightly lower than the cost of human cadaveric acellular dermis. Conclusions: Acellular fetal bovine dermal matrix appears to be an acceptable alternative to human cadaveric acellular dermis for various forms of head and neck soft tissue reconstruction in children. Further prospective studies are warranted to assess for any differences in the long-term efficacy of this product as compared to other forms of allograft reconstruction.
KEYWORDS
Acellular Fetal Bovine Dermal Matrix (SurgiMend), Human Cadaveric Acellular Dermal Allograft (AlloDerm), Skull Base, Cerebrospinal Fluid Leak Repair, Pediatric, Atrophic Scar, Parotidectomy Defect, Parry Romberg, Cleft Palate
Acellular Fetal Bovine Dermal Matrix (SurgiMend), Human Cadaveric Acellular Dermal Allograft (AlloDerm), Skull Base, Cerebrospinal Fluid Leak Repair, Pediatric, Atrophic Scar, Parotidectomy Defect, Parry Romberg, Cleft Palate
Cite this paper
Tracy, J. , Kim, W. and Scott, A. (2014) The Versatility of Acellular Fetal Bovine Dermal Matrix for Head and Neck Surgical Reconstruction in Children. International Journal of Clinical Medicine, 5, 1119-1124. doi: 10.4236/ijcm.2014.518143.
Tracy, J. , Kim, W. and Scott, A. (2014) The Versatility of Acellular Fetal Bovine Dermal Matrix for Head and Neck Surgical Reconstruction in Children. International Journal of Clinical Medicine, 5, 1119-1124. doi: 10.4236/ijcm.2014.518143.
References
[1] Banks, C.A., Palmer, J.N., Chiu, A.G., O’Malley Jr., B.W., Woodworth, B.A. and Kennedy, D.W. (2009) Endoscopic Closure of CSF Rhinorrhea: 193 Cases over 21 Years. Otolaryngology-Head and Neck Surgery, 140, 826-833.
http://dx.doi.org/10.1016/j.otohns.2008.12.060 [2] Shridharani, S.M. and Tufaro, A.P. (2012) Systematic Review of Acellular Dermal Matrices in Head and Neck Reconstruction. Plastic and Reconstructive Surgery, 130, 35S-43S.
http://dx.doi.org/10.1097/PRS.0b013e31825eff7a [3] Kridel, R.W., Foda, H. and Lunde, K.C. (1998) Septal Perforation Repair with Acellular Human Dermal Allograft. Archives of Otolaryngology-Head and Neck Surgery, 124, 73-78.
http://dx.doi.org/10.1001/archotol.124.1.73 [4] Sachsman, S.M. and Rice, D.H. (2007) Use of AlloDerm Implant to Improve Cosmesis after Parotidectomy. Ear, Nose Throat Journal, 86, 512-513. [5] Girod, D.A., Sykes, K., Jorgensen, J., Tawfik, O. and Tsue, T. (2009) Acellular Dermis Compared to Skin Grafts in Oral Cavity Reconstruction. Laryngoscope, 119, 2141-2149.
http://dx.doi.org/10.1002/lary.20548 [6] Munson, P.D. and Moore, E.J. (2010) Pediatric Endoscopic Skull Base Surgery. Current Opinion in Otolaryngology Head and Neck Surgery, 18, 571-576.
http://dx.doi.org/10.1097/MOO.0b013e3283401fdc [7] Achauer, B.M., VanderKam, V.M., Celikoz, B. and Jacobson, D.G. (1998) Augmentation of Facial Soft-Tissue Defects with AlloDerm Dermal Graft. Annals of Plastic Surgery, 41, 503-507.
http://dx.doi.org/10.1097/00000637-199811000-00009 [8] Aldekhayel, S.A., Sinno, H. and Gilardino, M.S. (2012) Acellular Dermal Matrix in Cleft Palate Repair: An Evidence-Based Review. Plastic and Reconstructive Surgery, 130, 177-182.
http://dx.doi.org/10.1097/PRS.0b013e318254b2dc [9] Shah, R.N., Surowitz, J.B., Patel, M.R., et al. (2009) Endoscopic Pedicled Nasoseptal Flap Reconstruction for Pediatric Skull Base Defects. Laryngoscope, 119, 1067-1075.
http://dx.doi.org/10.1002/lary.20216 [10] Lorenz, R.R., Dean, R.L., Hurley, D.B., Chuang, J. and Citardi, M.J. (2003) Endoscopic Reconstruction of Anterior and Middle Cranial Fossa Defects Using Acellular Dermal Allograft. Laryngoscope, 113, 496-501.
http://dx.doi.org/10.1097/00005537-200303000-00019 [11] Clark, D.W., Citardi, M.J. and Fakhri, S. (2010) Endoscopic Management of Skull Base Defects Associated with Persistent Pneumocephalus Following Previous Open Repair: A Preliminary Report. Otolaryngology-Head and Neck Surgery, 142, 820-826.
http://dx.doi.org/10.1016/j.otohns.2009.12.041 [12] Hadad, G., Bassagasteguy, L., Carrau, R.L., et al. (2006) A Novel Reconstructive Technique after Endoscopic Expanded Endonasal Approaches: Vascular Pedicle Nasoseptal Flap. Laryngoscope, 116, 1882-1886.
http://dx.doi.org/10.1097/01.mlg.0000234933.37779.e4 [13] Ismail, A.S., Cos-tantino, P.D. and Sen, C. (2007) Transnasal Transsphenoidal Endoscopic Repair of CSF Leakage Using Multilayer Acellular Dermis. Skull Base, 17, 125-131.
http://dx.doi.org/10.1055/s-2007-970556 [14] Cheng, A. and Saint-Cyr, M. (2012) Comparison of Different ADM Materials in Breast Surgery. Clinics in Plastic Surgery, 39, 167-175.
http://dx.doi.org/10.1016/j.cps.2012.02.004 [15] Butterfield, J.L. (2013) 440 Consecutive Immediate, Implant-Based, Single-Surgeon Breast Reconstructions in 281 Patients: A Comparison of Early Outcomes and Costs between SurgiMend Fetal Bovine and AlloDerm Human Cadaveric Acellular Dermal Matrices. Plastic and Reconstructive Surgery, 131, 940-951.
http://dx.doi.org/10.1097/PRS.0b013e3182865ab3 [16] Tracy, J.C., Sillman, J., Vecchiotti, M.A. and Scott, A.R. (2014) The Use of Acellular Fetal Bovine Derived Autograft for Pediatric Skull Base Reconstruction. Presented as a Poster Presentation at the 24th Annual North American Skull Base Society Meeting, San Diego, 14-16 February 2014.
[1] Banks, C.A., Palmer, J.N., Chiu, A.G., O’Malley Jr., B.W., Woodworth, B.A. and Kennedy, D.W. (2009) Endoscopic Closure of CSF Rhinorrhea: 193 Cases over 21 Years. Otolaryngology-Head and Neck Surgery, 140, 826-833.
http://dx.doi.org/10.1016/j.otohns.2008.12.060 [2] Shridharani, S.M. and Tufaro, A.P. (2012) Systematic Review of Acellular Dermal Matrices in Head and Neck Reconstruction. Plastic and Reconstructive Surgery, 130, 35S-43S.
http://dx.doi.org/10.1097/PRS.0b013e31825eff7a [3] Kridel, R.W., Foda, H. and Lunde, K.C. (1998) Septal Perforation Repair with Acellular Human Dermal Allograft. Archives of Otolaryngology-Head and Neck Surgery, 124, 73-78.
http://dx.doi.org/10.1001/archotol.124.1.73 [4] Sachsman, S.M. and Rice, D.H. (2007) Use of AlloDerm Implant to Improve Cosmesis after Parotidectomy. Ear, Nose Throat Journal, 86, 512-513. [5] Girod, D.A., Sykes, K., Jorgensen, J., Tawfik, O. and Tsue, T. (2009) Acellular Dermis Compared to Skin Grafts in Oral Cavity Reconstruction. Laryngoscope, 119, 2141-2149.
http://dx.doi.org/10.1002/lary.20548 [6] Munson, P.D. and Moore, E.J. (2010) Pediatric Endoscopic Skull Base Surgery. Current Opinion in Otolaryngology Head and Neck Surgery, 18, 571-576.
http://dx.doi.org/10.1097/MOO.0b013e3283401fdc [7] Achauer, B.M., VanderKam, V.M., Celikoz, B. and Jacobson, D.G. (1998) Augmentation of Facial Soft-Tissue Defects with AlloDerm Dermal Graft. Annals of Plastic Surgery, 41, 503-507.
http://dx.doi.org/10.1097/00000637-199811000-00009 [8] Aldekhayel, S.A., Sinno, H. and Gilardino, M.S. (2012) Acellular Dermal Matrix in Cleft Palate Repair: An Evidence-Based Review. Plastic and Reconstructive Surgery, 130, 177-182.
http://dx.doi.org/10.1097/PRS.0b013e318254b2dc [9] Shah, R.N., Surowitz, J.B., Patel, M.R., et al. (2009) Endoscopic Pedicled Nasoseptal Flap Reconstruction for Pediatric Skull Base Defects. Laryngoscope, 119, 1067-1075.
http://dx.doi.org/10.1002/lary.20216 [10] Lorenz, R.R., Dean, R.L., Hurley, D.B., Chuang, J. and Citardi, M.J. (2003) Endoscopic Reconstruction of Anterior and Middle Cranial Fossa Defects Using Acellular Dermal Allograft. Laryngoscope, 113, 496-501.
http://dx.doi.org/10.1097/00005537-200303000-00019 [11] Clark, D.W., Citardi, M.J. and Fakhri, S. (2010) Endoscopic Management of Skull Base Defects Associated with Persistent Pneumocephalus Following Previous Open Repair: A Preliminary Report. Otolaryngology-Head and Neck Surgery, 142, 820-826.
http://dx.doi.org/10.1016/j.otohns.2009.12.041 [12] Hadad, G., Bassagasteguy, L., Carrau, R.L., et al. (2006) A Novel Reconstructive Technique after Endoscopic Expanded Endonasal Approaches: Vascular Pedicle Nasoseptal Flap. Laryngoscope, 116, 1882-1886.
http://dx.doi.org/10.1097/01.mlg.0000234933.37779.e4 [13] Ismail, A.S., Cos-tantino, P.D. and Sen, C. (2007) Transnasal Transsphenoidal Endoscopic Repair of CSF Leakage Using Multilayer Acellular Dermis. Skull Base, 17, 125-131.
http://dx.doi.org/10.1055/s-2007-970556 [14] Cheng, A. and Saint-Cyr, M. (2012) Comparison of Different ADM Materials in Breast Surgery. Clinics in Plastic Surgery, 39, 167-175.
http://dx.doi.org/10.1016/j.cps.2012.02.004 [15] Butterfield, J.L. (2013) 440 Consecutive Immediate, Implant-Based, Single-Surgeon Breast Reconstructions in 281 Patients: A Comparison of Early Outcomes and Costs between SurgiMend Fetal Bovine and AlloDerm Human Cadaveric Acellular Dermal Matrices. Plastic and Reconstructive Surgery, 131, 940-951.
http://dx.doi.org/10.1097/PRS.0b013e3182865ab3 [16] Tracy, J.C., Sillman, J., Vecchiotti, M.A. and Scott, A.R. (2014) The Use of Acellular Fetal Bovine Derived Autograft for Pediatric Skull Base Reconstruction. Presented as a Poster Presentation at the 24th Annual North American Skull Base Society Meeting, San Diego, 14-16 February 2014.